Gene Information

Name : metB (HPOK113_0118)
Accession : YP_007536232.1
Strain : Helicobacter pylori OK113
Genome accession: NC_020508
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase/cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 122512 - 123654 bp
Length : 1143 bp
Strand : -
Note : -

DNA sequence :
ATGCGCATGCAAACAAAATTAATCCATGGGGGCATTAGTGAGGACGCAACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCATAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGACTAGCTGGGATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGCTATTAGGCGATGATGTCTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAACGACCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATCAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTTGCT
AAAGATCATAGTTTGCTCACTATTGTGGATAATACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGA
TATTGTGGTGCATAGCGGCACCAAATACTTAGGCGGTCATAGCGATGTGGTCGCCGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAAATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGTCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTGCGCATGGAGGCCCATCAAAAAAATGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTAGAAAAGGTTTATTACCCAGGCCTTCCCACTCACCCTAACCACGAACTAGCCAAAAAACAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAGGCGGTTGCTTTTGTAGAAAGCCTTAAACTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGCTTGGTGGGAATTCCTGCACTTATGACCCATGCGTGTATCCCCAAAGCGCAACGAGA
AGCTGCCGGGATTAGAGATGGTCTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCACTAAAATAGGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNDLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHSLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFTKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-97 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-98 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-73 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_007536232.1 cystathionine gamma-synthase/cystathionine beta-lyase BAC0207 Protein 2e-61 43