Gene Information

Name : cadA (Nmlp_3315)
Accession : YP_007488134.1
Strain : Natronomonas moolapensis 8.8.11
Genome accession: NC_020388
Putative virulence/resistance : Resistance
Product : P-type transport ATPase (probable substrate zinc/cadmium)
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.-
Position : 2279823 - 2282090 bp
Length : 2268 bp
Strand : +
Note : -

DNA sequence :
ATGAGCACGGAACGCCTCGAACTGTCGGTGCCCGACATGGACTGTTCGTCCTGTGCGGGGAAAGTCGACGCCGCCCTGGC
TGACGCCGAGGGGGTCCACGGGGTCGAGACGCGGCCGACGGCCGGCGTCGCGGTCGTCGAGTTCGACCCCGGGGCGATCG
ACGCGGACGGGATCGTCGGCCGCGTCGAGGCCGCGGGCTACGGCGTGGCCGGGACCGACGGGATGGCCTCCGGGGCGGCC
GTCTGGACTAGCCGTCGGGCCTACGCCACCTACGCCGGCGCGGTCGCGATGCTCGCCGGATTCGTCGTCCTCTGGGGCCC
CGTGGCCGACCCGGCCCTCTTCGATATCGGCCGGGAGACGGCCCGCAGCGACGTCCTGTTCGTCCTCGGGGCCGCCGTCG
CCGGCGGCCCGGTCGCCCGCGCGGGGCTCCGGTCGGCGCGCCTCCGGGAGCTCGACATCGATCTCCTGATGGGGACGGCG
ATCCTCTCGGCGATGGCCGTCGGTTACTACGTCGAGGCGGCGACACTCGCGGTGCTTTTCAGCCTCGCGGAGCTGCTCGA
AGCACACGCGATGGATCGGACCCGCGAGTCGATCCGGGAACTGCTCGCGCTCTCGCCCGACACGGCGACGGTCAAACGGG
ATGGCGAGGAGACGTCGGTTCCCGCCGCGAGCGTCCGAACGGGCGAGGTCGTCGTCGTCCGCCCGGGCGAGCGGATCCCC
GTCGACGGCGATGTCCTCGAGGGCGAATCAGCGGTCGACGAGTCCCCGATCACCGGCGAGTCGGTCCCCGTCGACAAGAG
CGTCGGCGACGAAGTGTACGCCGGCAGCGTCGCCGAGGGTGGTTACATCGAGATCGAGGCGACCGCCGCGGGCGACGAGA
CGACACTGTCTCGGGTGGTCGACCTCGTCGAGAGCGCCGAGTCCAGGCGGACAGACGCCGAACGACTGGTCGATCGCTTT
GCGGGCTATTACACCCCGGTCGTCGTCGCCGGCGCGGTGGGGACCGTTTTGATCCCACCGTTGTTCTTCGGCGGCGCGTG
GGGCACGTGGTTCGTCCGGGGGCTGACGCTGCTCGTCGTCGCCTGCCCCTGTGCGTTCGTCATCTCGACGCCGGTCACGG
TCGTCTCGGGGCTGACGAGCGCGGCCCGCAACGGCGTCCTGATAAAGGGTGGCGACCACCTCGAGCGGATGGGCGAGGTC
GACACCGTCGCCTTCGACAAGACGGGGACGCTGACGACCGGCGACCTCGCCGTGACCGACGTGGTGCCGGCGGCCGGCCA
CGACGCGGCCGACGTCCTCGCGACCGCCGCCGGCGTCGAGCGCCACAGCGAGCACCCCATAGGGGCTGCCATCGTCGAAC
GCGCCCGCGAGGCCGGCGTCGACCGCCCCGAGGCCAGCGACTTCGAGAGCCTCACCGGACGGGGGGTCCGTGCCGACCTC
GGCGGGACGCGCTACGTCGGCAAGCCCGAGTTGTTCGCCGAGTTGGGCCACGACCTCGGGCACACGCACCTGCGGACCGA
CGGCGGGGCGGCCGCGGCCGAAGCCGACGGGGCGGCCGTCGGCGACCCGGCCTGCGAGCGCCCCGGTTGCGTCGATCTCC
GGGCCGGCACCATCGCCGGGTTGCAGTCCGACGGCAAGACGGCCGTCCTCGTCGGCACCGAGACCGAACTGTACGGCGTC
GTCGCCGTCGCCGACACCGTCCGTCCCGAGGCACGGGCGGTCGTCGCCGCGCTCGCCGACGCCGGCGTCCAGACGGTGAT
GCTCACCGGCGACAACGAGCGGACCGCCCGGGCCGTCGGCGACGCCGTCGGGATCGGGACGGTCCACGCGGACCTCCTGC
CCGAGGCGAAACTCGACGCGATCGAGGGGCTCATCGAGGACGGCACCGTCGCGATGGTCGGCGACGGTATCAACGACGCC
CCCGCGTTGGCCCGCGCCGACGTCGGGGTCGCGATGGGTGCCGCCGGCACCGACGCGGCGCTGGAGACGGCCGACATCGC
GCTCATGGCCGACGACCTGGGTGGCGTCCCCTACAGCCTCCGGTTGGCCCGCGGTGCCAACGACATCATCAAACAGAACA
TCGGCGCGAGCCTCGCCGTGAAGGCGATTCTCGCCGTCGGCGCGCCGCTGGGCTACGTCTCGGTCATCGTCGCCGTCCTC
GTCGGCGACATGGGGATGAGCCTCGGCGTGACGTCGAACGCGTTCCGCCTCGGCCGGGTCGATCCCGCGGAGTACGGCCT
CGAGGGAGACGAAGCGCGGATCGACTGA

Protein sequence :
MSTERLELSVPDMDCSSCAGKVDAALADAEGVHGVETRPTAGVAVVEFDPGAIDADGIVGRVEAAGYGVAGTDGMASGAA
VWTSRRAYATYAGAVAMLAGFVVLWGPVADPALFDIGRETARSDVLFVLGAAVAGGPVARAGLRSARLRELDIDLLMGTA
ILSAMAVGYYVEAATLAVLFSLAELLEAHAMDRTRESIRELLALSPDTATVKRDGEETSVPAASVRTGEVVVVRPGERIP
VDGDVLEGESAVDESPITGESVPVDKSVGDEVYAGSVAEGGYIEIEATAAGDETTLSRVVDLVESAESRRTDAERLVDRF
AGYYTPVVVAGAVGTVLIPPLFFGGAWGTWFVRGLTLLVVACPCAFVISTPVTVVSGLTSAARNGVLIKGGDHLERMGEV
DTVAFDKTGTLTTGDLAVTDVVPAAGHDAADVLATAAGVERHSEHPIGAAIVERAREAGVDRPEASDFESLTGRGVRADL
GGTRYVGKPELFAELGHDLGHTHLRTDGGAAAAEADGAAVGDPACERPGCVDLRAGTIAGLQSDGKTAVLVGTETELYGV
VAVADTVRPEARAVVAALADAGVQTVMLTGDNERTARAVGDAVGIGTVHADLLPEAKLDAIEGLIEDGTVAMVGDGINDA
PALARADVGVAMGAAGTDAALETADIALMADDLGGVPYSLRLARGANDIIKQNIGASLAVKAILAVGAPLGYVSVIVAVL
VGDMGMSLGVTSNAFRLGRVDPAEYGLEGDEARID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-107 43
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 8e-107 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-107 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_007488134.1 P-type transport ATPase (probable substrate zinc/cadmium) BAC0298 Protein 8e-96 45
cadA YP_007488134.1 P-type transport ATPase (probable substrate zinc/cadmium) BAC0124 Protein 3e-75 42
cadA YP_007488134.1 P-type transport ATPase (probable substrate zinc/cadmium) BAC0100 Protein 3e-62 41