Gene Information

Name : clpC (Bbr_1356)
Accession : YP_007555154.1
Strain : Bifidobacterium breve UCC2003
Genome accession: NC_020517
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1689996 - 1692605 bp
Length : 2610 bp
Strand : -
Note : -

DNA sequence :
ATGTTCGAACGGTTTACCGACCGTGCACGGCGCGTGATCGTGTTGGCGCAGGAAGAGGCGAGGACTCTCCAGCACAACTA
CATCGGCACCGAACACCTGCTGCTCGGCCTGATCCGAGAGGGTGAGGGCGTGGCCGCCAAGGCACTCGCCTCGAAGGGCG
TGGAGTTGGACGCCACCCGCAAGCAGGTCGAAGAGATGATCGGCAAGGGCAACGCGGCCCCGAACGGGCACATCCCCTTT
ACCCCGCATGCCAAGCAGGTGCTGGAGTTCTCGTTGCGTGAGGCTTTGCAGTTGGGCCACAGCTACATCGGCACTGAGCA
TATTCTGCTCGGCTTGATTCGCGAGGGTGAAGGCGTGGGCACTCAGGTGCTCATTAAGATGGACGTTGATTTGGGCGAGC
TGCGCAGCGCAACCATCGATATGATTCGCGGCAACTCCGGCACCTCCACTGACGGCAAGGGCGATTTGGCCAACGCCGGT
GGCGTGGCGGACAAGCAGAACAAGTCCGGTTCCGCCATTCTCGACCAGTTCGGCCGCAACCTGACCGCCGAAGCCGCCGA
AGGCAAGTTGGATCCGGTCATCGGCCGTACTAATGAGATCGAGCGCGTTATGGTCGTGCTCTCCCGCCGCACCAAGAACA
ACCCGGTGCTGATCGGCGAGCCAGGTGTGGGCAAGACCGCTGTGGTCGAAGGACTGGCCCAGAAGATTCAGGCCGGCGAT
GTGCCGGAGACCTTGAAAGGCAAGCAGGTCTACTCGCTGGATCTTGGTTCCATGGTGGCCGGTTCCCGTTACCGTGGTGA
TTTCGAGGAGCGTCTGAAGAAGGTCCTGAAGGAAATCAAGACCCGCGGCGACATCGTGCTGTTCATCGACGAGATCCACA
CCATCGTGGGGGCTGGCTCTGCCGACGGCGCACTGGGTGCCTCCGATATGTTGAAGCCGATGCTGGCCCGTGGCGAGCTG
CAGACCATCGGCGCCACCACCACCGACGAGTACCGCAAGTACATCGAGAAGGACGCGGCGCTGGAACGCCGATTCCAGCC
CATCCAGGTGCATGAGCCGACCATCGCCGAGACCATTGAAATCTTGAAGGGCCTGCGTTCTCGCTACGAGAACCACCATC
ACGTGACCATCACCGATGGTGCGTTGCAGTCTGCCGCAGAGCTTTCCAGCCGCTATATTCAGGATCGCAACCTGCCGGAT
AAGGCCATCGATTTGATCGACGAGGCCGGTGCCCGCCTGCGCATCAAGCGTCTGACCGCACCGCCCGAGCTCAAGGAGCT
TGACGACAAGATCGCCAAGATCGCCGCCGACAAGGACGAGGCCATCAAGGGCCAGGACTTCGAGAAGGCCGCCGAACTGC
GCGACAACCAAGAGAAGTTGGAAGCCGAGCGCAAGGCGAAGGAAGATTCCTGGCGCGAAGGCGAGTCCGACGTCAAGATG
GTCGTGGATGAGGACGTGATCGCCGAGGTCATCAGCGCCACCACCGGTATTCCGGTGTTCAAGCTGACCCAGGCTGAGTC
CAAGAAGCTGCTCAACATGGAAGCCGAGCTGCACAAGCGCATTATCGGCCAGGATGAGGCGGTGTCCGCCCTGTCCCGCT
CCATCCGCCGTACCCGCGTGGGCCTGAAGGACCCGAAGCGCCCGTCCGGTTCGTTCATCTTTGCCGGCCCCACCGGCGTG
GGCAAGACCGAGCTGGCCAAGACGCTGGCCGAGTTCCTGTTCGACGATGAGGATGCGCTGATTCGCGTCGATATGTCCGA
GTTCTCCGAGAAGTATGCGGCATCGCGTCTCTTTGGTGCGCCTCCGGGATACGTCGGTTATGAGGAGGGCGGCGAGCTCA
CCGAGAAGGTGCGCCGCAAGCCGTTCTCCGTGGTGCTGTTCGACGAGATCGAGAAGGCGCATCCGGATATCTTCAACACG
CTGCTGCAGGTGCTGGATGACGGCCATCTGACCGACGGTCAGGGCCGCAAAGTGGACTTCAAGAACACCATCATCATCCT
GACCACCAACTTGGGCACCCGCGACATTGCCAAAGCCGCCAACACCGGCTTCAACCTCGGCGCGAACACCGAGTCGAGCT
ATCAGCGCATGAAGGATCAGGTGAGTTCGGAGCTGAAGCAGCAGTTCCGTCCCGAGTTCCTCAACCGTTTGGACGACATC
ATCGTTTTCAAGCAGCTGACTGAGCCGGAGGTGCGTCAGATCGTCGATCTCGATGTCAAGCAGCTCAACGATCGTCTGTT
CGACCGCCACATGTCGCTCGAACTTACCGACGCCGCCAAGGATCTGCTCGCGCAGAAGGGCTTTGACCCGCTGCTCGGCG
CTCGTCCGCTGCGCCGTGTGATTCAGCGCGACATCGAGGACGCCATCTCCGAGAAGATCCTGATGGGCGACCTCGAAGAC
GGCCAGCGCGTGATCGTGGACGCGGAAGGCGAAGGCATTCTCGGCGAATTCACCTTCAAGGGTGAACAGTTCGAGGAGCC
GGCCGTCGCCGATAAGCCGTCCGAAGACGGTGTTGACGGTGCTGGCTCTGACGGTGAGGCACCGGCAGAAGCCGCTCCGG
CCGCTGAACAGACCGAAGCCTCCGACTCCAACGACACTCCACAGGAGTAA

Protein sequence :
MFERFTDRARRVIVLAQEEARTLQHNYIGTEHLLLGLIREGEGVAAKALASKGVELDATRKQVEEMIGKGNAAPNGHIPF
TPHAKQVLEFSLREALQLGHSYIGTEHILLGLIREGEGVGTQVLIKMDVDLGELRSATIDMIRGNSGTSTDGKGDLANAG
GVADKQNKSGSAILDQFGRNLTAEAAEGKLDPVIGRTNEIERVMVVLSRRTKNNPVLIGEPGVGKTAVVEGLAQKIQAGD
VPETLKGKQVYSLDLGSMVAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGASDMLKPMLARGEL
QTIGATTTDEYRKYIEKDAALERRFQPIQVHEPTIAETIEILKGLRSRYENHHHVTITDGALQSAAELSSRYIQDRNLPD
KAIDLIDEAGARLRIKRLTAPPELKELDDKIAKIAADKDEAIKGQDFEKAAELRDNQEKLEAERKAKEDSWREGESDVKM
VVDEDVIAEVISATTGIPVFKLTQAESKKLLNMEAELHKRIIGQDEAVSALSRSIRRTRVGLKDPKRPSGSFIFAGPTGV
GKTELAKTLAEFLFDDEDALIRVDMSEFSEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFDEIEKAHPDIFNT
LLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDIAKAANTGFNLGANTESSYQRMKDQVSSELKQQFRPEFLNRLDDI
IVFKQLTEPEVRQIVDLDVKQLNDRLFDRHMSLELTDAAKDLLAQKGFDPLLGARPLRRVIQRDIEDAISEKILMGDLED
GQRVIVDAEGEGILGEFTFKGEQFEEPAVADKPSEDGVDGAGSDGEAPAEAAPAAEQTEASDSNDTPQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_007555154.1 Negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 57
clpC YP_007555154.1 Negative regulator of genetic competence clpC/mecB VFG0080 Protein 2e-136 51