Gene Information

Name : CFSAN001992_12580 (CFSAN001992_12580)
Accession : YP_007472254.1
Strain : Salmonella enterica CFSAN001992
Genome accession: NC_020307
Putative virulence/resistance : Virulence
Product : Leukotoxin secretion protein D
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2559022 - 2560299 bp
Length : 1278 bp
Strand : -
Note : COG0845 Membrane-fusion protein

DNA sequence :
ATGAATAGAAGACAAAGCGATCATCTCATGATGATAATTATTTCTTTGACGATCTTAATTATTATCCTTACCTACTTTAT
AGAAATTAATTCAGTGGTTCATGGTCAGGGCGTTATCACTACTAAAGATAATGCTCAGTTAATATCTCTTTCTAAAGGAG
GAACGATACAAGATATTTATGTTGCCGAGGGTGATACTGTAAAAAAAGGAGAACTCCTTGCAAAGGTCGTTAACCTTGAT
CTGCAAAAAGAATATCAAAGGTATAGAACTCAAAAAGGGTATCTGGATAAAGATGTTAACGAAATATCCTTCATTCTTGA
TAAAGAAAATGAGAGTGGGTTGATTACCCTGGATGGCACCCGTTCTTTAAGCAATAAAGAGGTAAAAGCGAATATTGAAT
TAGTGCATAGTCAGATAAGAGCTAAAGAGTTAAAAAAAACCTCTCTTGATTCTGAGATTAGCGGATTACAAGAGAAGCTA
AGTTCGAAAGAAAAAGAACTAGCATTGCTTGCCGAAGAAATAAATATTCTTTCCCCACTGGTAAAAAAAGGAATTAGCCC
ATATACCAATTTTCTTAACAAGAAACAGGCGTATATAAAAGTTAAGTCTGAAATTAATGATATTGAAAGTAGTATCACTT
TAAAAAAAGATGATATTGAGCTGGTTGTTAATGATATTGAGGCGCTTAATAATGAATTGCGACTATCTTTATCTAAAATA
ATATCTAAAAATCTTCAGGAACTTGAGGTTGTTAACTCTACATTAAAAGTAATAGAGAAGCAGATAAATGAGGAGGATAT
CTATTCACCGGTTGACGGTGTAATTTATAAAATCAATAAAAGTGCCACTACTCATGGTGGTGTGATTCAGGCGGCGGACT
TACTTTTTGAAATAAAACCAAAAGTAAGGACTATGCTGGCCGATGTGAAAATACTACCCAAATACCGTGACCAAATATAT
GTAGATGAAGCCGTTAAGCTGGATGTCCAGTCAATTATCCAACCAAAGATAAAATCGTATAATGCGACTATCGATAATAT
TAGCCCTGATTCCTATGAGGAAAATACCGGAGGAACAATTCAGCGTTATTATAAAGTAATTATTGCATTCGATGTTAATG
AAGATGATTTACGGTGGTTAAAACCAGGTATGACTGTTGACGCCAGTGTAATTACCGGAAAACACAGCATTATGGAATAC
CTGTTATCTCCCTTGATGAAAGGCGTGGACAAAGCCTTTTCAGAACCAGTTAATACTAAACGATTAGATACACCTTGA

Protein sequence :
MNRRQSDHLMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVKKGELLAKVVNLD
LQKEYQRYRTQKGYLDKDVNEISFILDKENESGLITLDGTRSLSNKEVKANIELVHSQIRAKELKKTSLDSEISGLQEKL
SSKEKELALLAEEINILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELRLSLSKI
ISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKPKVRTMLADVKILPKYRDQIY
VDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGGTIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEY
LLSPLMKGVDKAFSEPVNTKRLDTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STM4260 NP_463125.1 cation efflux pump Not tested SPI-4 Protein 2e-175 100
spi4_D AAC26642.1 HLYD family secretion protein Virulence SPI-4 Protein 1e-175 100
siiD CAE11796.1 putative type-I secretion protein, putative inner membrane component Virulence SPI-4 Protein 1e-175 100
SC4139 YP_219126.1 membrane permease, cation efflux pump Not tested SPI-4 Protein 2e-175 100
STY4457 NP_458557.1 putative type-I secretion protein Not tested SPI-4 Protein 9e-175 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN001992_12580 YP_007472254.1 Leukotoxin secretion protein D VFG0580 Protein 8e-176 100