Gene Information

Name : clpC (SAI7S6_1004010)
Accession : YP_007584960.1
Strain : Staphylococcus aureus ST228 (isolate=18412)
Genome accession: NC_020537
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 538752 - 541208 bp
Length : 2457 bp
Strand : +
Note : -

DNA sequence :
ATGTTATTTGGTAGATTAACTGAACGTGCACAGCGCGTATTAGCACATGCACAAGAAGAAGCAATTCGTTTAAATCATTC
AAATATAGGAACAGAACACCTATTATTGGGGTTAATGAAAGAACCTGAAGGAATTGCTGCAAAAGTATTAGAAAGTTTTA
ATATCACTGAAGATAAAGTAATTGAAGAAGTTGAAAAATTAATCGGACATGGTCAAGATCATGTTGGTACATTGCATTAT
ACACCTAGAGCTAAAAAAGTCATTGAATTATCGATGGATGAAGCTAGAAAATTACATCACAATTTTGTTGGAACGGAACA
TATTTTATTAGGCTTGATTCGTGAAAATGAAGGTGTTGCAGCAAGAGTTTTTGCAAATCTAGATTTAAATATTACTAAAG
CACGTGCACAAGTTGTGAAAGCTTTAGGAAACCCTGAAATGAGTAATAAAAATGCACAAGCTAGTAAGTCAAATAATACT
CCAACTTTAGATAGTTTAGCTCGTGACTTAACAGTCATTGCCAAAGACGGTACATTAGATCCTGTTATAGGACGTGATAA
AGAAATTACACGTGTAATTGAAGTATTAAGTAGACGTACGAAAAACAATCCTGTACTTATTGGAGAGCCAGGTGTTGGTA
AAACTGCTATTGCTGAAGGTTTAGCGCAAGCCATAGTGAATAATGAGGTACCAGAGACATTAAAAGATAAGCGTGTTATG
TCTTTAGATATGGGAACAGTAGTTGCAGGTACTAAATATCGTGGTGAATTTGAAGAGCGTCTGAAAAAGGTTATGGAAGA
AATCCAACAAGCAGGTAATGTCATCCTATTTATTGATGAGTTGCATACTTTAGTTGGTGCTGGTGGTGCTGAAGGTGCTA
TCGATGCTTCGAATATTTTGAAACCGGCATTAGCACGTGGTGAATTACAATGTATTGGTGCTACTACATTAGATGAATAT
CGCAAAAATATTGAAAAAGACGCGGCTTTAGAACGTCGTTTCCAACCTGTACAAGTTGATGAACCTTCAGTAGTAGATAC
AGTTGCTATTTTAAAAGGATTAAGAGATCGTTACGAAGCACACCATCGTATTAATATTTCAGACGAAGCTATTGAAGCAG
CTGTTAAATTAAGTAACAGATACGTTTCAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCAAGTTCT
AAAGTAAGACTTAAGAGTCATACGACACCTAATAATTTAAAAGAAATTGAACAAGAAATTGAAAAAGTTAAAAATGAAAA
AGATGCCGCAGTACATGCTCAAGAGTTTGAAAATGCTGCTAACCTGCGTGATAAACAAACAAAACTTGAAAAGCAATATG
AAGAAGCTAAAAATGAATGGAAGAATGCACAAAATGGCATGTCAACTTCATTGTCAGAAGAAGATATTGCTGAAGTTATT
GCAGGATGGACAGGTATCCCATTAACTAAAATCAATGAAACAGAATCTGAAAAACTTCTTAGTCTAGAAGATACATTACA
TGAGAGAGTTATTGGGCAAAAAGATGCTGTTAATTCAATCAGTAAAGCGGTTAGACGTGCCCGTGCAGGGTTAAAAGATC
CTAAACGACCAATTGGTAGCTTTATCTTCCTTGGACCAACTGGTGTTGGTAAAACTGAATTAGCTAGAGCTTTAGCTGAA
TCAATGTTTGGCGATGATGATGCGATGATCCGTGTAGACATGAGTGAATTTATGGAAAAACACGCAGTGAGCCGATTAGT
TGGTGCTCCTCCAGGATATGTTGGTCATGATGATGGTGGACAATTAACTGAAAAAGTTAGACGTAAACCATATTCTGTAA
TTTTATTTGATGAAATTGAAAAAGCTCATCCAGATGTATTTAATATTCTATTACAAGTTTTAGATGATGGACATTTGACA
GATACAAAAGGACGTACAGTTGATTTCAGAAATACAATTATCATAATGACATCAAACGTTGGGGCACAAGAATTACAAGA
TCAACGATTTGCTGGATTCGGTGGTTCAAGTGATGGACAAGATTATGAAACAATTCGAAAAACGATGTTAAAAGAATTAA
AAAATTCATTCCGTCCAGAATTTTTAAACCGTGTAGATGATATCATTGTATTCCATAAACTAACAAAAGAAGAATTAAAA
GAAATTGTAACAATGATGGTTAATAAATTAACAAATCGATTATCTGAACAAAACATAAATATTATTGTTACTGATAAAGC
GAAAGACAAAATCGCAGAAGAAGGATATGATCCAGAATATGGTGCAAGACCATTAATTAGAGCGATACAAAAAACTATCG
AAGATAATTTAAGTGAATTAATATTAGATGGTAATCAAATTGAAGGTAAGAAAGTTACAGTAGATCATGATGGTAAAGAG
TTTAAATATGACATTGCTGAACAAACTTCAGAAACTAAAACACCATCGCAAGCATAA

Protein sequence :
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHY
TPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNT
PTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVM
SLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASS
KVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNAQNGMSTSLSEEDIAEVI
AGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLT
DTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELK
EIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKE
FKYDIAEQTSETKTPSQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_007584960.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 0.0 71
clpC YP_007584960.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 2e-165 52