Gene Information

Name : clpB (HPOK310_0268)
Accession : YP_007537902.1
Strain : Helicobacter pylori OK310
Genome accession: NC_020509
Putative virulence/resistance : Virulence
Product : ATP-dependent protease binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 275599 - 278169 bp
Length : 2571 bp
Strand : +
Note : -

DNA sequence :
ATGAATTTATTTGAAAAAATGACCGACCAATTGCATGAGACTTTAGACAGCGCGCTCGCTCTAGCCTTACACCATAAAAA
CGCTGAAGTAACGCCCTTGCACATGCTTTTTGTCATGCTCAATAACTCCCAAGGCATCCTCATTCAAGCCTTACAAAAAA
TGTCTGTGGATATTCAAGCCTTAAGGCTTAGCGTTCAAAGCGAGTTGAATAAGTTGGCTAAAGTTTCACAAATCAACAAG
CAAAATATCCAGTTAAACCAAGCTCTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAATGGGCGATTCTTT
CATCGCTACAGATGTGTATCTTTTGGCGAACATGAGCCTTTTTGAAAGCGTTCTAAAACCTTATTTAGACACTAAGGAAT
TGCAAAAAACTTTAGAGGCTTTAAGAAAAGGCGCGACTATCCAAAGTAAAAACGATGATTCTAATTTTGAAAGTTTGGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCTTAGAAAATAAGCTCGATCCGGTGATTGGGAGGGATGAAGAAATCATTCG
CATGATGCAAATTTTGATAAGAAAAACAAAAAATAACCCTATTTTATTGGGTGAGCCTGGAGTGGGGAAAACGGCGGTTG
TGGAGGGTTTGGCCCAACGCATTGTGAATAAGGAAGTGCCTAAAACGCTTTTAAACAAACGAGTCGTCGCTTTAGATTTA
AGCTTATTGGTGGCTGGAGCGAAATACAGAGGCGAGTTTGAAGAGCGCTTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATTGTAGGGGCTGGAGCTAGTGAGGGAGGCATGGATGCGGCTA
ATATTTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTTTGAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCGTTACAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAGGCTTTACAGATTTT
AAGGGGGTTAAAAGAAACTTTAGAAACGCACCATAATATCACCATCAATGACTCTGCGCTCATAGCGAGCACTAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGGGCGGCCCAATTAAAAATG
CAAATGGAATCAGAGCCGGCAAAACTCTCTAGCGTTAAGCGCTCCATTCAAAGATTAGAAATGGAAAAACAAGCCCTTGA
AATGGAAAAAAAAGAGAGCAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATTTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAAAACGAAAAAGAAGTGTTTAGAGAAATTTCACGCTTGAAAATGGAAACGGAAAGCTTGAAA
AAAGAGGCTGAGAGGTTTAAGCGCAATGGGGATTACCAGCAAGCGGGTGAAATTGAATACTCTAAAATCCCTGAAAATAA
AAAGAAAGAAGAAGAATTGCAGCATAAATGGGAAGCGATGCAACAAAACGGGGCGTTATTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCATATCCCGGTCCAAAAAATGCTCCAAAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGAGTGGTGGGGCAAGAAAAAGCAATCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCCGGGCTTAGCGATAGCAATAAACCCATAGGGAGTTTTCTCTTTTTAGGGCCAACGGGTGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATAAGAATTGACATGAGCGAATACATGGAAAAA
CATGCAATAAGCCGTCTTATTGGGGCTGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAACCCTACAGCGTAGTGCTGTTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAATCTTTTGTTGCAGGTTT
TAGATGAAGGGCATTTAACCGATAGTAAGGGCGTGAGAGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGCACGCTTTTGGAAGAGAATTTGAGTGAAGCCGATAAACAAAAAGCGATTAAAGAGAGTTTGAGGCAATTCTT
CAAGCCGGAATTTTTAAACCGCTTAGATGAAATCATCTCCTTTAACGCCCTAAATAGCCATGCTGTCGCTAATATCGTGG
GGATACTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGGGGCATTAATATAACCCTAGACGAAGAGGCAAAAGAATTG
ATCGCTGAAGCGGGATTTGACAGATTTTATGGCGCTAGACCCTTAAAGCGCGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAATTAAAGAGAATGACAGCGTGGCGTTTGTGGTAGAAAATAACGAAATTGTGCCTA
AGATTAAGTGA

Protein sequence :
MNLFEKMTDQLHETLDSALALALHHKNAEVTPLHMLFVMLNNSQGILIQALQKMSVDIQALRLSVQSELNKLAKVSQINK
QNIQLNQALIQSLENAQGLMAKMGDSFIATDVYLLANMSLFESVLKPYLDTKELQKTLEALRKGATIQSKNDDSNFESLE
KFGIDLTQKALENKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVVALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASTKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFREISRLKMETESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYMEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGTLLEENLSEADKQKAIKESLRQFFKPEFLNRLDEIISFNALNSHAVANIVGILFENIQKKALERGINITLDEEAKEL
IAEAGFDRFYGARPLKRALYEMVEDKLAELILEDKIKENDSVAFVVENNEIVPKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-139 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_007537902.1 ATP-dependent protease binding subunit VFG0079 Protein 8e-156 43
clpB YP_007537902.1 ATP-dependent protease binding subunit VFG2076 Protein 8e-112 42