Gene Information

Name : CONE_0577 (CONE_0577)
Accession : YP_007460298.1
Strain : Candidatus Kinetoplastibacterium oncopeltii TCC290E
Genome accession: NC_020299
Putative virulence/resistance : Unknown
Product : glutamine-hydrolysing GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 368942 - 370528 bp
Length : 1587 bp
Strand : -
Note : Nucleotide transport and metabolism; SecretomeP prediction: 0.22.

DNA sequence :
ATGAATCAACATATTTTAGTAATTGACAATGGCTCACAGGTTACACAACTTATAGCTAGAAGAATAAGAGAAATAGGTGT
TTACACTGAGGTTGAGCCTAATGATATCAGTGAAAAAACTATACAAAAGCATATAAGTAGAGGATTGAAAGGTATTATCC
TATCTGGTAGTTTTGCTTCTGCTTCTGAAGAAAATCTTAAATTAAAATTACCATCATCCATATTCTGTCTAGGTATTCCA
GTACTCGGAATATGTTACGGGATGCAGGCCATGGCAATGGAATTAGGTGGCATGGTTAGTAGTCTGGAAAACAGGGAATT
CGGCTATACAGAAGTAATAAATTGTGAGAATAGTCAATTGCTAGGTAATATCAATGATTTTTCGACAGATAATAAAGAAA
AAATCTTGAGAGTATGGATGAGTCATGCCGACACTGTAACGTCTCTACCCAAAGGTTTTAAAAAAATATCCTATTCCAAA
ATAACATCAGCTATAGCTGGGATGGAGAACGTAGATAGAAAACTATATGCTTTGCAATTTCACCCAGAAGTTACACATAC
TATTCAAGGATACGAAATATTAAAAAGATTTGTAGTTGATATATGCGAATGCAATCTAAAATGGAACATGCCTGATTATG
TGTGTAAGAGCATAGACGAAATAAAATCTTCGATTGGAAAAGATAAAGTAATATTAGGGTTATCTGGAGGTGTGGATTCT
TCAGTAGCGGCTATATTAATACATAAAGCTATAAAAGACCAATTAACATGTATTTTTGTAGATAATGGCTTAATGCGTCT
TGAAGAATTAAATCAAGTAAAAAAAATGTTTTCTGATAAGATGAAAATGAATATTATTTACGTAGACAGTTCAGAAACAT
TTATAAAGAAATTAGCTGGTGTAACTGATCCAGAAATGAAAAGAAAGATTATTGGAAATGAATTTATCAATATATTTCAA
CAAGAGGCCAATAAAATTAAAGATGTATGTTGGCTTGCTCAAGGCACAATATATCCTGATATAATAGAATCATCTCATGG
CAAAAAAGTTATAAAGTCTCATCACAATGTTGGTGGCTTACCAGAAAAAATGAGCCTGAAACTTCTGGAACCTCTTAAAC
ATTTATTTAAAGATGAAGTAAGAAAATTAGGAAAAGAGCTAGGATTAGATGATGAGATGCTTTTTCGTCATCCTTTTCCT
GGTCCTGGACTTGGTGTCAGGATTATAGGAGAAATAAAACCAGAATTTTTAATACTTCTTAAAAAGGCTGATAATATTTT
TATCGAAGAGCTAAAAAATAATATAAATAAAGAAACTAACAAGCAATGGTATTATAGCGTATCACAAGCATTCGCTGTTT
TTTTACCTATTAAATCTGTTGGGGTAATGGGTGATAATCGTACCTATGAGTACGTTATTGCTTTAAGAGCTATAAAAACC
AATGATTTTATGACTGCAGATTGGTTCCACTTGCCGTTTGATTTACTATCAAAAATATCATCAAGAATAATTAATGAAGT
AAAAGGTATTAATAGAGTTGTGTACGATATTTCCAATAAACCTCCAGCAACAGTAGAATGGGAATAG

Protein sequence :
MNQHILVIDNGSQVTQLIARRIREIGVYTEVEPNDISEKTIQKHISRGLKGIILSGSFASASEENLKLKLPSSIFCLGIP
VLGICYGMQAMAMELGGMVSSLENREFGYTEVINCENSQLLGNINDFSTDNKEKILRVWMSHADTVTSLPKGFKKISYSK
ITSAIAGMENVDRKLYALQFHPEVTHTIQGYEILKRFVVDICECNLKWNMPDYVCKSIDEIKSSIGKDKVILGLSGGVDS
SVAAILIHKAIKDQLTCIFVDNGLMRLEELNQVKKMFSDKMKMNIIYVDSSETFIKKLAGVTDPEMKRKIIGNEFINIFQ
QEANKIKDVCWLAQGTIYPDIIESSHGKKVIKSHHNVGGLPEKMSLKLLEPLKHLFKDEVRKLGKELGLDDEMLFRHPFP
GPGLGVRIIGEIKPEFLILLKKADNIFIEELKNNINKETNKQWYYSVSQAFAVFLPIKSVGVMGDNRTYEYVIALRAIKT
NDFMTADWFHLPFDLLSKISSRIINEVKGINRVVYDISNKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-115 48
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-115 48
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-115 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-103 44