Gene Information

Name : BCUE_0417 (BCUE_0417)
Accession : YP_007449229.1
Strain : Kinetoplastibacterium blastocrithidii TCC012E
Genome accession: NC_020285
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 205947 - 208532 bp
Length : 2586 bp
Strand : +
Note : DNA replication, recombination, and repair; SecretomeP prediction: 0.08

DNA sequence :
ATGAGAACTGATAAATTGACTGTAAAGCTTCAGAAGAATTTATTAGATGCGCAGAGTTTGGCTGTAGTTAATGACAATCA
ATATATTACATCCATACATGTCTTAAAAGCAATGTTGGATGATGATGATGCATTTATTTCTAATATACTGGTTAGCTCTG
GGGTGGCTCTTAACAAATTAAATAGTTTGTTAGATTCTTCTTTAAAGAAATTGCCTCAGGTTCATAATATAGATGATGTT
CAAATAGGTAAAGAACTTCAAGGATTATTTATTAGAGCAGAAAAGGAAGCTAGTAAGAAAGGTGACGACTATATATCTAG
TGAAATATTGTTAATAGTATTAACTGATGATAAAAGCGATGTATCTAGCTTGCTAAAGGAATCTGGTCTAAAAGTTAACT
TATTAAAAGAATCTATTAATAATATTCGTGGTTCTGATAAAATATCTGATGTGAATGATGAATCCAATCGCAATGCATTG
TCTAAGTATACTACTGATGTTACTTCTTTAGCACGTCAGGGCAAACTTGATCCAGTTATAGGTCGTGATGATGAAATAAG
GCGTACTATTCAAATATTACAGCGTCGAACAAAAAATAATCCGGTATTAATTGGTGAGCCAGGTGTTGGTAAGACAGCGA
TAGTGGAAGGTTTAGCTCAGAGGATAATAAATGGAGAAGTGCCTGATAATTTGCGTGATAAGAGAGTACTATCACTAGAT
TTAGCATCTTTAATAGCAGGAGCAAAATTTAGAGGAGAGTTTGAGGAGCGTTTAAAGGCAGTATTAAAGGATATTTCAGC
AGAAAGTAATAGTATACTGTTCATAGATGAATTACATACAATTATGGGAGCAGGTAAGGCAGAGGGATCTATTGATGCTG
GAAACATGCTAAAGCCAGCACTAGCAAGAGGAGAGCTGCACTGTATAGGAGCTACTACTCTTGATGAATATCGCAGATAT
ATAGAGAAGGATGCTGCTTTAGAAAGAAGATTTCAGAAGGTTATTGTAGATGAGCCAAATGTCGAATCTACTATAGCTAT
TCTTCGTGGTTTGCAGGAGCGTTATGAAATTCATCATGGTGTGGAAATTACTGATCCCGCTATAGTTGCAGCAGCAGAGT
TATCTAATCGTTATATTACTGATAGATTTTTGCCAGATAAGGCTATTGACTTAATAGATGAAGCGGGAGCTCGCATTAGA
ATGGAAATTGATTCTAAGCCAGAAGCTATGGATAAGTTAGAGCGTAGAATTATTCAATTAAAGATAGAGCGAGAGGCAGT
AAAAAAAGAATCTGATGAGGTGTCTAAGAAAAGACTGTATTCCATAGAAGATGAATTAAACAAGATACAGAAAGAATATG
ATGATTATGAAAAAATATGGAAATCAGAGAAAAATATTGTAGAGGGCACCAAAAACATAAAAGAAGAGATAGATAGTCTA
AGAGCTAAGATGGCAGAATTACAGAGAAATGGCCAGTACGACCGATTAGCAGAGCTTCAGTATTCAAAATTGCCAGAGTT
AGAAGAAAGATTAAAATCAGCAGAAAGCTATTCCATTAATCAATCAGAGGATAAGAAATTTAAATTACTTCGTACTCAGG
TTGGCGCTGAAGAAATAGCAGAAGTGGTTTCTAGAGCTACAGGTATTCCAGTATCAAAAATGATGCAAGGAGAAAGAGAA
AAATTACTACACATGAGCAATTTTTTAAGCTCTAGAATCATAGGGCAATCTGAGGCAGTTAATGCTGTTTCTGATTCTAT
TCTTCGTGCTAGAGCTGGATTATCAGACCAATCCAGACCTTCTGGATCATTTCTCTTTTTAGGTCCTACAGGGGTAGGGA
AAACAGAGTTAGCGAAGGCTCTTGCTGATTTTATGTTTGATTCTAGAGATCACATGATAAGAATCGATATGAGTGAATTT
ATGGAAAAACATTCAGTTGCGAGACTTATAGGAGCTCCTCCTGGTTATGTTGGTTATGAAGAAGGTGGTTATTTAACAGA
GGCTGTTAGGAGAAAACCTTATAGTGTTGTATTGTTGGATGAAGTTGAAAAAGCTCATTTAGACGTTTTTAATGTTTTAT
TACAAGTTTTAGATGATGGTCGTTTAACGGATAGTCACGGCAGGACTGTTGATTTTAGAAATACAATTATTATAATGACA
TCGAATCTAGGTTCTAATCATATTCAGAACATGATGGATAGTACATATAATGAGATTCGTGATGTTATAATGGAAGAGTT
AAAAGCAACATTAAGGCCTGAATTTCTTAATCGTATAGATGAGATTGTTTTCTTTCATAGTTTAAAGCTAGAGCAAATGA
ATTCTATCGTAAGGATACAAATAGATCAATTGAAAGATCGTTTGAAGCAAAAGAACATATACATAGATATAGCAGAAGAT
GCTATTTTAATGTTGGCAAAGAACGGTTTTGATGTTGTATTTGGAGCTAGACCTCTTAGACGAACAATTCAAAATTATAT
TGAAAATCCTTTGTCTAGATTAATTTTAGAGGGCAAAGTTTCTGATAATGATATTATTAATATAGATTATTCCGATAGTA
AATTTAGATTTAAAATTAATAGTTAG

Protein sequence :
MRTDKLTVKLQKNLLDAQSLAVVNDNQYITSIHVLKAMLDDDDAFISNILVSSGVALNKLNSLLDSSLKKLPQVHNIDDV
QIGKELQGLFIRAEKEASKKGDDYISSEILLIVLTDDKSDVSSLLKESGLKVNLLKESINNIRGSDKISDVNDESNRNAL
SKYTTDVTSLARQGKLDPVIGRDDEIRRTIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPDNLRDKRVLSLD
LASLIAGAKFRGEFEERLKAVLKDISAESNSILFIDELHTIMGAGKAEGSIDAGNMLKPALARGELHCIGATTLDEYRRY
IEKDAALERRFQKVIVDEPNVESTIAILRGLQERYEIHHGVEITDPAIVAAAELSNRYITDRFLPDKAIDLIDEAGARIR
MEIDSKPEAMDKLERRIIQLKIEREAVKKESDEVSKKRLYSIEDELNKIQKEYDDYEKIWKSEKNIVEGTKNIKEEIDSL
RAKMAELQRNGQYDRLAELQYSKLPELEERLKSAESYSINQSEDKKFKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERE
KLLHMSNFLSSRIIGQSEAVNAVSDSILRARAGLSDQSRPSGSFLFLGPTGVGKTELAKALADFMFDSRDHMIRIDMSEF
MEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVVLLDEVEKAHLDVFNVLLQVLDDGRLTDSHGRTVDFRNTIIIMT
SNLGSNHIQNMMDSTYNEIRDVIMEELKATLRPEFLNRIDEIVFFHSLKLEQMNSIVRIQIDQLKDRLKQKNIYIDIAED
AILMLAKNGFDVVFGARPLRRTIQNYIENPLSRLILEGKVSDNDIINIDYSDSKFRFKINS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCUE_0417 YP_007449229.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG0079 Protein 8e-131 45
BCUE_0417 YP_007449229.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2076 Protein 5e-97 43
BCUE_0417 YP_007449229.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 8e-105 42