Gene Information

Name : UWK_00318 (UWK_00318)
Accession : YP_007466556.1
Strain : Desulfocapsa sulfexigens DSM 10523
Genome accession: NC_020304
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 377742 - 379172 bp
Length : 1431 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCACATGTTAGCAAACAATAAAACCAAACTGGTCTGCACCATAGGCCCTGCCTCCGATTCTCCTCGGATGCTCGAAAA
AATGCTTGAAGCCGGGATGAATGTGGCCAGGCTCAATTTTTCCCATGGCGATTTTGCCAGCCATGGCGAAATCATACAAA
GAATCAGGACCGCCTCCGAAAAAACAGGGAAACGAGTTGCCATCCTGGCCGATCTGCCCGGTCCCAAGATGCGCATCCTT
GATCTGGCTGAAGAATTCGTCACCCTTGAAAAAGATGCCTCCTTTATCCTGACTGCAGAAGAAGTTATCGGAACTGCAGA
ACGGGTCGCAATGACCATGAAGGAGCTGCCAGCTGTGGTAAGAAAAGGAGATACCCTTTTTCTTAATGACGGATTGATTG
AATTACGGGTTCAGAAAGTTCAAGGTGAAGATATCCACTGCACCGTAATTGTCGGCGGTAAACTCTGGCCGCGAAAGGGC
CTGAATATCCCGGGAATTGACCTTGGCACCAGTGCCTTCACCGCCCACGACCGCGAGTGCATGCAGTTTGCCCTGGAACA
TGGCGTGGATGCTATTGGTCAGTCCTTTGTAAACACGGCTCAGGATGTACTGGATGTGCGTAAAGCCGCCGCTGAAATGG
GTTTTGATCCCTTTATCGTTTCCAAAATAGAACGGGCCAGCGTCTGGGAAAACATCGATGGAATCCTTGAAGTTACAGAC
GGAGTCATGGTGGCCAGAGGCGACCTTGGTGTGGAAATACCCATTGAAGAGATTGCAGTGGCCCAGAAGACAATCACAGC
CAGGGCCAACCTGTTTGGCATCCCGGTAATCACCGCAACCCAGATGCTCGAATCCATGACCGGGAACCGGAGACCCACCC
GCGCTGAATCCACCGATGTCGCCAATGCGATCCTTGATGGTACCGACTGTGTTATGCTCTCTGAGGAATCTGCCATGGGC
GACTACCCCCTGGAGGCCGTGCAGATGCTTGCCAAAATTGCAAGAGTCACGGAACCACACAGATTGCTGCATAACCACTT
TGAATTCACATTAAAACCACAGGCTACAGGATACACAGCCAGTACCGTTGACATGATAGCTATCTCCATTGAAAATATCT
TTTCCCGGATCGATTCTCTGGCGGCTGTACTTGCCCCAACACATAGTGGCCATATGGCCAGAGCCCTGACTCGTTTTCGT
CTGCCGGTCTGGATTCTGGCAGTATCCACATCGGTCAAGACCTGCCGAGACCTGATGTTCTCCTATGGAGTACATCCAAT
ACTGGAAAAGAAACGACCGGAAAACTGGACTAACACCGCCAGAAACTATATAAAAACATTCGGGTTAGAGGGAAACTGCA
TGGTTAAAGCCGAGGGTCCCTCACCGGACCATCCGGACATTAACCATAAAATGGAAATCATCGAACTGTAA

Protein sequence :
MHMLANNKTKLVCTIGPASDSPRMLEKMLEAGMNVARLNFSHGDFASHGEIIQRIRTASEKTGKRVAILADLPGPKMRIL
DLAEEFVTLEKDASFILTAEEVIGTAERVAMTMKELPAVVRKGDTLFLNDGLIELRVQKVQGEDIHCTVIVGGKLWPRKG
LNIPGIDLGTSAFTAHDRECMQFALEHGVDAIGQSFVNTAQDVLDVRKAAAEMGFDPFIVSKIERASVWENIDGILEVTD
GVMVARGDLGVEIPIEEIAVAQKTITARANLFGIPVITATQMLESMTGNRRPTRAESTDVANAILDGTDCVMLSEESAMG
DYPLEAVQMLAKIARVTEPHRLLHNHFEFTLKPQATGYTASTVDMIAISIENIFSRIDSLAAVLAPTHSGHMARALTRFR
LPVWILAVSTSVKTCRDLMFSYGVHPILEKKRPENWTNTARNYIKTFGLEGNCMVKAEGPSPDHPDINHKMEIIEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-69 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-69 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-69 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-69 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UWK_00318 YP_007466556.1 pyruvate kinase VFG0479 Protein 8e-70 42