Gene Information

Name : H175_ch2874 (H175_ch2874)
Accession : YP_007479335.1
Strain : Bacillus thuringiensis IS5056
Genome accession: NC_020376
Putative virulence/resistance : Virulence
Product : Aldehyde dehydrogenase in 4-hydroxyproline catabolic gene cluster
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 2855406 - 2856890 bp
Length : 1485 bp
Strand : -
Note : -

DNA sequence :
ATGTTAAAGACAAATATTGAGCTGAAACCAAAAGTGGAAGCGTTTTTAAATGAAGAAATTAAAATGTTTATTAATGGCGA
ATTTGTTTCTGCTATTGGCGGAAAGACGTTTGAAACATACAATCCAGCAACAGAAGATGTTCTAGCAGTCGTATGTGAAG
CGCAAGAAGAGGATATTGATGCTGCAGTAAAAGCAGCAAGATCTGCATTTAAATCTGGTCCGTGGGCAGAAATGACTACT
GCTGAAAGAGCGCATCTTATTTATAAATTAGCAGATTTAATTGAAGAACATAGAGAAGAATTAGCGCAACTAGAAGCTTT
AGATAATGGAAAGCCATATCAAGTAGCACTTGATGATGATATTTCAGCGACTGTAGAAAATTATCGTTATTACGCAGGAT
GGGCTACAAAAATTATTGGGCAAACAATCCCAATTTCAAAAGATTACTTAAATTACACGAGACATGAACCTGTAGGTGTT
GTAGGTCAGATTATTCCGTGGAACTTTCCGCTCGTTATGTCTTCTTGGAAAATGGGAGCTGCACTGGCGACAGGTTGTAC
GATCGTATTAAAACCAGCAGAGCAAACACCTTTATCCTTACTATATACAGCAAAACTCTTTAAAGAGGCTGGATTTCCAA
ACGGTGTTGTAAACTTTGTACCAGGCTTTGGTCCTGAAGCAGGAGCAGCAATTGTAAATCATCATGACATTGATAAAGTT
GCTTTTACAGGATCTACTGTTACAGGAAAGTATATTATGCGTCAGTCTGCAGAAATGATTAAGCATGTAACGTTAGAGCT
TGGCGGCAAATCACCAAATATCATTTTAGAAGATGCGGACTTGGAAGAAGCAATTAATGGTGCATTCCAAGGTATTATGT
ATAATCACGGTCAAAATTGTAGCGCAGGATCACGTGTATTTGTTCATCGTAAACATTATGAAACTGTAGTAGATGCACTT
GTGAAAATGGCGAACAACGTAAAACTTGGAGCAGGTATGGAGAAAGGAACGGAAATGGGTCCACTCGTATCTAAGAAACA
ACAAGAGCGTGTGTTACATTATATTGAGCAAGGGAAGAAAGAAGGTGCTACAGTTGCGGCTGGTGGCGAACGTGCGCTTG
AAAAAGGTTATTTCGTTAAACCAACTGTATTCACAGATGTTACAGACGATATGACAATCGTTAAGGAAGAAATATTTGGA
CCAGTTGTTGTTGTACTTCCATTTGATTCGACAGAAGAAGTAATTGAACGAGCGAACAACTCATCCTATGGCCTTGCTGC
GGGTGTATGGACGCAAAATATCAAAACGGGTCATCAAGTGGCAAATAAATTAAAAGCAGGAACAGTGTGGATTAATGATT
ATAACTTAGAAAATGCAGCTGCACCATTTGGTGGATACAAACAATCTGGTATTGGCCGCGAATTAGGTTCATATGCGCTT
GATAATTATACAGAAGTGAAAAGTGTTTGGGTAAATATAAAGTAA

Protein sequence :
MLKTNIELKPKVEAFLNEEIKMFINGEFVSAIGGKTFETYNPATEDVLAVVCEAQEEDIDAAVKAARSAFKSGPWAEMTT
AERAHLIYKLADLIEEHREELAQLEALDNGKPYQVALDDDISATVENYRYYAGWATKIIGQTIPISKDYLNYTRHEPVGV
VGQIIPWNFPLVMSSWKMGAALATGCTIVLKPAEQTPLSLLYTAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKV
AFTGSTVTGKYIMRQSAEMIKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQNCSAGSRVFVHRKHYETVVDAL
VKMANNVKLGAGMEKGTEMGPLVSKKQQERVLHYIEQGKKEGATVAAGGERALEKGYFVKPTVFTDVTDDMTIVKEEIFG
PVVVVLPFDSTEEVIERANNSSYGLAAGVWTQNIKTGHQVANKLKAGTVWINDYNLENAAAPFGGYKQSGIGRELGSYAL
DNYTEVKSVWVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-90 45
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-86 41
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-79 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-87 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-87 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-87 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-86 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
H175_ch2874 YP_007479335.1 Aldehyde dehydrogenase in 4-hydroxyproline catabolic gene cluster VFG0082 Protein 2e-86 41