Gene Information

Name : entE (SMWW4_v1c03160)
Accession : YP_007404142.1
Strain : Serratia marcescens WW4
Genome accession: NC_020211
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 371919 - 373553 bp
Length : 1635 bp
Strand : +
Note : -

DNA sequence : 
ATGAGCATTGCCTTTACCCCCTGGCCGGCGGAGTTCGCCAGCCGCTATCGCGAGCGCGGCTACTGGATTGACAAACCGCT
GACCGAGATCCTCGACCGCCAGGCCAACAACGACGCCCCGGCGATCATCGACGCCCAGGGCAGCCTGACCTACCGCGAGC
TGCAGCAGCGCTCCGATCGCCTGGCAGCCGCTTTGCTGCGCCGCGGCGTGAAATCCGGCGACACCGCACTGGTGCAGCTG
GGCAACGTGGCGGAGTTCTATATCGTGTTCTTCGCGCTGCTGAAAATTGGTGTGGCGCCGGTCAACGCGCTGTTCAGCCA
TCAGCGCAGTGAGCTGAACGCCTATGCCGAGCAGATCAAACCGGCGCTGCTGATCGCCGATCGCCAGCACGCGCTGTTTG
CCGACGATCAATTCCTGAACGCCTTCCGCGATGCGCATCCTTCGCTGCGCGTCGTGGCGCTGCGCAGTCAGGCCGAGGGC
GAGCTGGCGCTGGCCGCCTGGCTGAACGAAGCGAGCGACGGTTTCGTCGCGCAGCCTTCCGCGGCCGATCAGGTGGCGTT
CTTCCAGCTTTCCGGCGGCAGCACCGGTACGCCGAAGCTGATCCCGCGCACCCACAATGATTACTACTACAGCATTCGCC
GCAGCGTGGAGATCTGCCGCTTCGACGCGCAGACCCGCTATCTGTGCGCGCTGCCGGTGGCGCACAACTACCCGATGAGT
TCGCCGGGCGTGCTGGGCGTGTTTTATGGCGCCGGGCTGGTGGTGTTCGCCGCCGATCCGGACGCCGGGCAATGCTTCCG
CCTGATCGAACAGCACCAAATCAACGTGACGGCGCTGGTGCCGCCGGCGGTCACGCTGTGGCTGCAGGCGATCGAAGAGT
GGGGCGGCAATGCCCAGCTCGCCAGCCTGAAACTGCTGCAGGTGGGCGGCGCCAAGCTGGGCGAAACGCTGGCGGCGCGC
ATTCAGAACGAAATCGGCTGCCAACTGCAGCAGGTGTTCGGCATGGCGGAAGGGCTGGTGAACTACACCCGGCTGGACGA
TGACGAACGCCACATTCTGGCGACGCAAGGGCGGCCGATGTCGCCGGACGACGAAGTGTGGGTGGCGGATGACGACGGCA
ATCCGTTGCCGGCGGGCGAGGTCGGGCGGTTGATGACGCGCGGGCCTTACACCTTCCGCGGTTACTACCAGAGCCCGGCG
CACAACGCCGATGCTTTCGACGCCGACGGTTTCTACTGCTCCGGCGATCTGATCAGCATCAGCGAAGACGGTTACATCAC
CGTGCAGGGGCGGCAAAAAGACCAGATCAACCGCGGTGGGGAGAAGATCGCCGCCGAGGAGATCGAGAACCTGCTGCTGC
GTCATCCTGACGTGATCAACGCCGCGCTGGTGTCGATGCCGGACGCGCTGATGGGGGAGAAGAGCTGCGCCTATATCATC
GCCAACGCGCCGCTGAAACCGGTGGTGCTGCGCCGTCACCTGCGTGAACAGGGCGTGGCGGACTTCAAACTGCCGGATCG
CTTTATTCAGGTGGACAGCCTGCCGCTGACCCCGGTCGGCAAAGTGGACAAAAAACGGCTGCGCCAGCAGCTCGACGCGC
AACTACAGACTCAGGCTCAGGCTCAGGGAGATTAA

Protein sequence : 
MSIAFTPWPAEFASRYRERGYWIDKPLTEILDRQANNDAPAIIDAQGSLTYRELQQRSDRLAAALLRRGVKSGDTALVQL
GNVAEFYIVFFALLKIGVAPVNALFSHQRSELNAYAEQIKPALLIADRQHALFADDQFLNAFRDAHPSLRVVALRSQAEG
ELALAAWLNEASDGFVAQPSAADQVAFFQLSGGSTGTPKLIPRTHNDYYYSIRRSVEICRFDAQTRYLCALPVAHNYPMS
SPGVLGVFYGAGLVVFAADPDAGQCFRLIEQHQINVTALVPPAVTLWLQAIEEWGGNAQLASLKLLQVGGAKLGETLAAR
IQNEIGCQLQQVFGMAEGLVNYTRLDDDERHILATQGRPMSPDDEVWVADDDGNPLPAGEVGRLMTRGPYTFRGYYQSPA
HNADAFDADGFYCSGDLISISEDGYITVQGRQKDQINRGGEKIAAEEIENLLLRHPDVINAALVSMPDALMGEKSCAYII
ANAPLKPVVLRRHLREQGVADFKLPDRFIQVDSLPLTPVGKVDKKRLRQQLDAQLQTQAQAQGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-90 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-90 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 44
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-90 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-90 44
ybtE CAA21394.1 - Virulence HPI Protein 2e-90 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-91 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-91 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_007404142.1 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex VFG0932 Protein 0.0 74
entE YP_007404142.1 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex VFG0168 Protein 2e-110 47
entE YP_007404142.1 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex VFG1817 Protein 3e-91 42