Gene Information

Name : merA (CU7111_0621)
Accession : YP_007416459.1
Strain : Corynebacterium urealyticum DSM 7111
Genome accession: NC_020230
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 742069 - 743490 bp
Length : 1422 bp
Strand : -
Note : -

DNA sequence :
ATGCCTACGAAGTACGATCTCGCCATCATCGGATCGGGAGGCGGCGCGTTCGCCGCTGCGATCCGCGCCAGCACGCTCGG
GAAGTCGGTGGTGATGATCGAGCGCGGGACGCTCGGCGGCACCTGCGTGAACACGGGCTGCGTCCCGTCGAAGACGCTCA
TTGCCGCGGCCGGCGCGCGGCACGTCGCGGTCGACGCCGCAACCCGGTTCCCCGGGATCGCGACGACGGCGGATCCCGTC
GACATGCCCGCGCTGATCGCCGGGAAGCAAGCGTTGGTGGAGTCGCTGCGCGGCGAGAAGTACGCCGACGTCGCCGACTC
CTACGGCTGGCAGGTCCTCCGCGGCGACGCCTCGTTCGTGGGCACCCCTGATGCGCCGGTTCTCGATGTTGCCGGATCCG
ACGGAAGCGTCGAGACCATCGAGGCCCACCACTACCTGGTCGCGACTGGTTCTCGCCCGTGGGCACCGCCGATCGACGGC
CTGGAGGAGACCGGATACCTGACCTCGACCACGGCGATGGAGCTGACGGAGGTCCCCGAGTCGCTGCTGGTGCTCGGCGG
CGGCTACGTCGCCCTGGAGCAGGCGCAGCTGTTCGCCCGCCTCGGCTCGCAGGTCACGCTGCTCGTGCGGTCCCGGCTCG
CGTCGAAGGAGGAGCCGGAGGTGTCGAAGGCGCTCCAGGAGGTGTTCGCCGACGAGGGTATCCGCGTCGTCAGCCGCGCA
GTGCCCACCCGGGTCTCCCGCGGCACGGGAGGCGAGGCCGTCGTGACCGCCGCCTTGTCCGGCGGCTCGCAGGAGTTCCG
CGCCGACCAGGTCCTGGTCGCCCTCGGACGCCGTCCCGTCACCGATGGCCTGAACCTCGATGCGGTCGGGGTGAATACCG
GAGACTCCGGCGAGGTGGTCATCTCCGACCGGTTGCAGTCCTCGAACCCGCGGGTCTGGGCCGCGGGCGACGTGACCGGG
CACCCCGAGTTCGTCTACGTCGCCGCCCACCACGGCACCCTCGTCGCCGAGAACGCGTTCGCCGACGCCGACCGGTCCGT
CGACTACGCCCGCCTGCCGCGGGTGACGTTCACCGGGCCCGCGATCGGCGCGGTCGGGATGACCGAGAAGGACGTCCTCG
CCGCGGGGATCCGCTGCGACTGCCGCGTCCTGCCCCTGCACCACGTGCCCCGCGCCTTGGTGAACCGCGACACCCGCGGG
TTCATCAAGATCGTCGTGAACGCCGAGACGAACGAGATCCTCGGCCTGACCGCCGTCGCCAAGGACGCCGGGGAGCTCGC
CGCCGCAGGCGTCCACGTGCTCGGCAGGACCGTCGCCGAGGTCGCCAACGCCTGGGCCCCCTACCTGACCATGGCCGAGG
GCATCCGGATCGCCGCGAAGGCCTTCACCACCGACCCGTCGCTGCTGTCGTGCTGCGCATGA

Protein sequence :
MPTKYDLAIIGSGGGAFAAAIRASTLGKSVVMIERGTLGGTCVNTGCVPSKTLIAAAGARHVAVDAATRFPGIATTADPV
DMPALIAGKQALVESLRGEKYADVADSYGWQVLRGDASFVGTPDAPVLDVAGSDGSVETIEAHHYLVATGSRPWAPPIDG
LEETGYLTSTTAMELTEVPESLLVLGGGYVALEQAQLFARLGSQVTLLVRSRLASKEEPEVSKALQEVFADEGIRVVSRA
VPTRVSRGTGGEAVVTAALSGGSQEFRADQVLVALGRRPVTDGLNLDAVGVNTGDSGEVVISDRLQSSNPRVWAAGDVTG
HPEFVYVAAHHGTLVAENAFADADRSVDYARLPRVTFTGPAIGAVGMTEKDVLAAGIRCDCRVLPLHHVPRALVNRDTRG
FIKIVVNAETNEILGLTAVAKDAGELAAAGVHVLGRTVAEVANAWAPYLTMAEGIRIAAKAFTTDPSLLSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-87 45
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-87 45
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 4e-71 45
merA ABQ57371.1 MerA Not tested SGI1 Protein 3e-70 44
merA AGK07021.1 MerA Not tested SGI1 Protein 3e-70 44
merA AGK07079.1 MerA Not tested SGI1 Protein 3e-70 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-68 44
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-67 44
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-67 44
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-67 44
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-68 44
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-67 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_007416459.1 putative mercuric reductase BAC0651 Protein 1e-87 45
merA YP_007416459.1 putative mercuric reductase BAC0224 Protein 1e-85 45
merA YP_007416459.1 putative mercuric reductase BAC0652 Protein 9e-70 44
merA YP_007416459.1 putative mercuric reductase BAC0653 Protein 4e-67 42