Gene Information

Name : CFSAN001992_19045 (CFSAN001992_19045)
Accession : YP_007473525.1
Strain : Salmonella enterica CFSAN001992
Genome accession: NC_020307
Putative virulence/resistance : Virulence
Product : type III secretion system protein InvA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3950071 - 3952128 bp
Length : 2058 bp
Strand : +
Note : COG4789 Type III secretory pathway, component EscV

DNA sequence :
GTGCTGCTTTCTCTACTTAACAGTGCTCGTTTACGACCTGAATTACTGATTCTGGTACTAATGGTGATGATCATTTCTAT
GTTCGTCATTCCATTACCTACCTATCTGGTTGATTTCCTGATCGCACTGAATATCGTACTGGCGATATTGGTGTTTATGG
GGTCGTTCTACATTGACAGAATCCTCAGTTTTTCAACGTTTCCTGCGGTACTGTTAATTACCACGCTCTTTCGTCTGGCA
TTATCGATCAGTACCAGCCGTCTTATCTTGATTGAAGCCGATGCCGGTGAAATTATCGCCACGTTCGGGCAATTCGTTAT
TGGCGATAGCCTGGCGGTGGGTTTTGTTGTCTTCTCTATTGTCACCGTGGTCCAGTTTATCGTTATTACCAAAGGTTCAG
AACGCGTCGCGGAAGTCGCGGCCCGATTTTCTCTGGATGGTATGCCCGGTAAACAGATGAGTATTGATGCCGATTTGAAG
GCCGGTATTATTGATGCGGATGCCGCGCGCGAACGGCGAAGTGTACTGGAAAGGGAAAGCCAGCTTTACGGTTCCTTTGA
CGGTGCGATGAAGTTTATCAAAGGTGACGCTATTGCCGGCATCATTATTATCTTTGTGAACTTTATTGGCGGTATTTCGG
TGGGGATGACCCGCCATGGTATGGATTTGTCCTCCGCCCTGTCTACTTATACCATGCTGACCATTGGTGATGGTCTTGTC
GCCCAGATCCCCGCATTGTTGATTGCGATTAGTGCCGGTTTTATCGTGACTCGCGTAAATGGCGATAGCGATAATATGGG
GCGGAATATCATGACGCAGCTGTTGAACAACCCATTTGTATTGGTTGTTACGGCTATTTTGACCATTTCAATGGGAACTC
TGCCGGGATTCCCGCTGCCGGTATTTGTTATTTTATCGGTGGTTTTAAGCGTACTCTTCTATTTTAAATTCCGTGAAGCA
AAACGTAGCGCCGCCAAACCTAAAACCAGCAAAGGCGAGCAGCCGCTCAGTATTGAGGAAAAAGAAGGGTCGTCGTTGGG
ACTGATTGGCGATCTCGATAAAGTCTCTACAGAAACCGTACCGTTGATATTACTTGTGCCGAAGAGCCGGCGTGAAGATC
TGGAAAAAGCTCAACTTGCGGAGCGTCTACGTAGTCAGTTCTTTATTGATTATGGCGTGCGCCTGCCGGAAGTATTGTTA
CGCGATGGCGAGGGTCTGGACGATAACAGCATCGTATTGTTGATTAATGAGATCCGTGTTGAACAATTTACGGTCTATTT
TGATTTGATGCGAGTGGTAAATTATTCCGATGAAGTTGTTTCCTTTGGCATTAATCCAACAATCCATCAGCAAGGTAGCA
GTCAGTATTTCTGGGTAACGCATGAAGAGGGGGAGAAACTGCGGGAGCTTGGCTATGTGTTGCGGAACGCGCTTGATGAG
CTTTACCACTGTCTGGCGGTGACGCTGGCGCGCAACGTCAATGAATATTTCGGTATTCAGGAAACAAAACATATGCTGGA
CCAACTGGAAGCGAAATTTCCTGATTTACTTAAAGAAGTGCTCAGACATGCCACGGTACAACGTATATCTGAAGTTGTGC
AGCGTTTGTTAAGCGAACGTGTTTCCGTGCGTAATATGAAATTAATTATGGAAGCGCTCGCATTGTGGGCGCCAAGAGAA
AAAGATGTCATTAACCTTGTGGAGCATATTCGTGGGGCAATGGCGCGTTATATTTGCCATAAATTCGCCAATGGCGGCGA
ATTACGAGCAGTAATGGTATCTGCTGAAGTTGAGGATGTTATTCGCAAAGGGATCCGTCAGACCTCTGGCAGTACCTTCC
TCAGCCTTGACCCGGAAGCCTCCGCTAATTTGATGGATCTCATTACACTTAAGTTGGATGATTTATTGATTGCACATAAA
GATCTTGTCCTCCTTACGTCTGTCGATGTCCGTCGATTTATTAAGAAAATGATTGAAGGTCGTTTTCCGGATCTGGAGGT
TTTATCTTTCGGTGAGATAGCAGATAGCAAGTCAGTGAATGTTATAAAAACAATATAA

Protein sequence :
MLLSLLNSARLRPELLILVLMVMIISMFVIPLPTYLVDFLIALNIVLAILVFMGSFYIDRILSFSTFPAVLLITTLFRLA
LSISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK
AGIIDADAARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGISVGMTRHGMDLSSALSTYTMLTIGDGLV
AQIPALLIAISAGFIVTRVNGDSDNMGRNIMTQLLNNPFVLVVTAILTISMGTLPGFPLPVFVILSVVLSVLFYFKFREA
KRSAAKPKTSKGEQPLSIEEKEGSSLGLIGDLDKVSTETVPLILLVPKSRREDLEKAQLAERLRSQFFIDYGVRLPEVLL
RDGEGLDDNSIVLLINEIRVEQFTVYFDLMRVVNYSDEVVSFGINPTIHQQGSSQYFWVTHEEGEKLRELGYVLRNALDE
LYHCLAVTLARNVNEYFGIQETKHMLDQLEAKFPDLLKEVLRHATVQRISEVVQRLLSERVSVRNMKLIMEALALWAPRE
KDVINLVEHIRGAMARYICHKFANGGELRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANLMDLITLKLDDLLIAHK
DLVLLTSVDVRRFIKKMIEGRFPDLEVLSFGEIADSKSVNVIKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 99
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 99
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 99
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 99
ECs3731 NP_311758.1 EivA Not tested LIM Protein 2e-179 65
invA AAS66860.1 InvA Not tested SSR-2 Protein 7e-166 64
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-143 55
lssD AAO18050.1 LssD Virulence TTSS locus Protein 3e-95 41
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 1e-87 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN001992_19045 YP_007473525.1 type III secretion system protein InvA VFG0557 Protein 0.0 99
CFSAN001992_19045 YP_007473525.1 type III secretion system protein InvA VFG1006 Protein 7e-171 65
CFSAN001992_19045 YP_007473525.1 type III secretion system protein InvA VFG1780 Protein 1e-143 54
CFSAN001992_19045 YP_007473525.1 type III secretion system protein InvA VFG0064 Protein 3e-97 43
CFSAN001992_19045 YP_007473525.1 type III secretion system protein InvA VFG0384 Protein 1e-98 43
CFSAN001992_19045 YP_007473525.1 type III secretion system protein InvA VFG0198 Protein 5e-93 41