Gene Information

Name : metB (BN159_3448)
Accession : YP_007521954.1
Strain : Streptomyces davawensis JCM 4913
Genome accession: NC_020504
Putative virulence/resistance : Resistance
Product : Cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 3900336 - 3901490 bp
Length : 1155 bp
Strand : -
Note : -

DNA sequence :
ATGAGCGACAGGCACATCAGTCAGCACTTCGAGACGCTCGCCATCCACGCGGGCAACACGGCGGACCCCCTCACCGGTGC
GGTCGTCCCGCCCATCTACCAGGTCTCGACCTACAAGCAGGACGGCGTCGGCGGCCTGCGCGGCGGCTACGAGTACAGCC
GTAGCGCCAACCCCACCAGGACCGCCCTGGAAGAGAACCTCGCCGCCCTGGAGGGCGGCCGTCGCGGGCTCGCGTTCGCA
TCCGGTCTTGCGGCCGAGGACTGCCTGCTGCGTACGCTGCTCAGCCCCGGCGACCACGTGGTCATCCCGAACGACGCGTA
CGGCGGCACCTTCCGGCTCTTCGCGAAGGTCGTCGCCCGCTGGGGCGTGGAGTGGTCGGTCGCCGACACCAGCGACCCCG
CCGCCGTCCGGGCGGCCATCACCCCGAAGACCAAGGCCGTGTGGGTGGAGACCCCCTCCAACCCGCTGCTCGGCATCACC
GACATCGCCACGGTCGCCCAGATCGCCCGGGACGCGGGCGCGAAGCTCGTCGTCGACAACACCTTCGCCACGCCCTACCT
CCAGCAGCCGCTGTCGCTCGGCGCCGATGTCGTGGTCCACTCCCTGACCAAGTACATGGGCGGTCACTCCGACGTCGTCG
GCGGCGCGCTGATCGTGAGCGACGAGGGCCTCGGCGAGGAACTGGCCTTCCATCAGAACGCGATGGGCGCGGTCGCCGGG
CCCTTCGACTCCTGGCTCGTGCTGCGCGGCACCAAGACGCTTTCGGTGCGCATGGACCGGCACAGCGAGAACGCCACCAA
GGTCGCCGACATGCTCTCCCGGCACGCGCGCGTGACGAAGGTGCTCTACCCGGGGCTGCCCGAGCACCCCGGCCACGAGG
TCGCCGCCAAGCAGATGAAGGCGTTCGGCGGCATGGTCTCCTTCCAGGTGGCGGGCGGCGAGGAGGCGGCCGTCGAGGTC
TGCAACCGCGCCAAGGTGTTCACGCTCGGCGAGTCCCTCGGCGGTGTCGAGTCGCTGATCGAGCACCCGGGCCGCATGAC
GCACGCCTCGGCCGCCGGTTCGGCCCTCGAGGTGCCGGCCGATCTCGTCCGCCTGTCCGTGGGCATCGAGAACGTGGAGG
ACCTGCTGGAGGACCTTCAGCAGGCGCTCGGCTGA

Protein sequence :
MSDRHISQHFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFA
SGLAAEDCLLRTLLSPGDHVVIPNDAYGGTFRLFAKVVARWGVEWSVADTSDPAAVRAAITPKTKAVWVETPSNPLLGIT
DIATVAQIARDAGAKLVVDNTFATPYLQQPLSLGADVVVHSLTKYMGGHSDVVGGALIVSDEGLGEELAFHQNAMGAVAG
PFDSWLVLRGTKTLSVRMDRHSENATKVADMLSRHARVTKVLYPGLPEHPGHEVAAKQMKAFGGMVSFQVAGGEEAAVEV
CNRAKVFTLGESLGGVESLIEHPGRMTHASAAGSALEVPADLVRLSVGIENVEDLLEDLQQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-82 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-83 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-66 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_007521954.1 Cystathionine gamma-synthase BAC0207 Protein 2e-67 45