Gene Information

Name : guaA (CSSP291_03705)
Accession : YP_007439628.1
Strain : Cronobacter sakazakii Sp291
Genome accession: NC_020260
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 779271 - 780848 bp
Length : 1578 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACGGACAACATTCATAAGCATCGTATCCTTATCCTCGACTTCGGTTCTCAGTACACCCAACTGGTGGCGCGCCGCGT
GCGTGAGCTGGGCGTTTACTGTGAACTGTGGGCCTGGGACGTGACGGAAGAGCAAATCCGCGGCTTTAATCCTAACGGGA
TTATCCTTTCCGGTGGCCCGGAGAGCACCACTGAAGAAAACAGCCCGCGCGCGCCGGAATATGTCTTTAACGCCGGTGTG
CCGGTGCTTGGCGTTTGCTACGGTATGCAGACCATGGCGATGCAGCTGGGCGGCCATGTGGAAGGTTCTAACGAGCGTGA
ATTCGGTTATGCGCAGGTAGAAGTTAAAACCGACAGCGCGCTGGTGCGTGGTATTGAAGATGCGCTGAGCGCCGACGGCA
ACCCGCTGCTGGATGTCTGGATGAGCCACGGCGATAAAGTGACCGCTATTCCGTCTGATTTCGTGACCGTCGCCAGCACC
GAAACCTGTCCGTTCGCGATCATGGCGAACGAAGAGAAGCGTTTCTACGGCGTGCAGTTCCACCCGGAAGTGACTCACAC
CCGTCAGGGCCTGCGTATGCTGGAGCGCTTTGTGCGCGACATCTGTGAGTGCGAAGCGCTGTGGACGCCGGCGAAAATCA
TCGACGACGCGGTTGAGCGCATTCGTCAGCAGGTGGGTAACGATCGCGTGATCCTGGGCCTCTCCGGCGGCGTGGACTCC
TCCGTCACCGCCATGCTGCTGCACCGCGCGATTGGCGACCGTCTGACCTGCGTGTTCGTTGATAACGGCCTGCTGCGCCT
GAACGAAGCCGAGCAGGTGATGGATATGTTCGGCGACCATTTTGGTCTTAACATCGTTCACGTCCCGGCGGAAGCGCGCT
TCCTCGACGCGCTGGCGGGCATCGACGAGCCGGAAGCCAAACGTAAAACCATTGGTCGCGTATTCGTGGAAGTGTTCGAT
GAAGAAGCGCTGAAGCTGGAAGATGTGAAATGGCTGGCGCAGGGCACTATCTACCCGGATGTGATTGAATCTGCGGCGTC
TGCCACCGGCAAAGCGCACGTGATCAAATCTCACCACAACGTGGGCGGCCTGCCGAAAGAGATGAAAATGGGCCTCGTCG
AGCCGCTCAAAGAGCTGTTTAAAGACGAAGTGCGCAAAATTGGTCTGGAGTTGGGCCTGCCGTATGACATGCTCTATCGC
CACCCGTTCCCGGGGCCGGGTCTCGGTGTGCGCGTGCTGGGCGAAGTGAAAAAAGAGTACTGCGACCTGCTGCGCCGCGC
CGACGCTATCTTTATCGAAGAGCTGCGCCGTGCGGATCTGTACGACAAAGTGAGCCAGGCATTCGCGGTGTTCCTGCCGG
TGCGCTCTGTCGGCGTCATGGGAGATGGCCGTAAGTATGACTGGGTCGTCTCACTGCGTGCGGTCGAAACCATCGACTTT
ATGACCGCTCACTGGGCGCATCTGCCATACGATTTCCTGGGCCGCGTTTCCAACCGTATTATCAATGAAATCAACGGCAT
TTCCCGTGTGGTTTATGATATCAGCGGTAAACCGCCCGCGACGATTGAGTGGGAATGA

Protein sequence :
MTDNIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEEQIRGFNPNGIILSGGPESTTEENSPRAPEYVFNAGV
PVLGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVKTDSALVRGIEDALSADGNPLLDVWMSHGDKVTAIPSDFVTVAST
ETCPFAIMANEEKRFYGVQFHPEVTHTRQGLRMLERFVRDICECEALWTPAKIIDDAVERIRQQVGNDRVILGLSGGVDS
SVTAMLLHRAIGDRLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEARFLDALAGIDEPEAKRKTIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRRADLYDKVSQAFAVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEINGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-129 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-130 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-130 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-111 48