Gene Information

Name : guaA (CFSAN001992_21000)
Accession : YP_007473910.1
Strain : Salmonella enterica CFSAN001992
Genome accession: NC_020307
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 4353958 - 4355535 bp
Length : 1578 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACGGAAAACATTCATAAGCATCGCATCCTCATTCTGGACTTCGGTTCTCAGTACACTCAACTGGTTGCGCGCCGCGT
GCGTGAGCTGGGCGTTTACTGCGAACTGTGGGCGTGGGATGTGACAGAAGCGCAAATTCGTGACTTCAACCCAAGCGGCA
TTATTCTTTCCGGCGGCCCGGAAAGCACCACCGAAGAAAACAGCCCGCGCGCGCCGCAGTATGTCTTTGAAGCAGGCGTG
CCGGTATTTGGCGTCTGCTACGGGATGCAGACTATGGCGATGCAGCTTGGTGGTCATGTAGAAGGTTCTAATGAGCGTGA
ATTTGGTTACGCGCAGGTCGAAGTATTGACCGACAGCGCGCTGGTTCGCGGTATTGAAGATTCCCTGACCGCCGACGGCA
AACCGCTGCTTGACGTGTGGATGAGCCACGGCGATAAAGTGACGGCGATTCCGTCCGACTTCGTGACCGTCGCCAGCACC
GAAAGCTGCCCGTTCGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTACAGTTCCACCCGGAAGTGACTCACAC
CCGCCAGGGTATGCGTATGCTGGAGCGTTTTGTGCGTGATATCTGCCAGTGTGAAGCCCTGTGGACGCCGGCGAAGATCA
TCGACGACGCTGTAGCCCGCATCCGCGAGCAGGTGGGCGACGACAAAGTAATCCTCGGTCTCTCCGGCGGCGTGGATTCC
TCCGTCACCGCAATGCTGCTGCACCGCGCGATCGGTAAAAATCTGACCTGTGTATTCGTCGATAACGGCCTGCTGCGCCT
CAACGAAGCCGAGCAGGTGATGGACATGTTTGGCGACCATTTTGGCCTGAATATCGTTCACGTACCGGCAGAAGAGCGTT
TCCTGTCCGCGTTGGCTGGTGAGAACGATCCGGAAGCCAAGCGTAAGATCATCGGTCGCGTTTTTGTGGAAGTGTTCGAT
GAAGAAGCGCTGAAACTGGAAGACGTGAAATGGCTGGCGCAGGGCACCATCTACCCTGACGTTATCGAATCTGCGGCGTC
TGCAACCGGTAAAGCGCACGTCATCAAATCTCACCACAATGTCGGCGGCCTGCCGAAAGAGATGAAGATGGGGCTGGTTG
AACCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGTAAGATTGGTCTGGAGCTGGGCCTGCCGTATGACATGCTGTATCGC
CATCCGTTCCCGGGGCCGGGCCTCGGCGTACGCGTACTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGCCGTGC
TGACGCCATCTTCATTGAAGAACTGCGTAAGGCGGATCTGTACGACAAAGTTAGTCAGGCGTTCACCGTCTTCCTGCCGG
TCCGTTCCGTAGGCGTCATGGGCGATGGTCGTAAGTACGATTGGGTGGTCTCTCTGCGTGCCGTCGAAACCATCGACTTT
ATGACCGCGCACTGGGCACATCTGCCGTATGACTTCCTGGGTCGTGTTTCCAACCGCATTATCAATGAAGTCAACGGGAT
TTCCCGTGTGGTGTATGACATTAGCGGTAAACCACCGGCTACCATTGAGTGGGAATAA

Protein sequence :
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEERFLSALAGENDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-110 48