Gene Information

Name : metB (HPOK310_0118)
Accession : YP_007537752.1
Strain : Helicobacter pylori OK310
Genome accession: NC_020509
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase/cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 120695 - 121837 bp
Length : 1143 bp
Strand : -
Note : -

DNA sequence :
ATGCACATGCAAACAAAACTAATCCATGGGGGCATTAGTGAGGATGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCATAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAAGGGTTTGCTTTTGCCTCTGGTTTAGCTGGGATTCACACC
GTTTTTTCTCTCTTGCAATCAGGCGATCATGTGCTATTGGGCGATGATGTCTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATCAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTTGCT
AAAGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGA
CATTGTAGTGCATAGCGGCACCAAATACTTGGGCGGTCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTGCGCATGGAAGCCCACCAAAAAAATGCCCTTTGCGTGGCTGAGTTTTTGGAAAAACACCC
TAAAGTGGAGAAGGTTTATTACCCAGGATTGCCCACTCACCCTAACCACGAACTGGCCAAAAAACAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACCCTCAAAAACGACAGCGAGGCGGTTGCTTTTGTAGAAAGCCTTAAACTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGGATTCCAGCGCTTATGACCCATGCGTGTATCCCCAAAGCGCAACGAGA
AGCTGCCGGGATTAGAGACGGCTTGGTGCGTTTGTCTGTAGGGATTGAGCATGAGCAGGATTTGTTAGAAGATTTAGAGC
AAGCTTTCGCTAAAATAGGCTAA

Protein sequence :
MHMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHT
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHGLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-98 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-99 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-73 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_007537752.1 cystathionine gamma-synthase/cystathionine beta-lyase BAC0207 Protein 2e-62 44