Gene Information

Name : ureC (BSU6051_36640)
Accession : YP_007535658.1
Strain : Bacillus subtilis 6051-HGW
Genome accession: NC_020507
Putative virulence/resistance : Virulence
Product : urease alpha subunit UreC
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 3766719 - 3768428 bp
Length : 1710 bp
Strand : -
Note : Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12401490, 16199586, 9287005; Product type e: enzyme

DNA sequence :
ATGAAAATGTCACGGGAGGAATATGCGGAACTGTTTGGCCCGACAACGGGCGATAAAATCAGATTGGGCGACACGGATTT
ATGGATCGAAGTCGAAAAGGATTTCACAGTATACGGTGAAGAAATGATCTTTGGCGGCGGAAAAACTATCCGAGACGGCA
TGGGCCAAAACGGCAGAATCACAGGGAAGGACGGCGCTTTGGATTTGGTTATCACCAACGTCGTGCTATTGGATTACACA
GGCATTGTCAAAGCGGATGTCGGTGTGAAAGACGGCCGGATTGTCGGTGTCGGAAAAAGCGGAAATCCTGATATCATGGA
TGGAGTCGATCCGCACATGGTCATCGGAGCGGGGACAGAGGTGATTTCCGGTGAAGGCAAAATTTTAACAGCCGGGGGAG
TGGACACGCACATTCATTTTATTTGTCCTCAGCAGATGGAAGTTGCGCTTTCTTCAGGTGTGACGACCCTTTTGGGAGGC
GGAACAGGACCCGCTACAGGAAGCAAAGCGACAACATGTACGTCCGGGGCGTGGTATATGGCGAGGATGCTGGAAGCGGC
CGAGGAGTTTCCGATCAATGTCGGCTTCTTAGGAAAAGGGAATGCATCCGATAAAGCGCCGCTGATCGAGCAGGTGGAAG
CAGGCGCCATCGGTCTTAAGCTCCATGAAGACTGGGGAACGACGCCAAGCGCCATTAAAACGTGTATGGAAGTCGTGGAC
GAGGCTGATATTCAAGTTGCCATCCATACCGATACGATTAACGAAGCGGGCTTTTTGGAAAACACGCTCGACGCGATCGG
GGACCGGGTTATTCATACTTATCACATTGAAGGGGCAGGCGGCGGTCACGCTCCGGATATTATGAAGCTCGCCTCTTACG
CGAACATTCTGCCGTCATCTACAACGCCAACCATTCCTTATACCGTTAATACGATGGATGAGCATCTTGACATGATGATG
GTCTGCCACCATTTAGATGCGAAAGTGCCTGAAGATGTGGCATTCAGCCATTCCAGAATCAGGGCGGCGACGATTGCCGC
GGAGGATATTCTCCATGATATAGGTGCGATCAGCATGACATCATCGGATTCCCAAGCGATGGGGCGGGTCGGTGAAGTGA
TCATCCGAACATGGCAGGTAGCCGATAAAATGAAAAAACAGCGCGGCGCTCTTGCCGGTGAAAACGGGAATGACAATGTG
CGCGCAAAACGGTACATTGCCAAATACACGATTAATCCGGCAATTACGCACGGGCTCAGCCATGAGGTCGGCTCGGTGGA
AAAAGGGAAGCTTGCTGATCTCGTTCTGTGGGACCCGGTATTTTTCGGCGTGAAACCGGAACTGGTCTTAAAGGGCGGCA
TGATTGCACGTGCGCAAATGGGAGATCCGAACGCGTCCATCCCGACTCCTGAACCGGTTTTCATGCGCCAAATGTATGCG
TCTTACGGAAAAGCCAACCGCTCAACCTCGATTACATTTATGTCTCAGGCAAGCATAGAGCGTGGTGTGGCGGAAAGCTT
AGGGCTGGAAAAAAGGATTTCTCCAGTCAAAAATATCAGAAAGCTGAGCAAGCTGGATATGAAGCTGAATTCGGCTTTGC
CGAAGATTGAGATTGATCCAAAAACCTATCAGGTCTTTGCTGACGGGGAGGAATTGTCTTGCCAGCCTGTCGATTATGTC
CCACTTGGACAAAGATATTTCTTATTTTGA

Protein sequence :
MKMSREEYAELFGPTTGDKIRLGDTDLWIEVEKDFTVYGEEMIFGGGKTIRDGMGQNGRITGKDGALDLVITNVVLLDYT
GIVKADVGVKDGRIVGVGKSGNPDIMDGVDPHMVIGAGTEVISGEGKILTAGGVDTHIHFICPQQMEVALSSGVTTLLGG
GTGPATGSKATTCTSGAWYMARMLEAAEEFPINVGFLGKGNASDKAPLIEQVEAGAIGLKLHEDWGTTPSAIKTCMEVVD
EADIQVAIHTDTINEAGFLENTLDAIGDRVIHTYHIEGAGGGHAPDIMKLASYANILPSSTTPTIPYTVNTMDEHLDMMM
VCHHLDAKVPEDVAFSHSRIRAATIAAEDILHDIGAISMTSSDSQAMGRVGEVIIRTWQVADKMKKQRGALAGENGNDNV
RAKRYIAKYTINPAITHGLSHEVGSVEKGKLADLVLWDPVFFGVKPELVLKGGMIARAQMGDPNASIPTPEPVFMRQMYA
SYGKANRSTSITFMSQASIERGVAESLGLEKRISPVKNIRKLSKLDMKLNSALPKIEIDPKTYQVFADGEELSCQPVDYV
PLGQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-172 64
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-172 64
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-167 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-167 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-167 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-167 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_007535658.1 urease alpha subunit UreC VFG0270 Protein 2e-157 62