Gene Information

Name : guaA (CLOAM0898)
Accession : YP_001740978.1
Strain : Candidatus Cloacamonas acidaminovorans Evry
Genome accession: NC_020449
Putative virulence/resistance : Unknown
Product : GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1048451 - 1049986 bp
Length : 1536 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3894345, 1312531; Product type e : enzyme

DNA sequence :
ATGCATAATAAAGTTTTGATTTTAGATTTTGGTTCTCAATATACGCAATTGATAGCCCGAAAAGTGCGTTCTTTAAACAT
CTACTGCGAGATTCAACCCTATCAGATAAGTTTAGAACAAATACAATCCTTTGCTCCGCAAGCAATTATACTTTCAGGAA
GTCCATCTAGTTCAAGTAAAAAAAATTCACCCAAGCCGGAGGAAGGAATTTGGCAACTTGGCATTCCCATTTTGGGAATC
TGTTATGGAATGCAATTATTGGTAACTCATTATGGGGGAACAATTCTACCATCAGATAAAAGAGAATATGGCTCTGCAAT
ATTAAATATCATTAACCATAATGAATTACTTGCAGGATTGGGAGATAGGGAAGAGGTCTGGATGAGCCATAGTGACGCTG
TTTCCAGTTTACCCGAATGCTTTTCTGTTTTAGCAAAAACGGATCAATCCCCTTATGCTGTAATAGCTCATAAGGAATTA
CCTTTTTATGGCTTGCAGTTTCATCCGGAAGTAGCGAACACAAAAAACGGAATAAAAGTATTAGAGAATTTTCTGATTAG
GATTGGAAAAATAACTGCGAACTGGACTCCGAATGCCTTTATCAATGAAAATATTGAGAAAATAAGAAAACAGGTAGGCA
ACCAAAAAGTTCTATTGGGATTAAGTGGAGGGGTTGATTCTTCAGTTACTGCGGTTTTACTTTATAAAACAATCGGAAAT
CAGCTCCTGCCTATTTTTGTGGATACCGGATTGATGCGTTACAAGGAAGCAGAAAGAGTAAAACAGACCTTTTCCGCTTA
TCCTGATTTAAATATTCGCTATGTGGATGCCAGTAAAACATTTATCTCCAAACTAAAAGGAATTACCGATCCGGAAACAA
AACGGAAAATAATCGGCAACACCTTTATAGAGGTCTTTGAAAAGATAGCCGGAGAATATGAAGAGGTGCATTTTTTAGCA
CAGGGAACTCTCTATCCAGATGTAATTGAAAGTGCCACTTTTACGGGAATGACAGCAAAGATTAAAAGTCATCATAATGT
AGGTGGTTTACCGGAAAAAATGAATTTAGCTTTAATTGAACCCTTAAGAGAACTTTTTAAGGATGAGGTCAGAGAAGTAG
GAACTTTGCTTGGTTTACCTGAATCCATTATCCAAAGACATCCCTTTCCGGGACCAGGTTTAGCCGTTAGAATTATAGGA
GAAGTAAATGCAGAAAAAGTCCGTCTGCTTCAGCTTGCGGATGAGATATTTATAAGCGAATTACAAAAAAACGGACTTTA
TAATACAACCTGGCAGGCATTTGCCGTTCTTTTACCTATTAGAACGGTTGGAGTAATGGGTGATGAACGCAGTTATGATC
AGGTTTGTGCTTTAAGAGCTGTAGATAGTATTGATGGTATGACTGCTAATTTTACTCAGTTACCAATGTGGTTTTTACAG
AAAGTTGCTAATCGCATTTGTAATGAAGTGAAAGGTATCAGCAGGGTGGTTTATGATATTTCCTCCAAGCCACCTGCTAC
CATTGAATGGGAATAA

Protein sequence :
MHNKVLILDFGSQYTQLIARKVRSLNIYCEIQPYQISLEQIQSFAPQAIILSGSPSSSSKKNSPKPEEGIWQLGIPILGI
CYGMQLLVTHYGGTILPSDKREYGSAILNIINHNELLAGLGDREEVWMSHSDAVSSLPECFSVLAKTDQSPYAVIAHKEL
PFYGLQFHPEVANTKNGIKVLENFLIRIGKITANWTPNAFINENIEKIRKQVGNQKVLLGLSGGVDSSVTAVLLYKTIGN
QLLPIFVDTGLMRYKEAERVKQTFSAYPDLNIRYVDASKTFISKLKGITDPETKRKIIGNTFIEVFEKIAGEYEEVHFLA
QGTLYPDVIESATFTGMTAKIKSHHNVGGLPEKMNLALIEPLRELFKDEVREVGTLLGLPESIIQRHPFPGPGLAVRIIG
EVNAEKVRLLQLADEIFISELQKNGLYNTTWQAFAVLLPIRTVGVMGDERSYDQVCALRAVDSIDGMTANFTQLPMWFLQ
KVANRICNEVKGISRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-122 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-122 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-122 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-109 48