Gene Information

Name : metB2 (lilo_0718)
Accession : YP_007508045.1
Strain : Lactococcus lactis IO-1
Genome accession: NC_020450
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 769715 - 770857 bp
Length : 1143 bp
Strand : +
Note : K01760 cystathionine beta-lyase

DNA sequence :
ATGACAAGTTTAAAAACGAAAGTAATTCATGGTGGTATTTCAACAGACAAGACAACAGGAGCAGTATCTGTTCCGATTTA
TCAAACGTCAACTTATAAACAAAACGGACTTGGACAACCTAAAGAATACGAATATTCACGTTCTGGAAATCCAACGCGTC
ATGCCTTGGAAGAATTAATTGCAGATTTAGAAGGTGGTGTTCAAGGATTTGCATTTAGTTCAGGACTTGCTGGAATTCAT
GCGGTTCTTTCGCTTTTTTCTGCAGGAGATCATATCATTTTAGCTGATGATGTTTATGGTGGAACTTTCCGTTTGATGGA
TAAAGTGCTGACAAAGACAGGGATTATTTATGATTTAGTTGATTTGAGTAATCTTGATGACTTGAAAGCAGCTTTTAAGG
AAGAAACGAAAGCTGTTTATTTTGAAACTCCTTCAAATCCTTTATTAAAAGTTTTGGACATTAAGGAAATTTCAGCAATT
GCTAAAGCTCATGATGCCTTAACACTGGTGGATAATACCTTTGCGACACCATATTTACAACAACCAATTGCTTTAGGAGC
TGATATTGTTTTGCATTCCGCAACGAAATATTTAGGTGGACATTCAGATGTAGTAGCAGGACTAGTCACAACCAATTCAA
AAGAACTCGCTAGCGAAATTGGCTTTTTACAAAATTCAATTGGAGCAGTTCTTGGACCACAAGACAGCTGGTTAGTGCAA
AGAGGTATTAAAACACTTGCGCTTCGGATGGAGGCTCATTCGGCAAATGCTCAAAAAATTGCTGAGTTTTTAGAAACTTC
TAAAGCCGTCTCAAAAGTTTATTATCCGGGTCTTAATAGCCACCCGGGGCATGAAATTGCTAAAAAACAAATGTCTGCCT
TTGGAGGGATGATTTCATTTGAATTAACGGATGAAAATGCCGTCAAAGATTTTGTTGAAAACTTGAGCTATTTTACGTTG
GCTGAATCACTAGGTGGCGTTGAATCTTTAATTGAAGTGCCAGCAGTGATGACTCATGCTTCTATTCCAAAAAAACTTCG
TGAAGAAATTGGGATTAAGGATGGCCTAATTCGTCTATCAGTAGGGGTTGAAGCAATTGAAGATTTACTGACAGATATCG
AAAATGCATTTGAAAAAAAATAA

Protein sequence :
MTSLKTKVIHGGISTDKTTGAVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH
AVLSLFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLDDLKAAFKEETKAVYFETPSNPLLKVLDIKEISAI
AKAHDALTLVDNTFATPYLQQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLVQ
RGIKTLALRMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMISFELTDENAVKDFVENLSYFTL
AESLGGVESLIEVPAVMTHASIPKKLREEIGIKDGLIRLSVGVEAIEDLLTDIENAFEKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-96 55
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-95 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-74 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB2 YP_007508045.1 cystathionine beta-lyase BAC0207 Protein 5e-71 44