Gene Information

Name : gbsA (BSU6051_31060)
Accession : YP_007535093.1
Strain : Bacillus subtilis 6051-HGW
Genome accession: NC_020507
Putative virulence/resistance : Virulence
Product : glycine betaine aldehyde dehydrogenase, NAD+-dependent GbsA
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.8
Position : 3185074 - 3186546 bp
Length : 1473 bp
Strand : -
Note : Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8752328, 9297465; Product type e: enzyme

DNA sequence :
ATGAGTCAAACATTATTCATTGACGGAGAATGGATCAGTGCCGAAAAAGAACAGATCCGCAGTATTATCAACCCATTTAA
TCAAGAAGAAATTGCAACTGTAAGCGAGGGAGGGCGAGAGGACGCCATCAAAGCAATCGCAGCCGCACGTAGAGCATTTG
ACAAAGGAGAATGGTCATCGCTATCCGGGCTTGAACGCGGAAAAATTGTTCTGAAAATTGCGGAATTAATCAGACGCGAT
CTTGAGGAGCTGGCTGAGCTTGAATCTCTTGATACAGGAAAAACACTCGAAGAAAGCAAGGCCGATATGGACGATATCGC
CAATGTTTTTCAATATTACGCCGGCTTGGCAGACAAAGATGGCGGAGAGATCATTTCATCTCCGATTCCTGATTCAGAAA
GCAAAATTATTAGGGAGCCAATCGGGGTTTGCGGCCAGATCACTCCATGGAATTATCCGCTCCTTCAAGCGAGCTGGAAA
ATCGCCCCTGCACTGGCCGCAGGAAACACAATCGTCATGAAGCCGAGTGAGATTACGCCGCTGACGACAATCAAAGTCTT
TAAGCTGATGGAAGAAGCCGGTGTTCCAAAAGGTGTCGCAAATCTTGTTCTTGGACCGGGAGCCACAGTGGGCGACGAGC
TTGCCGTAAACAAAGACGTCGATTTGATTTCATTTACGGGCGGAATTGAAACAGGCAAAAAAATCATGCGGGCGGCAAGC
GGAAACGTCAAAAAAATCGCCCTTGAACTTGGCGGGAAAAACCCAAATATTGTTTTCAAGGACGCGGATTTAGAAGTTGC
GGTTGATCAGGCCTTAAACGCTGTATTTTTCCACGCCGGCCAAGTATGCTCTGCAGGTTCCCGCTTGCTTGTTGAGGATG
CCATTCATGATCAATTTTTGGCGGAGCTGGTCAAACGGGCAAAACGCATAAAACTCGGAAACGGTTTTCATGCTGAGACA
GAAAGCGGTCCGCTTATTTCGGCGGAGCACAGGGCAAAGGTAGAAAAATATGTAGAGATCGGAATAGAGGAAGGCGCGAA
GCTGGAGACAGGAGGCAAACGCCCGGAAGATCCTGAGCTTCAAAACGGCTTTTTCTATGAACCTACTATTTTCTCAAACT
GTAATTCTGACATGAGAATCGTTCAGGAAGAGGTTTTCGGTCCTGTATTGACAGTCGAAACCTTCAGCTCTGAAGAAGAG
GTAATCGAGCTTGCGAATGATACCATCTATGGCTTGGCTGGAGCGGTATGGTCAAAAGACATTGAAAAGTGCGAACGGGT
AGCAGCCCGCTTGAGAATGGGAACCGTTTGGATCAACGATTTTCATCCGTACTTTGCACAAGCGCCATGGGGCGGATATA
AGCAATCCGGGTTCGGACGCGAGCTTGGAAAAATAGGCCTTGAAGAATACACAGAAGTCAAACATGTATACCGCAATACA
AAACCGGCAGCGGTTAACTGGTTTAATTCATAA

Protein sequence :
MSQTLFIDGEWISAEKEQIRSIINPFNQEEIATVSEGGREDAIKAIAAARRAFDKGEWSSLSGLERGKIVLKIAELIRRD
LEELAELESLDTGKTLEESKADMDDIANVFQYYAGLADKDGGEIISSPIPDSESKIIREPIGVCGQITPWNYPLLQASWK
IAPALAAGNTIVMKPSEITPLTTIKVFKLMEEAGVPKGVANLVLGPGATVGDELAVNKDVDLISFTGGIETGKKIMRAAS
GNVKKIALELGGKNPNIVFKDADLEVAVDQALNAVFFHAGQVCSAGSRLLVEDAIHDQFLAELVKRAKRIKLGNGFHAET
ESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPEDPELQNGFFYEPTIFSNCNSDMRIVQEEVFGPVLTVETFSSEEE
VIELANDTIYGLAGAVWSKDIEKCERVAARLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEVKHVYRNT
KPAAVNWFNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-70 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
gbsA YP_007535093.1 glycine betaine aldehyde dehydrogenase, NAD+-dependent GbsA VFG0082 Protein 6e-71 42