Gene Information

Name : CFSAN001992_12570 (CFSAN001992_12570)
Accession : YP_007472252.1
Strain : Salmonella enterica CFSAN001992
Genome accession: NC_020307
Putative virulence/resistance : Virulence
Product : Lipid A export ATP-binding/permease protein msbA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2540214 - 2542280 bp
Length : 2067 bp
Strand : -
Note : COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain

DNA sequence :
ATGGATAAAAAACTAGAACCTTATTATTTAAGTGCGGAAACGGCATTATCTATAGTGTCTAAAAAATTCAACATAAAAAT
TGACATCAAAGAAGATGATATAAATTTAAGATTTAAAAAGTACGACAGAAATAACACTGACGACTCTATACAAATGAAGA
ATTTCTTTTTGTCGTTAGGGCTTTCTCTACAGGATATATTATTTAATAATGGTGAGGATTTACTAAATGAGCCTATGCCG
ATTTTACTATTAACACCAGAAATGAAGTGGATGGTGTGTGTGAGTGGCGGGCAAAAAATAAAGTTGGTAAACGCGCGCGG
TGAACTCTGTTATGTTGAAATTGAAGATGAATATTTAAAAGAGTTATCTGCATTTAGTATACTACCTTTAAATAAAGTTG
TTGATAGTATAAGAGTAAAAAATATCATAAAAAACTCTTTATCGATGAACAAGATTTTTTATACTAAATACTTCTTTTCA
TCTCTTTTTATGGCAATTTTTGCGTTAACTATTCCAGTATTTAGTAATCTGTTCTATGATAAGCTTGTTCCAAGTGCTTC
GGTTTCATCTTTATTTGGCGTGGCTATAATTGTTGCTGTATTTATTGTTTTTGAGTTTATCCTTCGTACTTCGAAAGATA
TTTATCAGTCTATCACAGCAAGGCAGGATGACGTCGATATTGATATCGCATTTCTTGAAGCGGTACTTTATAGTAAAAAG
AAAAATGGCAGATCCATGTCATCAGCATTTGTGCTATGGAATGAGTTTCAGAAAATTAAACCCGTTTTATTAAACTCGAT
CTTTCAACGTATAGCCGATATTCCAATATTTATTATATTTCTCATTGTTATATATGTAAATTTAGGTCTGGTCGTTATTG
TCCCTGTTACCATGTTTATCGTCTCTATTATTATTTCCCTCGTTAACCACCATTATACTAATGAGTTAATGAACAAACAA
AAAGAAGGACAGAAGAACAGGAATATCTTCATCTCAGAGGTTTTCTTATCTATTAAAATGATCCATACCTTAAATAATCA
AGGTTTACTTTTTGATTGGGTCAACACATCAAATGAACAGTCGTATCTTAACCTGAAGATAAGGAAATTAAATCTTATCT
ATCAATCTATATTGGGGAGTATGTCATCTATTACCCAAATAACTATTATGGTAATAGCCTTTTTTATGGTAATCAAGGGT
GATGTTACTACTGGCGCAATTGTTTCATCTGTCATTGTCTCTGGTCGTATTTCCGGGATCATTTCGAATTTTTCTTCTAC
ATTAATCTCTATTTTATCAGCAGAAAAAACCGGTAAGGATCTGCTTTCTTTTTTTGATGAAGATCAGGCAGAAAAAACAC
CGGCATTACAGTCCATATCAAAGTGCAATGGCGATATCTCTATTCGGGGTGTGAGTTATCAGTATGACGCTCAATCTCCG
ATGATTATTAACCGACTGTCTATAGACATACCTGCGGGGCAGCGTGTCGCAGTGATAGGCGAATGCGGTGCAGGAAAAAG
CTCATTACTGGGAATGCTATCTGGCTACCTTTCGCCAACAGACGGCGCCATCTTATATGATGGATATAACTTAGGGCATT
TATCGCAGAACTTTTTTTCTCAGCATTTAAGCGTGGTGACGACACATGATGTTTTATTCACCGGAACCATTGAAAGTAAT
TTCGCGTTAAAACCGCAAAACGACAGGGGCCGGGTACTCAAGGCGCTCCATCTGGCGAACTGTGGTTTTATCTTGCAACA
TCCTATGGGGCTGAAGTTTCCGGTGAATTTTATGGCTAAAAACCTGTCATCCGGACAGCAACAGCAGTTATTATTAGCAC
GTAGTCTGAGCAGTAACGCCAGCGTCTTTTTATGGGATGAACCAACATCAAATCTGGATGAAAATACCGAGAAGCAAATT
TTTGATAACTTAGATGAGTTTATTCATGGGAAAACGTTGATCATGGTGACGCATCGTCGATACCTGATAAAGTATTTTGA
CCGGGTCCTGGTAATGAAAGGTGGAAAAATAATCCGTGATTGTTCTCCGGATAAATTATTAACGTAA

Protein sequence :
MDKKLEPYYLSAETALSIVSKKFNIKIDIKEDDINLRFKKYDRNNTDDSIQMKNFFLSLGLSLQDILFNNGEDLLNEPMP
ILLLTPEMKWMVCVSGGQKIKLVNARGELCYVEIEDEYLKELSAFSILPLNKVVDSIRVKNIIKNSLSMNKIFYTKYFFS
SLFMAIFALTIPVFSNLFYDKLVPSASVSSLFGVAIIVAVFIVFEFILRTSKDIYQSITARQDDVDIDIAFLEAVLYSKK
KNGRSMSSAFVLWNEFQKIKPVLLNSIFQRIADIPIFIIFLIVIYVNLGLVVIVPVTMFIVSIIISLVNHHYTNELMNKQ
KEGQKNRNIFISEVFLSIKMIHTLNNQGLLFDWVNTSNEQSYLNLKIRKLNLIYQSILGSMSSITQITIMVIAFFMVIKG
DVTTGAIVSSVIVSGRISGIISNFSSTLISILSAEKTGKDLLSFFDEDQAEKTPALQSISKCNGDISIRGVSYQYDAQSP
MIINRLSIDIPAGQRVAVIGECGAGKSSLLGMLSGYLSPTDGAILYDGYNLGHLSQNFFSQHLSVVTTHDVLFTGTIESN
FALKPQNDRGRVLKALHLANCGFILQHPMGLKFPVNFMAKNLSSGQQQQLLLARSLSSNASVFLWDEPTSNLDENTEKQI
FDNLDEFIHGKTLIMVTHRRYLIKYFDRVLVMKGGKIIRDCSPDKLLT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SC4141 YP_219128.1 bacteriocin/lantibiotic ABC transporter Not tested SPI-4 Protein 0.0 99
siiF CAE11798.1 putative type-I secretion protein (putative inner membrane component) Virulence SPI-4 Protein 0.0 99
STY4460 NP_458560.1 putative type-1 secretion protein Not tested SPI-4 Protein 0.0 99
STM4262 NP_463127.1 ABC-type bacteriocin/lantibiotic exporter Not tested SPI-4 Protein 0.0 99
spi4_R AAC26655.1 ltkB homolog Virulence SPI-4 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN001992_12570 YP_007472252.1 Lipid A export ATP-binding/permease protein msbA VFG0582 Protein 0.0 99