Gene Information

Name : cadA1 (GHH_c07000)
Accession : YP_007400991.1
Strain : Geobacillus sp. GHH01
Genome accession: NC_020210
Putative virulence/resistance : Resistance
Product : putative cadmium-transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 682818 - 684944 bp
Length : 2127 bp
Strand : +
Note : -

DNA sequence :
GTGGGGAATGAACAAACATTGGATCGGCTTGAGGCCAAAACATACCGCGTGCAAGGACTGACGTGCACAAACTGCGCAGC
TAAGTTTGAGCAAAACGTGAAATCCTTGCCCGGCGTGAAAGAGGCGAAAGTGAATTTCGGCGCCGCCAAGCTCACCGTTT
GGGGCGAGGCGACGATTGATGAACTTGAGCAGGCAGGAGCGTTTGAACAGTTGACCATTCGTGAAGAACGAGAGCGCACG
GTTCAGCGAGAGCCGTTTTGGAAGCGAAAAGAAAATCGAAATGTCTTCGCCTCTGTGGCACTGCTTCTGTTTGGCGTTGC
GGCGGATGCGGCAGACAAGGGGATGCTGGCGATTGCGATGTATTTGGCGGCGATCGTGATCGGCGGCTACTCCCTGTTCT
GGACGGGGCTCCGGAATCTGGCCCGCTGGCAGTTTGATATGAAAACGTTAATGACGATCGCCATTCTTGGCGCGGCGGCC
ATTGGCGAATGGCAGGAAGGGGCGGTCGTTGTCATTTTGTTTGCCATTAGCGAAGCGCTCGAGCGCTATTCGATGGATCG
GGCGCGGCGGTCGATTGCCTCCTTGATGGAGATGGCGCCGGCGGAGGCGACGATCCGGCGCGGCGCCGAGGAAATGACCG
TTCCGGTCGAAGACGTTCGCGTCGGGGATGTCATGATCGTCAAGCCGGGTGGAAAAATCGCTTTGGACGGCATTGTCATA
AGCGGCGCCTCGACAGTGAATGAAGCGGCGATCACCGGCGAAAGTCTGCCGGTGGAAAAAACAGTGGGAGACGCAGTGTT
TGCCGGGACGCTGAATGGAGAAGGATTCCTCGAAGTTGAAGTGACAAAACGGGCGGACGAGACGACATTGGCGAAAATGA
TTGATCTTGTGGAAGAGGCGCAAGCGGAGCGGGCTCCGATGCAAGCGTTTGTCGACCGGTTTGCCCGCTATTATACGCCG
TTTGTGATCGTGACCGCGCTTCTGATCGCTCTTGTGCCGCCGCTCGTGATGGGTGGGGAGTGGCTTGATTGGATTTACCG
CGGTCTTGCCGTTCTTGTCATCGGCTGCCCGTGCGCGCTCGTCATCTCAACGCCGGTGGCGATTGTGACGGCCATCGGCA
ACGCGGCCCGGCGCGGCGTGCTCATCAAAGGCGGGGTATATCTCGAACAAATCGGACGGCTGCGGGCGGTGGCCTTGGAT
AAAACGGGGACGTTGACGGAAGGGAAACCAGCCGTGACCAATGTCGTCGTATATGAAGGGACACGTGAACAGCTGTTGGC
TATCGCCGCCGCCATCGAAAAACGATCGCAGCACCCTTTGGCTTCGGCCATCATCCGCAAAGCGGAAGAGGAAGGAGCGC
CGTTTCTTGACGCGTCAGTTGATGCGTTTCAGTCGTTGACCGGAAAAGGAGTCAAGGCCGCTGTCGGAAACGAAACGTAT
TATATCGGCAGCCCGGCCTTGTTCACCAGTTTGATCGGGAAGTTGCCCGATGAAGCGGAAAAGCAAATCTCTGCCTTCCG
AGACGAAGGAAAAACCGTGATGGCCGTCGGCACGACCGATCGGCTGTTGGGTCTTATCGCCGCGGCCGATCAACTGCGGC
CGTCCGCACCGGAAACGGTCGCCGCGCTGCGGCGCCTTGGAGTGGCGGAAGTGGTGATGGTGACGGGCGACCACGAGCAA
ACCGCACAGGCCATTGGCCGCCAAGCGGGCGTATCCGATATTCGCGCCGGGCTGCTTCCGGAACAGAAGCTTTCGGCGAT
CCGCGAGTTGAAACAGCGCTGCGGCATAACCGCCATGGTCGGTGACGGGGTGAATGACGCCCCTGCCTTGGCCGCGGCCG
ATATTGGTGTGGCGATGGGCGGGGCGGGGACGGATGCCGCCTTGGAAACAGCCGATGTTGTGCTCATGGCCGATGATTTG
CGCCAGCTTCCGTACACGATCCGCCTTGGGCGCCGAACGCTGGCCGTCATCCGGCAAAACATCGCCGTCGCCTTAGGGCT
TAAAGTGCTGGCACTCGTGGCTGCCGTCCCGGGCTGGCTCACCCTTTGGCTTGCGGTGTTCGCCGACATGGGCGCGACGC
TGCTCGTGACATTCAACAGCATGCGCCTGCTGCGGGTGAAGGAATGA

Protein sequence :
MGNEQTLDRLEAKTYRVQGLTCTNCAAKFEQNVKSLPGVKEAKVNFGAAKLTVWGEATIDELEQAGAFEQLTIREERERT
VQREPFWKRKENRNVFASVALLLFGVAADAADKGMLAIAMYLAAIVIGGYSLFWTGLRNLARWQFDMKTLMTIAILGAAA
IGEWQEGAVVVILFAISEALERYSMDRARRSIASLMEMAPAEATIRRGAEEMTVPVEDVRVGDVMIVKPGGKIALDGIVI
SGASTVNEAAITGESLPVEKTVGDAVFAGTLNGEGFLEVEVTKRADETTLAKMIDLVEEAQAERAPMQAFVDRFARYYTP
FVIVTALLIALVPPLVMGGEWLDWIYRGLAVLVIGCPCALVISTPVAIVTAIGNAARRGVLIKGGVYLEQIGRLRAVALD
KTGTLTEGKPAVTNVVVYEGTREQLLAIAAAIEKRSQHPLASAIIRKAEEEGAPFLDASVDAFQSLTGKGVKAAVGNETY
YIGSPALFTSLIGKLPDEAEKQISAFRDEGKTVMAVGTTDRLLGLIAAADQLRPSAPETVAALRRLGVAEVVMVTGDHEQ
TAQAIGRQAGVSDIRAGLLPEQKLSAIRELKQRCGITAMVGDGVNDAPALAAADIGVAMGGAGTDAALETADVVLMADDL
RQLPYTIRLGRRTLAVIRQNIAVALGLKVLALVAAVPGWLTLWLAVFADMGATLLVTFNSMRLLRVKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 56
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 55
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA1 YP_007400991.1 putative cadmium-transporting ATPase BAC0298 Protein 7e-116 51
cadA1 YP_007400991.1 putative cadmium-transporting ATPase BAC0124 Protein 5e-100 44
cadA1 YP_007400991.1 putative cadmium-transporting ATPase BAC0092 Protein 3e-108 43
cadA1 YP_007400991.1 putative cadmium-transporting ATPase BAC0461 Protein 3e-98 42