Gene Information

Name : guaA (B649_01495)
Accession : YP_007527308.1
Strain : uncultured Sulfuricurvum sp. RIFRC-1
Genome accession: NC_020505
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 295496 - 297040 bp
Length : 1545 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
TTGAAAGATGTCAATATTATCGTTCTTGATTTTGGTTCACAGTACACACAGTTGATCGCACGACGTTTGCGCGAAGATAA
AGTCTATTGTGAGGTACTTCCTTACCACACTAAAATCGATGCTATTAAAGCAAAAAATCCAAAAGGTATCATTCTCAGCG
GTGGACCTTCATCCGTTTATAACAAAGATGCGTATACTGTCGATCAAGGTGTTTACGCACTTGGAATCCCTGTTCTTGGG
ATTTGTTACGGTATGCAGCGTATCGCGGTTGATTTCGGCGGTTCGGTTATCCGAAGTGATCATCACGAATACGGAAAAGC
GGAACTTACCATCGATATGACACAGCACTCAATACTCTTCGAGGGGTGCGAAGACGAACGCGCCGTGTGGATGAGCCATT
CGGACAAAGTGGATGTATTGCCGGAAGGCTTTGTCCCTATCGCGTATTCGCCAAACTCCCCGTATGCAGCCATCGCAAAT
GAAGCAAAAATGATCTACGCGATGCAATATCACCCGGAGGTAAACCACTCTGAAGAGGGGTATTTGATGCTTCGCAATTT
TGCACGCAAAATTTGCGGCATTACCGAAAAATGGGACATGGGACATTTTCTCAAAGAGCAAATCGTGAAAATTCGCGCCC
AAGTGGGTGAGGGGAAAGTACTTTGCGCACTCAGCGGAGGGGTGGACTCTTCGGTCGTTGCGGCATTGTTGTACGAAGCG
ATCGGCGATCAGTTGATCCCGGTTTTCGTCGATAACGGATTATTGCGCAAGGGGGAACGTGACTCGGTTGAAAATATTTT
CAAAGTTCATCTCAAGGTACCTCTCGTCGTTGCCGATGCATCGGAAAATTTCCTCGGCAAGCTTGCCGGTGTGACGGATC
CTGAGACGAAACGAAAAATTATCGGACACACCTTTATCGAAGTGTTTGAAGCGGAAGCGAAAAAGCATGACGGTATTAAA
TTCTTGGCGCAGGGGACATTGTATCCCGACGTTATCGAATCGGTTTCCGTTAACGGCCCATCGGTGACGATCAAAAGCCA
TCACAATGTCGGCGGACTCCCTGACTGGATGGATTTCGAGTTGATTGAACCTCTCCGTGATTTGTTCAAAGACGAAGTAC
GTAAACTCGGGCTTGAACTCGGATTGCCGGATTCATTGGTTAACCGTCATCCGTTCCCGGGACCGGGTCTTGGTATCCGT
ATCATGGGTGAGGTTAACAAACCGGATTTGAATCTTTTACGTGAAGCCGATGCGATTTTGCTTGATGAACTCAAAGCGAG
TGGCTATTACACCAAAACATGGCAAGCATTTGCGGTACTCCTGAACGTCAAATCAGTCGGCGTTATGGGAGATAACCGTA
CCTATGACAACACCGTTTGTGTCCGTGTTGTGGAAGCGGTGGATGGGATGACGGCAACGTTTGCCCATCTTCCTCACACC
TTGTTGGAACGTATCAGCCGCCGTATCATTAACGAAGTTGATGGAATCAATCGTGTCGTATACGATATCAGTTCCAAGCC
CCCTGCTACGATCGAGTGGGAATAA

Protein sequence :
MKDVNIIVLDFGSQYTQLIARRLREDKVYCEVLPYHTKIDAIKAKNPKGIILSGGPSSVYNKDAYTVDQGVYALGIPVLG
ICYGMQRIAVDFGGSVIRSDHHEYGKAELTIDMTQHSILFEGCEDERAVWMSHSDKVDVLPEGFVPIAYSPNSPYAAIAN
EAKMIYAMQYHPEVNHSEEGYLMLRNFARKICGITEKWDMGHFLKEQIVKIRAQVGEGKVLCALSGGVDSSVVAALLYEA
IGDQLIPVFVDNGLLRKGERDSVENIFKVHLKVPLVVADASENFLGKLAGVTDPETKRKIIGHTFIEVFEAEAKKHDGIK
FLAQGTLYPDVIESVSVNGPSVTIKSHHNVGGLPDWMDFELIEPLRDLFKDEVRKLGLELGLPDSLVNRHPFPGPGLGIR
IMGEVNKPDLNLLREADAILLDELKASGYYTKTWQAFAVLLNVKSVGVMGDNRTYDNTVCVRVVEAVDGMTATFAHLPHT
LLERISRRIINEVDGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-142 57
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-142 57
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-142 57
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-124 53