Gene Information

Name : A284_12287 (A284_12287)
Accession : YP_007443123.1
Strain :
Genome accession: NC_020267
Putative virulence/resistance : Resistance
Product : metallo-beta-lactamase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4519 - 5847 bp
Length : 1329 bp
Strand : +
Note : COG0491 Zn-dependent hydrolases, including glyoxylases

DNA sequence :
ATGTTTTTTAAACAATTTTATGATAAACATTTATCTCAAGCATCTTATTTAATCGGTTGTCAAAAAACTGGAGAAGCCAT
GATTATTGATCCTATTCGTGACTTATCTTCATATATTCGAGTTGCTGATGAAGAAGGTTTAACCATTACTCATGCAGCTG
AAACACATATACATGCAGATTTTGCTTCAGGAATTAGAGATGTTGCTATAAAGTTAAATGCTAATATCTATGTATCAGGT
GAAAGTGATGACACATTAGGTTATAAAAATATGCCTAACCACACTCATTTTGTTCAACATAATGACGATATTTATGTAGG
AAATATAAAATTAAAAGTGCTTCATACACCTGGTCACACGCCAGAAAGTATAAGTTTTTTACTTACTGACGAAGGTGCTG
GAGCACAAGTTTCAATGGGACTATTCAGTGGTGATTTTATTTTTGTAGGAGATATCGGTAGACCTGATTTACTAGAAAAA
GCGGTTAAAGTAGAAGGATCATCTGAAATAGGCGCTAAACAAATGTTTAAATCGATTAAAAGTATTAAAGACTTGCCAGA
CTACATTCAAATTTGGCCTGGCCATGGCGCTGGTAGTCCTTGTGGTAAATCTTTAGGTGCTATTCCAACATCTACGCTTG
GCTATGAAAAACAAACGAACTGGGCTTTTTTTGAAAATAACGAAGCTACCTTTATCGATAAACTCATTTCTGATCAACCT
GCACCACCACATCATTTTGCACAAATGAAAAAAATTAATCAATTCGGTATGAATTTATATCAACCTTATACGGTTTATCC
AACTACAAATACAAACAGATTAACTTTTGATCTCCGCAGTAAGGAGGCTTATCATGGTGGACATATTGAAGGTACAATCA
ATATTCCATATGATAAAAATTTCATCAATCAAATTGGCTGGTATCTAAACTATGATCAAGAAATTAACTTGATTGGAGAC
TATCACCTTATTTCAAAAGCAACACACACCTTACAACTCATTGGATACGATGATGTTGCTGGATATCAATTACCTCAATC
TAAGATTCAAACACGTTCCATTCATAGTGAAGACATTACAGGTAACGAATCACATATATTAGATGTACGTAATGATAATG
AATGGAATAATGGCCACTTATCTCAAGCGGTTCATGTACCACACAGCAAACTTTTAGAAACAGATTTACCTTTCAATAAA
AACGATGTTATTTATGTACACTGTCAGTCTGGCATTAGAAGTTCGATAGCTATTGGTATTTTAGAACATAAAGGTTATCA
CAACATTATTAATGTAAATGAAGGTTACAAAGATATACACCTTTCTTAA

Protein sequence :
MFFKQFYDKHLSQASYLIGCQKTGEAMIIDPIRDLSSYIRVADEEGLTITHAAETHIHADFASGIRDVAIKLNANIYVSG
ESDDTLGYKNMPNHTHFVQHNDDIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVSMGLFSGDFIFVGDIGRPDLLEK
AVKVEGSSEIGAKQMFKSIKSIKDLPDYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFFENNEATFIDKLISDQP
APPHHFAQMKKINQFGMNLYQPYTVYPTTNTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYDQEINLIGD
YHLISKATHTLQLIGYDDVAGYQLPQSKIQTRSIHSEDITGNESHILDVRNDNEWNNGHLSQAVHVPHSKLLETDLPFNK
NDVIYVHCQSGIRSSIAIGILEHKGYHNIINVNEGYKDIHLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 0.0 99
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 0.0 99
unnamed BAB83478.1 - Not tested SCC 12263 Protein 0.0 96
SAV0046 NP_370570.1 hypothetical protein Not tested Type-II SCCmec Protein 6e-122 75
SA0043 NP_373283.1 hypothetical protein Not tested Type-II SCCmec Protein 6e-122 75
unnamed BAC57482.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 5e-122 75