Gene Information

Name : UWK_00709 (UWK_00709)
Accession : YP_007466940.1
Strain : Desulfocapsa sulfexigens DSM 10523
Genome accession: NC_020304
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 820560 - 822296 bp
Length : 1737 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGAGAAAAACAAAAATTATAGCAACGCTGGGGCCTGCTAGTAATACTGTGGAGCAGATTCATGAGCTGATCCTGGCCGG
GGTGGACGTTTTTCGTGTCAATCTTTCTCACGGAGACCACGAGTCTCAGGCAGCCTTCATTGCTGCAATCAAGACAGCTA
GAGCCAGGGCTGGGTGTGAAACCGCTATTCTTCTCGATACCCGGGGGCCTGAAATTCGAACCAGTGATATTGATGAAGGT
TTTATTACGCTTCAGCAGGGACAGACATTCTTTTTGACAATCGATACAGTTGCGGCAACGTCTGAGCGGATTGGCGTGAA
TTATCAGGGCCTTTGCGATGATGTGAACATTGGCGACACCGTTCTTCTCGATGATGGTAAGCTGGCGTTGCGTGTTTTAA
GTCTCCATGGAAATGATATCCGCACCGAGGTTGTCGTTGGTGGTCGTCTGGGAGAGCATAAGCGTGTCAGTCTGCCCGGG
GTCAAGGTCAATTTACCTCCATTGATGGATAAGGATGTTTCGGATATTCAGTTTGGGGCTGAGATGGAGGTGGACTTTAT
CGCAGCCTCCTTTATCCGTAAGGGGGAAGATGTTCTGGAAGTCCGCCGTGTTATAGAAGAAGTTGGAGGCAGGCAGCAGA
TTATTTCCAAGATTGAAAATCAGGAGGCACTCGACAATCTCGAAGAAATTCTTGATTTGTCTGATGGGCTGATGGTGGCC
CGTGGTGATCTCGGAGTGGAACTACCACCGGAGAAGGTCCCGGTTATTCAGAAGAAAATTATCCAGATGGCTAATCGTCA
TGGCAAACCGGTTATCACCGCAACCCAGATGCTGGAATCGATGATTGGCAGTCCCAGGCCCACCAGGGCAGAGGCCAGTG
ATGTGACCAATGCTATTTTTGACGGGACCGATGCAGTGATGTTGTCTGGGGAAACAGCGGTTGGAGGATATCCTCTGGAG
GCTGTTCGTTTCCTGGTTAAAAATGCAGAAATTTCTGAATCTGCCCTTCCCTACGATGAGCTGCTCAGTGCAGGTGCCAG
GTATTCGACCCAAACCGTGTCTAATGCTATCTGCTATGCCGCCTGTGCCATTGCCAGTGACTTGCAGGCACATGCCATCC
TTGCTGCAACTCAGAGTGGCCAGACCGCCCGGATGGTGGCCCGTCATCGTCCCCAGCCGGCCATTATCGCTACAAGCCCG
GAGGCATCAGTGAGGAGGCAGATGCAGTTACTCTGGGGGGTGAGACCTCTGGAAGTTTCCGACGAAGAATCGGTCAATAA
ACTTTTTGACGATGCAATCATTCGTGCCATGGAAAGTGATCTGATGAAATCGGGGGATACCATTGTTATTATTGCTGGCA
TTCCATTTAAAATAAGTGGATCCACCAATATGCTGAAGATCCATGAGGTGGGAGACATTAACCTCCATGGTCAGGGGATT
GGCAAGGAAACAGTTACGGCAGAGGTTACTGTAATAGAAGACACCCACAGTCTTGATGGATTTAAAGTCGGGAATATTCT
TGTTGCCTGCTATACCGATAATTATATGCTGGACAAATTAAGTGGCGCAGCTGGAATTATCACCGAACAACCGGGGCTCA
CATCGCATGCAGCAATTGTTGGCCGGGAAAAAAATATTCCTGTTATTACAGGGGTAAAGGGTGCCATTGAGAAACTGAAA
AGTGGCCAGGTAGTAACTATGAACTGCCATCATGGCCAGATTTACCAGACAAGGTAG

Protein sequence :
MRKTKIIATLGPASNTVEQIHELILAGVDVFRVNLSHGDHESQAAFIAAIKTARARAGCETAILLDTRGPEIRTSDIDEG
FITLQQGQTFFLTIDTVAATSERIGVNYQGLCDDVNIGDTVLLDDGKLALRVLSLHGNDIRTEVVVGGRLGEHKRVSLPG
VKVNLPPLMDKDVSDIQFGAEMEVDFIAASFIRKGEDVLEVRRVIEEVGGRQQIISKIENQEALDNLEEILDLSDGLMVA
RGDLGVELPPEKVPVIQKKIIQMANRHGKPVITATQMLESMIGSPRPTRAEASDVTNAIFDGTDAVMLSGETAVGGYPLE
AVRFLVKNAEISESALPYDELLSAGARYSTQTVSNAICYAACAIASDLQAHAILAATQSGQTARMVARHRPQPAIIATSP
EASVRRQMQLLWGVRPLEVSDEESVNKLFDDAIIRAMESDLMKSGDTIVIIAGIPFKISGSTNMLKIHEVGDINLHGQGI
GKETVTAEVTVIEDTHSLDGFKVGNILVACYTDNYMLDKLSGAAGIITEQPGLTSHAAIVGREKNIPVITGVKGAIEKLK
SGQVVTMNCHHGQIYQTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-80 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-80 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-81 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-81 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UWK_00709 YP_007466940.1 pyruvate kinase VFG0479 Protein 3e-81 45