Gene Information

Name : cadA2 (GHH_c17360)
Accession : YP_007402014.1
Strain : Geobacillus sp. GHH01
Genome accession: NC_020210
Putative virulence/resistance : Resistance
Product : putative cadmium-transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.1.-
Position : 1732186 - 1734324 bp
Length : 2139 bp
Strand : +
Note : -

DNA sequence :
GTGTCTGAACAACAAGCAAAATTATCTAAATCAGAAGCGAAAACCTACCGTGTTCAAGGATTTACTTGTGCAAACTGTGC
GGCAAAGTTTGAAAATAACGTAAAAGCATTGCCAGGTGTTCAAGATGCTAAAGTAAACTTTGGAGCATCTAAAATTACCG
TTTGGGGTACAACAACCATCGAAGAATTAGAAAAAGCAGGAGCTTTTGAAAACTTAAAGGTTCGGGAAGATAAAGAAAAA
TCAGTCAAGCGTGAACCTTTTTGGAAGCAAAAAGAGAACATTAGAGTGTATATTTCCGCCGTTTTGCTTGTGATTAGTTG
GTTTTTAGGGAAGCAATACGGAGAAGAGCATATCTTTGCGACAATTGGATATGCTGCAGCAATTTTAATCGGTGGATATT
CGTTATTTATAAAAGGTTTCAAAAACCTAGTTCGATTGAATTTTGATATGAATACGCTGATGACAGTGGCGATTTTAGGA
GCTGCAGCGATTGGTGAATGGGGAGAAGGTGCAACGGTTGTTATTCTATTCGCCATTAGCGAAGCCTTAGAGCGTTATTC
CATGGATAAAGCTCGTCAATCCATTGAATCGTTGATGGATATTGCTCCAAAAGAAGCATTAATTCGTCGCGGAAATGAAG
AAATGATGGTCCCTGTTGACGATATTCAAGTCGGAGATATTATGATCGTAAAGCCTGGTCAGAAATTAGCGATGGATGGA
ATCGTCATCAAGGGTACATCTACATTAAATCAGGCTGCCATTACGGGAGAAAGTGTTCCAGTAACCAAAACAGTCGGTGA
TGAAGTCTTTGCAGGAACATTGAATGAAGAAGGGTTATTGGAAGTAAAAGTGACAAAACGAGTGGAAGATACAACTCTTT
CGAAAATCATCCATTTAGTGGAAGAAGCTCAAGCAGAACGAGCGCCTTCTCAAGCGTTTGTAGATCGTTTTGCCAAATAC
TATACACCAGCCATTATCATTTTTGCTCTTTTACTAGCCGTTATTCCTCCATTATTTATGGGTGCTGATTGGAGCGAATG
GATTTATCGAGGTCTAGCTGTATTAGTGGTTGGTTGTCCGTGTGCGTTGGTTATTTCCACGCCTGTTTCGATTGTAACTG
CCATTGGAAATGCAGCGAAAAACGGTGTGTTAATTAAAGGTGGTATTTATTTAGAGGAAGCAGGATCTCTAAAAGTCATC
GCTTTTGATAAAACAGGAACATTAACAAAAGGTGTTCCTTCCGTCACCGATGTGGTCACTTATAATGGCGATGAAAATGA
ACTAATGACCATTACAGCAGCCATTGAAAAAGGCTCACAACATCCACTTGCTTCCGCCATTATAAGAAAAGCAGAAGAAG
ATGGATTGAATTTTAATGATGTATCGGTTGAAGAATTCCAATCCATTACAGGTAAAGGGGTCAAAGCCAAAGTAAATAAC
GCAATGTATTATGTCGGAAGTCCAGGTCTTTTTGAAGAACTTCTTCCAAATGGCATCCAATCAGAAATAAAAGAACAAAT
TACAACCCTTCAAACACAAGGGAAAACGGTCATGATATTAGGGACGGAAAAAGAAATTCTGGCGTTAATTGCCGTGGCAG
ACGAAATAAGAGAATCATCCAAAGAGGTTATTCGAAAACTTCATCAAGTCGGTATTGAAAAAACGGTAATGTTGACAGGG
GATAACCAAAGAACAGCCGAAGCCATCGGAAAACAAGTCGGCGTTTCCGATATTAAAGCCGATTTACTTCCAGAAGATAA
ACTGAATTTCATCAAAGAGCTTCGTGACAAGCATCAAAGCGTGGCGATGGTTGGAGATGGTGTGAACGATGCACCAGCTC
TTGCAGCTTCAACCGTTGGTGTGGCGATGGGCGGTGCTGGAACCGATACAGCCCTAGAAACAGCCGATATTGTCTTAATG
TCTGATGATTTAAGCAAATTGCCATATACGATTAAATTGAGCCGCAAAGCTTTAGCGATTATTAAGCAAAACATTACTTT
CTCTTTAGGGATTAAGGCATTGGCATTACTGTTAATTGTGCCTGGTTGGTTAACGCTATGGTTAGCGATATTTGCCGATA
TGGGAGCAACATTAATCGTAACATTAAACAGCATGCGATTGCTAAAAGTTAAAGAATAA

Protein sequence :
MSEQQAKLSKSEAKTYRVQGFTCANCAAKFENNVKALPGVQDAKVNFGASKITVWGTTTIEELEKAGAFENLKVREDKEK
SVKREPFWKQKENIRVYISAVLLVISWFLGKQYGEEHIFATIGYAAAILIGGYSLFIKGFKNLVRLNFDMNTLMTVAILG
AAAIGEWGEGATVVILFAISEALERYSMDKARQSIESLMDIAPKEALIRRGNEEMMVPVDDIQVGDIMIVKPGQKLAMDG
IVIKGTSTLNQAAITGESVPVTKTVGDEVFAGTLNEEGLLEVKVTKRVEDTTLSKIIHLVEEAQAERAPSQAFVDRFAKY
YTPAIIIFALLLAVIPPLFMGADWSEWIYRGLAVLVVGCPCALVISTPVSIVTAIGNAAKNGVLIKGGIYLEEAGSLKVI
AFDKTGTLTKGVPSVTDVVTYNGDENELMTITAAIEKGSQHPLASAIIRKAEEDGLNFNDVSVEEFQSITGKGVKAKVNN
AMYYVGSPGLFEELLPNGIQSEIKEQITTLQTQGKTVMILGTEKEILALIAVADEIRESSKEVIRKLHQVGIEKTVMLTG
DNQRTAEAIGKQVGVSDIKADLLPEDKLNFIKELRDKHQSVAMVGDGVNDAPALAASTVGVAMGGAGTDTALETADIVLM
SDDLSKLPYTIKLSRKALAIIKQNITFSLGIKALALLLIVPGWLTLWLAIFADMGATLIVTLNSMRLLKVKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 67
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 66
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 65

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA2 YP_007402014.1 putative cadmium-transporting ATPase BAC0298 Protein 4e-118 49
cadA2 YP_007402014.1 putative cadmium-transporting ATPase BAC0092 Protein 1e-102 45