Gene Information

Name : UWK_03076 (UWK_03076)
Accession : YP_007469258.1
Strain : Desulfocapsa sulfexigens DSM 10523
Genome accession: NC_020304
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.15
Position : 3419478 - 3420845 bp
Length : 1368 bp
Strand : +
Note : PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI

DNA sequence :
ATGACACTTTTTTCAGGCTCCATTAATGACATTCATCCCATTCGGATATGGGGGAAAGTCACCCGCATAGTAGGTCTTAT
AATTGAGGGACATTGCCCCCACGCCTCTATCGGTTCACTGTGTGAGCTCACCCCCCTAAACAATGGTGCCCCTATTCTTG
CCGAGATCGTCGGTTTTAAAGACTCAAGGGCGCTCCTTATGCCATTAGGAGAACTCCGAGGCCTTGGTCCCGGGAGTAAA
ATACGGGTAATAAAGGAAAGTGCCACCATCAAAGTGGGTCAGAATCTCCTCGGTCGAGTCATTGACGCAATGGAGCAACC
CATTGATGGACAGCCGGCACCACTGCTCGAAGAAGAAAAACTTATTTATTCCCTGCCTCCAGGCCCCATGGAAAGAAAGA
ACATCAGTGAACCGCTGGATCTTGGCATCCGTGCTATCAATGGCCTTATCACCTGTGGTATGGGGCAGCGCATGGGAATT
ATGGCAGGATCGGGTGTGGGAAAAAGTGTACTCCTCGGTATGATGGCAAGATATGCCCGTGCCGATATCAATGTTATAGC
ACTCATTGGGGAAAGGGGCAGAGAGGTACGTGAATTTATCGAAAGAGACCTTGGTAAAGAAGGTTTAGCGCGTTCCGTCA
TAGTTGTAGTAACTTCAGACCAGTCTCCCTTGCTTCGAATGCGAGGGGCCTTTGTAGCCACCTCCATCGCAGAATATTTC
TGCAACAAAGGAAAAAACGTCCTTCTGATGATGGATTCGGTAACCCGTTTTGCCATGGCAATGCGTGAAATCGGCCTCGC
TGTTGGAGAACCGCCTACCACCAAAGGCTACACCCCCTCAGTATTTGCGACCCTTCCAAAGCTTCTTGAACGAGCAGGAC
GCTTTACCGGAAAAGGATCGATCACCGGTCTCTATACAGTTCTTGTTGATGGTGACGATATGACCGAACCTGTAGCCGAT
TCAGTACGCTCTATTCTCGATGGCCACATCGTTCTTTCACGATCCCTTGCTGCCAAAAATCATTACCCGGCCATTGATAT
CATGAACTCGGCCAGTAGAATCATGCGTGAAATCACCCATTCCCGTCATATAGAACTTGCTGGACGTGCCAGAAATGTAC
TGGCTACCTACAATGAAGCAGAAGACCTTATCAACATAGGTGCCTACGCCAAAGGTTCCAACCCGAAAATCGATTTTGCT
GTAAGTAAGATAAACGCAATCAATACCTTTCTCCGTCAGGGCTACGACGAGACAACCCCCCTAAAAGAGACCATTGAATC
CTTGGGTCTGCTCCTGAGCGAGAGGAAAGGTGACACAGACGAACGCCTGGACAGAAGAGAAAGTGATAAACAGAACACTT
CACGATAA

Protein sequence :
MTLFSGSINDIHPIRIWGKVTRIVGLIIEGHCPHASIGSLCELTPLNNGAPILAEIVGFKDSRALLMPLGELRGLGPGSK
IRVIKESATIKVGQNLLGRVIDAMEQPIDGQPAPLLEEEKLIYSLPPGPMERKNISEPLDLGIRAINGLITCGMGQRMGI
MAGSGVGKSVLLGMMARYARADINVIALIGERGREVREFIERDLGKEGLARSVIVVVTSDQSPLLRMRGAFVATSIAEYF
CNKGKNVLLMMDSVTRFAMAMREIGLAVGEPPTTKGYTPSVFATLPKLLERAGRFTGKGSITGLYTVLVDGDDMTEPVAD
SVRSILDGHIVLSRSLAAKNHYPAIDIMNSASRIMREITHSRHIELAGRARNVLATYNEAEDLINIGAYAKGSNPKIDFA
VSKINAINTFLRQGYDETTPLKETIESLGLLLSERKGDTDERLDRRESDKQNTSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-106 55
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-91 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-91 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-92 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-92 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-92 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-91 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-91 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-91 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-91 50
escN AAL57542.1 EscN Virulence LEE Protein 3e-90 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-90 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-90 50
escN AAK26715.1 EscN Virulence LEE Protein 3e-90 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 9e-90 49
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-88 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 9e-90 49
escN AAC38383.1 EscN Virulence LEE Protein 1e-89 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-90 49
escN AAC31513.1 L0034 Virulence LEE Protein 7e-90 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-90 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-90 49
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-90 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-84 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-86 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-86 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-85 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-85 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-86 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-85 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-85 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 8e-71 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-77 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-70 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-73 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-73 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-73 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-70 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-70 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-86 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-79 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-79 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-80 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-73 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 6e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 7e-104 54
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 2e-104 53
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 1e-106 53
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 5e-103 51
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 8e-100 50
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 4e-90 49
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 8e-90 49
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 3e-92 49
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 3e-92 48
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 3e-86 48
UWK_03076 YP_007469258.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 3e-75 43