Gene Information

Name : CDSE_0599 (CDSE_0599)
Accession : YP_007459332.1
Strain : Candidatus Kinetoplastibacterium desouzaii TCC079E
Genome accession: NC_020294
Putative virulence/resistance : Unknown
Product : glutamine-hydrolysing GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 385198 - 386787 bp
Length : 1590 bp
Strand : -
Note : Nucleotide transport and metabolism; SecretomeP prediction: 0.21.

DNA sequence :
ATGAACCAACATATTTTAATTATCGACTATGGGTCTCAATTTACTCAACTTATTGCACGTAGAATAAGAGAATTAGGAGT
TTATGCAGAAGTAATCCACAATAATATTGATAAAGAATTTATTAACAATAAGATTGATGTTGGATTGAAAGGTATAATTC
TTTCTGGCAGTCATGAGTCAATAGACAATAATGATCATGATACACTTAAGAAATTTATATTAGAAATTGGTATTCCTGTT
TTAGGCATTTGTTATGGAATGCAATTAATGGCAAATCAATTAGGTGGTCAAGTTAGCTTATCAACAAATCGTGAATATGG
AGAAGTAGAACTTATAATCTCAAGCCCTAGTAAACTATTAGATGGAATACAAGTTATTAAAAATAACGATGATGTAAATA
TTCTAAAAGTATTGATGAGTCATGGAGATACTGTTACAAAATTACCTGATGGTTTTAAAAAAATAGCCTATACAAATTCT
TGTCCAATTGCAGGAATGGAAGATAGCAACCGTAATCTTTATGGTTTACAATTTCATCCAGAAGTAACACATACAATATT
AGGAAACAAAATACTCAAAAGGTTTGTAAAAAATATTTGCCAATGTGAATCAAACTGGAGTATGCCAAATTATATAGAAA
ATACAATATCAAGAATAAAATCTGAAGTTGGAGATGATAAAGTAATACTTGGATTGTCAGGTGGAGTTGATTCTTCTGTA
GCTGCCATTCTAATTCATAAAGCTATAGGAGAAAAACTTACATGTGTTTTTGTTGATCATGGATGTATGAGATTAAACGA
AAAAAAACAAGTAGAAAAAATGTTTTCTTCTTACCATATTAATATTATATACAAAGATGCATCTGATTTATTCTTTCAAA
AATTGTCAGGTATAATTGATCCTGAAGAAAAAAGGAAGATAATAGGTGCTGAATTTATTAACGTTTTTCAATCAGAAGCA
AATAAACTTGGTAACATAAAATGGCTAGCTCAGGGTACGATATATCCAGATGTTATAGAATCATCAAATGCTAAAAATGG
ATCTTCTAAGGTTATAAAATCTCATCATAATGTTGGTGGACTTCCAGAAAAAATGAATCTTAAGCTATTAGAGCCATTAA
AATATTTATTTAAAGATGAAGTTAGAAAAATTGGCTTAGAATTAGGAATTTCACCTGAAATGATATTCCGACATCCATTT
CCTGGTCCTGGATTAGCTGTAAGAATAATAGGTGAAGTAAAACCTGAATTTGTAAAAATATTACAAGGTGCTGATAATAT
TTTCATACAAGAATTAAGAAACAATCTTAATCAATTAACTGGTAAAAGTTGGTATGATTCAGTTTCTCAAGCTTTTGCTG
TATTTTTACCTATAAAATCTGTAGGTGTTATGGGAGATCACCGCACTTATGAATATGTTATAGTCTTAAGAGCTGTAAAT
ACTTTAGATTTCATGACAGCAAATTGGTCAAAAATTCCAGATGATTTATTATCAAAAATTTCATCCAGAATTATAAATGA
AATTCCTGGTGTTAATAGAGTTGTATATGATATATCAAATAAACCTCCAGCTACAATAGAGTGGGAATAA

Protein sequence :
MNQHILIIDYGSQFTQLIARRIRELGVYAEVIHNNIDKEFINNKIDVGLKGIILSGSHESIDNNDHDTLKKFILEIGIPV
LGICYGMQLMANQLGGQVSLSTNREYGEVELIISSPSKLLDGIQVIKNNDDVNILKVLMSHGDTVTKLPDGFKKIAYTNS
CPIAGMEDSNRNLYGLQFHPEVTHTILGNKILKRFVKNICQCESNWSMPNYIENTISRIKSEVGDDKVILGLSGGVDSSV
AAILIHKAIGEKLTCVFVDHGCMRLNEKKQVEKMFSSYHINIIYKDASDLFFQKLSGIIDPEEKRKIIGAEFINVFQSEA
NKLGNIKWLAQGTIYPDVIESSNAKNGSSKVIKSHHNVGGLPEKMNLKLLEPLKYLFKDEVRKIGLELGISPEMIFRHPF
PGPGLAVRIIGEVKPEFVKILQGADNIFIQELRNNLNQLTGKSWYDSVSQAFAVFLPIKSVGVMGDHRTYEYVIVLRAVN
TLDFMTANWSKIPDDLLSKISSRIINEIPGVNRVVYDISNKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-118 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-118 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-118 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-107 45