Gene Information

Name : pyk1 (BN159_2987)
Accession : YP_007521493.1
Strain : Streptomyces davawensis JCM 4913
Genome accession: NC_020504
Putative virulence/resistance : Virulence
Product : Pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 3403829 - 3405259 bp
Length : 1431 bp
Strand : +
Note : -

DNA sequence :
ATGCGCCGTTCGAAAATCGTCTGTACTCTCGGCCCCGCGGTCGACTCCCATGAACAGCTGGTGTCGCTGATCGAGGCGGG
CATGAATGTGGCCCGCTTCAACTTCAGCCACGGCTCGCACGAAGAGCACCAGGGGCGGTACGACCGCGTCCGGGCCGCCG
CCCAGGAGACCGGGCGGGCCATCGGTGTGCTCGCCGACCTCCAGGGCCCCAAGATCCGTCTGGAGACCTTCGCCGAGGGT
CCGGTGGAGCTGGAGCGTGGTGACGAGTTCGTCATCACCACCGAGGACATCCCGGGTGACAAGCAGATCTGCGGAACCAC
CTACAAGGGCCTGCCGGGCGATGTCTCGCGCGGCGACCAGATCCTCATCAACGACGGCAACGTCGAGCTGAAGGTCCTGG
ACGTCGAGGGCCCCCGGGTCAAGACGATCGTCATCGAGGGCGGTGTCGTCTCCGACCACAAGGGCATCAACCTGCCGGGC
GCGGCCGTGAACGTGCCGGCCCTGTCCGAGAAGGACGTCGAGGACCTGCGGTTCGCGCTGCGCATGGGCTGCGACATGGT
CGCGCTGTCCTTCGTGCGGGACGCCGACGACGTGCAGGACGTCCACAAGGTCATGGACGAGGTCGGCCGCCGCGTCCCGG
TCATCGCCAAGGTGGAGAAGCCGCAGGCGGTGCAGAACATGGAGGACGTCGTCGCGGCGTTCGACGCCGTGATGGTGGCC
CGTGGCGACCTGGCCGTCGAGTACCCGCTCGAAAAGGTCCCCATGGTGCAGAAGCGGCTCATCGAGCTGTGCCGCCGCAA
CGCCAAGCCGGTGATCGTGGCGACCCAGATGATGGAGTCGATGATCACCAACTCCCGCCCGACCCGCGCCGAGGCCTCCG
ACGTGGCCAACGCGATCCTGGACGGCGCCGACGCGGTGATGCTGAGCGCGGAGTCCTCGGTCGGCGCCTACCCGATCGAG
ACCGTCAAGACGATGTCGAAGATCGTCCAGGCGGCCGAGCAGGAGCTGCTCGCCAAGGGGCTTCAGCCGCTCGTCCCGGG
CAAGAAGCCGCGTACGCAGGGCGGTTCGGTCGCCCGCGCGGCCTGCGAGATCGCCGACTTCCTCGGCGGCAAGGGCCTGA
TCGCCTTCACCAAGTCCGGTGACACCGCCCGCCGGCTGTGCCGCTACCGCGCCGCCCAGCCGATCCTGGCCTTCACCACC
GACGAGGCCACCCGCAACCAGCTCACCCTCAGCTGGGGCGTGGAGTCGCACGTCGTGCCGTTCGTCAACAGCACCGACGA
GATGGTCGACCTGGTCGACGGTGAAGTGATCAAGCTGGGCCGCTTCAACGAGGGCGACGTCCTCATCATCACGGCCGGCT
CGCCCCCCGGCGTCCCCGGCACCACCAACATGGTCCGCGTCCACCACCTCGGCGGCGGCGGCATCAACTGA

Protein sequence :
MRRSKIVCTLGPAVDSHEQLVSLIEAGMNVARFNFSHGSHEEHQGRYDRVRAAAQETGRAIGVLADLQGPKIRLETFAEG
PVELERGDEFVITTEDIPGDKQICGTTYKGLPGDVSRGDQILINDGNVELKVLDVEGPRVKTIVIEGGVVSDHKGINLPG
AAVNVPALSEKDVEDLRFALRMGCDMVALSFVRDADDVQDVHKVMDEVGRRVPVIAKVEKPQAVQNMEDVVAAFDAVMVA
RGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIE
TVKTMSKIVQAAEQELLAKGLQPLVPGKKPRTQGGSVARAACEIADFLGGKGLIAFTKSGDTARRLCRYRAAQPILAFTT
DEATRNQLTLSWGVESHVVPFVNSTDEMVDLVDGEVIKLGRFNEGDVLIITAGSPPGVPGTTNMVRVHHLGGGGIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-74 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-73 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-73 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-74 42
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-62 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk1 YP_007521493.1 Pyruvate kinase VFG0479 Protein 4e-74 42