Gene Information

Name : CSSP291_10255 (CSSP291_10255)
Accession : YP_007440925.1
Strain : Cronobacter sakazakii Sp291
Genome accession: NC_020260
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2135860 - 2137806 bp
Length : 1947 bp
Strand : -
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAGCCCAGTCTGGGGCGCGCCATCGCCGACGTGTTGCCGAAACCGCACCGCCGGGGCGA
CGGGTTTATTGAGTGCGGGAACGGCCAGGTGGTCACCTGGTGCGTCGGGCATCTGCTGGAGCAGGCGCAGCCGGACGCCT
ATGACAGCCGCTATGGCCGCTGGAATCTCGCCGACTTACCCATCGTGCCGGAAAAGTGGCAACTCCAGCCGAAACCGTCG
GTTGCAAAGCAGCTTAATGTGATTAAAAAGCTGCTGCGCGAGGCGCAGGAGATTGTTCACGCAGGCGACCCGGACCGCGA
AGGGCAACTGCTGGTGGATGAAGTGCTCGACTACCTGCAACTGCCCGCGGAAAAGCGCCAGCAGGTGCGCCGCTGCCTGA
TTAACGATCTCAACCCGCAGGCGGTGGAGCGTGCTATCGATAAACTGCGCGAGAACCGCGAGTTTGTGCCGCTCAGCACC
TCGGCGCTCGCCCGCGCCCGCGCGGACTGGCTTTACGGCATTAACATGACGCGCGCTTATACGCTGCTCGGGCAGAACGC
GGGCTACCAGGGCGTGCTCTCGGTAGGCCGCGTCCAGACGCCCGTGCTGGGGCTGGTGGTGCGGCGCGACGAAGAGATTG
AAAACTTTGTCGCCAAAGATTTCTTTGAGGTCAAAGCGCACATCGTCACGCCCGCGCAGGAGCGCTTTACTGCGCTCTGG
CAGCCGAGCGAGGCCTGCGAGCCGTACCAGGATGAAGAGGGGCGGCTCCTCAACCGCGCGCTGGCGGAGCATGTCGTTAA
GCGTATTGAAGGGCAGCCTGCGGTTGTCACCAGCTATAACGACAAGCGCGAAAGCGAGGCCGCGCCGCTGCCGTTCTCCC
TCTCGACGCTGCAAATCGAGGCCGCCAGACGCTTCAACCTGAGCGCGCAGACGGTGCTGGATATCTGCCAGAAGCTATAC
GAAACCCACAAACTCATTACGTACCCGCGCTCCGACTGCCGCTACCTGCCGGAAGAACATTTCGCGGGCCGCCATGCGGT
GCTGAAGGCGATTGGCGTTCACGCGCCGGATCTCCTGCCGCAGCCCGCAGTCGATCCTGAGCGCCGCAACCGCTGCTGGG
ATGACAAAAAAGTGGACGCGCACCACGCCATTATCCCGACCGCCCGCAGCGCGCCCGCGTCGCTCTCTGACGGCGAGGCG
AAAATCTACGGGCTTATTGCCCGTCAGTACCTGATGCAATTCTGCCAGGACGCGCAGTTCCGCAAATGCGTGATTGAACT
TGAAATCGCGGGCGGCAAATTCATCGCCAAAGCGCGCTTTCTGGCGGAAACGGGCTGGCGCGCGCTGCTTGGCGCCAAAG
AGCGCGACGAAGAGAACGACGGCACGCCGCTGCCGGTGGTGGCAAAGGGCGACGAGCTGCACTGCGAGCATGGCGAAGTG
GTCGAACGCCAGACCCAGCCGCCGCGCCACTTTACCGATGCCACGCTGCTCTCCGCCATGACCGGCATCGCGCGTTTCGT
GCAGGATAAAGATCTGAAGAAGATCCTGCGCGCCACCGACGGACTTGGCACCGAAGCGACCCGCGCAGGCATTATCGAGC
TTTTATTTAAGCGCGGTTTTCTTGAAAAGCAGGGGCGCTATATTCATTCGACGCCCGCCGGGAAAGCGCTGATCCACGCG
CTGCCGGAGCTTGCCGCACGCCCGGACATGACCGCGCAGTGGGAATCGACGCTGACGCAAATCAGCGAGAAGCAGTGCCG
CTATCAGGATTTCATGCAGCCGCTGGTGCAGACGCTCTACACGCTGATTGACCAGGCGCGCAGCGCCCCGGTGCGCCAGT
TCCGCGGTCTGGTGGCGCCCCAGCAGGCGCAAAAACGCCGCGCGGGCAAAGGCGGCAAAAAGCCGGCGTCCCGCAAGCGC
GGCAGCGCCCAGCCTGCGGCGGAGTAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRRGDGFIECGNGQVVTWCVGHLLEQAQPDAYDSRYGRWNLADLPIVPEKWQLQPKPS
VAKQLNVIKKLLREAQEIVHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDKLRENREFVPLST
SALARARADWLYGINMTRAYTLLGQNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPAQERFTALW
QPSEACEPYQDEEGRLLNRALAEHVVKRIEGQPAVVTSYNDKRESEAAPLPFSLSTLQIEAARRFNLSAQTVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRHAVLKAIGVHAPDLLPQPAVDPERRNRCWDDKKVDAHHAIIPTARSAPASLSDGEA
KIYGLIARQYLMQFCQDAQFRKCVIELEIAGGKFIAKARFLAETGWRALLGAKERDEENDGTPLPVVAKGDELHCEHGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLEKQGRYIHSTPAGKALIHA
LPELAARPDMTAQWESTLTQISEKQCRYQDFMQPLVQTLYTLIDQARSAPVRQFRGLVAPQQAQKRRAGKGGKKPASRKR
GSAQPAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-109 41
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-109 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-109 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 7e-102 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 7e-104 41
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 3e-103 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-112 41