Gene Information

Name : LPE509_02183 (LPE509_02183)
Accession : YP_007568726.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_020521
Putative virulence/resistance : Resistance
Product : Lead, cadmium, zinc and mercury transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2325574 - 2327760 bp
Length : 2187 bp
Strand : -
Note : FIG00658111

DNA sequence :
ATGCCTCATTCATTGCAAGGGTTATATTTTACGGACAATGCGGAAAACCAAATGACAGTACCTTTAAATGAAATCAAATT
TTTTGTTGCAGGACTTGATTGTCCAGCAGAAGAGCAGCTTATCAGAAAGCAGTTTCAGGATATTCCTGAAGTGGAGCAGT
TGGATTTTAATTTTATTGCTGAAGAAGTTACCATTCATCACCGGTTGGCTTCAAGTGAAGAATTGCAAAAACGCATTGAG
GTGTTGGGAATGAGTGTTCGAACGCTGGAAAGCACTTTACCTATACCACAAAGAAAACAATTATCGTTGGATTTTTCCTG
GAAAATTATTGGACTAGCAGGTTTTCTTGCCCTATTTTCTGAGCTGGCAGCTTATTTTTTGGCTACGGAACAATCCATTT
GGACTATTCTTCCAGCTTTGTTGGCTATTGGTCTTAGTGGGCCTTCTACCTTTAAAAAAGGGTGGCTTGCCTTAGGGACT
AAAACAATGAATATCAATAGCTTGATGTTCATTGCGATAGCAGGGGCTGTTCTTATTGGAGAGTGGCCTGAAGCGGCAAT
GGTGACTGTTTTATTTGCATTGGCTGAACGTATCGAGCGCTACTCCTTAGATAAAGCACGTCTTGCGATTCGAAGCTTAA
TGCAAATTGCCCCTGAGGTAGCTTCGGTGAAACAGGACGATGGTCAATGGCAAACCTTGGCCATTGAAAAAGTGGTGCCT
GGTGCTGTTTTTAGAGTAAAACCTGGAGAGCGTATTCCTCTGGATGGTGTTGTTATTTCAGGTCAGAGCACGGTCAATCA
AGCGCCGATTACTGGTGAATCAATGCCAATAACAAAAAAAGTAGGCGATTTGGTTTTTGCAGGAACATTAAATGAGCACG
GCGCGTTTGAAGTGCAGGTCAGTAAAGCGTCAGGCGATACATTGCTTGCTAAAATTGGTAAAGCGATAGAGCAAGCGCAA
GCGGATCGAGCCCCAACGCAACGATTTGTTGATCAATTTTCTAAATATTACACTCCAATTATGGTATTGATGGCTTTTTT
TGTTGCATTAATTCCACCTTTAGCATTTGGTTATCCTTTTTATGATTCTCTTTATAAGTCACTGACTTTATTAGTTATTG
CTTGCCCTTGCGCTTTAGTGATTTCAACACCCGTGACTGTTGTAAGTGGCCTTGCAGCGGCAGCAAAACAAGGGCTTCTT
ATTAAAGGAGGAAGCTACTTAGAGGTTGGTCATCGACTGAGGTTAATTGCTTTAGATAAGACAGGTACTTTAACGGAAGG
AAAGCCAGTTGTAACTGACTTCATAGCTTGGGATGAAAATCGAACTAAGGAGAGTTTGTTATTGTTAGCTGCAAGCCTTG
ATAGTCACTCGGAGCATCCAGTCGCTAATGCCTTAGTACAGTACTGGCAACAGGAACAACCCCAAAACGCTTTACTTGAA
ATTGAACAATTTTCAGCACTTCCTGGACGAGGAGTAAAAGGATTGGTGGGTCAAGAACTCTATTTTGTAGGCAATCATCA
GTTAGCTGAAGACAATCAGGTATGCAATCATTTTGTCGAACAAGAGCTGAAGCGCTTGGAGGAAGAAGGTAAAACGACCG
TAATATTAAGTAATGCTACGACGGTTTTGGCTATTTTTGCAGTAGCTGATACGTTACGTGTTACAAGCCAACAGGCGATT
GCACAACTCCATGAACGGGGCATAAAAACCGCGATGTTAACGGGAGACAATGCGGTAACGGCTCAGGCTATTGCTAAAAA
AGTAGGTATTGATGAAGTAAATGCAAATATATTGCCTGCGGAAAAACTGCAAGCGATTAATCGTCTTTTAGAACACTATC
ATAGCGTTGGGATGGTAGGAGATGGAATTAATGATGCCCCTGCATTGGCAAAAGCTACCGTGAGTTTTGCGATGGGGAAA
GGAACAGATACTGCCTTAGAAACTGCTGACGTTGCCCTAATGAATGACAATCTAGCAAGACTTCCCTTTTATGTTGATTT
AAGTCGTAAGACGGCACGTACTCTTTATCAAAACATCAGTTTATCTATTGCGATTAAAGGCATTTTCTTTATTTTAGCTC
TTGTAGGGTATGCAACGTTATGGATGGCAGTTTTTGCAGACATGGGAGCGAGTTTAATCGTAGTGGCTAATGGTTTGCGA
TTGTTGTATATGTCTCCAGATGATTAA

Protein sequence :
MPHSLQGLYFTDNAENQMTVPLNEIKFFVAGLDCPAEEQLIRKQFQDIPEVEQLDFNFIAEEVTIHHRLASSEELQKRIE
VLGMSVRTLESTLPIPQRKQLSLDFSWKIIGLAGFLALFSELAAYFLATEQSIWTILPALLAIGLSGPSTFKKGWLALGT
KTMNINSLMFIAIAGAVLIGEWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIAPEVASVKQDDGQWQTLAIEKVVP
GAVFRVKPGERIPLDGVVISGQSTVNQAPITGESMPITKKVGDLVFAGTLNEHGAFEVQVSKASGDTLLAKIGKAIEQAQ
ADRAPTQRFVDQFSKYYTPIMVLMAFFVALIPPLAFGYPFYDSLYKSLTLLVIACPCALVISTPVTVVSGLAAAAKQGLL
IKGGSYLEVGHRLRLIALDKTGTLTEGKPVVTDFIAWDENRTKESLLLLAASLDSHSEHPVANALVQYWQQEQPQNALLE
IEQFSALPGRGVKGLVGQELYFVGNHQLAEDNQVCNHFVEQELKRLEEEGKTTVILSNATTVLAIFAVADTLRVTSQQAI
AQLHERGIKTAMLTGDNAVTAQAIAKKVGIDEVNANILPAEKLQAINRLLEHYHSVGMVGDGINDAPALAKATVSFAMGK
GTDTALETADVALMNDNLARLPFYVDLSRKTARTLYQNISLSIAIKGIFFILALVGYATLWMAVFADMGASLIVVANGLR
LLYMSPDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 4e-158 52
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-122 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-121 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-121 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LPE509_02183 YP_007568726.1 Lead, cadmium, zinc and mercury transporting ATPase BAC0298 Protein 4e-156 52