Gene Information

Name : clpC (GHH_c01020)
Accession : YP_007400446.1
Strain : Geobacillus sp. GHH01
Genome accession: NC_020210
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 98986 - 101418 bp
Length : 2433 bp
Strand : +
Note : ATPase subunit of the ClpC-ClpP protease

DNA sequence :
ATGATGTTTGGCAGATTTACGGAACGGGCGCAAAAAGTGCTGGCGCTGGCGCAGGAAGAAGCCATTCGCCTCGGCCATAA
CAATATCGGCACAGAACATATTTTGCTCGGCCTCATCCGCGAGGGCGAGGGGATCGCGGCTAAGGCGCTCATGGCGCTTG
GGCTCGGCCCAGATAAAATTCAAAAAGAAGTCGAATCGCTCATCGGCCGTGGCAGTGAAGTGTCGCATACGATCCACTAT
ACACCGCGGGCGAAAAAAGTCATTGAGCTGTCGATGGATGAAGCGCGGAAGCTCGGCCATTCATACGTCGGCACAGAACA
TATTTTGCTTGGGTTGATCCGCGAAGGCGAAGGGGTGGCCGCCCGCGTGCTGAACAACTTGGGAGTAAGCTTGAACAAAG
CGCGCCAGCAAGTGTTGCAGCTGCTCGGCAGCAATGAGTCGATGTCAGGCCATGGCGGCGGCGCGTCGCATGTGAGCACT
CCGACGCTTGACAGCCTCGCCCGTGATTTGACAGCGATTGCCCGCGAAGGACGGCTGGACCCGGTCATCGGCCGCAGTAA
AGAAATTCAGCGCGTCATTGAAGTATTAAGCCGGCGGACGAAAAATAATCCGGTGTTGATCGGCGAGCCGGGCGTTGGGA
AAACGGCCATTGCTGAAGGGTTAGCCCAACAAATCGTCAATAACGAAGTGCCGGAAACGCTGCGCGACAAGCGGGTCATG
ACGCTCGATATGGGGACGGTCGTCGCCGGAACGAAATACCGGGGGGAATTTGAAGACCGGCTGAAAAAAGTGATGGATGA
AATTCGTCAAGCGGGCAACATCATCTTGTTCATCGATGAGTTGCATACATTAATTGGCGCCGGTGGGGCAGAAGGAGCGA
TCGACGCGTCGAACATCTTGAAACCGGCGTTGGCGCGCGGGGAGCTTCAATGCATCGGCGCGACAACGCTCGATGAATAC
CGGAAATATATTGAAAAAGACGCCGCGCTTGAACGCCGCTTTCAGCCGATTTACGTTGATGAACCGACAGTGGAAGAATC
GATCCAAATTTTAAAAGGGTTGCGCGATCGGTATGAAGCGCACCACCGCGTTTCGATTTCCGACGAGGCGATCGTGCAAG
CCGTCAAATTGTCCGACCGCTACATTACCGACCGTTTCTTGCCGGATAAGGCGATCGATTTGATCGACGAGGCTTGCTCG
AAAGTGCGCCTTCGTTCGTTCACCGCACCGCCGAAATTGAAAGAACTTGAACAAAAGCTCGAGGAAGTGCGGAAAGAAAA
AGACGCGGCCGTGCAAAGCCAAGAATTTGAAAAAGCAGCATCGCTGCGCGATATGGAACAGCGGCTGCGCGAAGAACTGG
AGGAAACGAAACGTGCGTGGAAAGAAAAACAAGGCCAAGAAAATTTGGAAGTGACGGTCGAAGACATCGCCGCGGTCGTC
TCGAGTTGGACCGGCATTCCAGTATCGAAGCTCGCTGAGACGGAAACGGAGCGGCTGCTCAAGCTGGAAGAAATTTTGCA
TTCGCGTGTCGTCGGCCAAGACGAGGCGGTCAAAGCGGTCGCCAAAGCGGTGCGCCGCGCCCGTGCTGGCCTGAAAGACC
CGAAACGCCCGATCGGTTCGTTCATTTTCCTTGGTCCGACCGGCGTTGGGAAAACGGAGTTGGCCCGAGCCTTGGCAGAA
GCGATGTTTGGCGATGAAGACGCCCTCATTCGCATCGATATGTCCGAGTATATGGAAAAACACTCGACATCGCGGCTCAT
CGGGTCGCCGCCGGGGTATGTCGGTTATGAAGAAGGCGGCCAGCTGACGGAAAAAGTGCGCCGCAAGCCGTATTCGGTTG
TCCTGTTAGATGAGATGGAAAAAGCGCATCCGGACGTGTTCAATATTTTGCTGCAAGTGTTGGAAGATGGGCGGCTGACT
GACTCGAAAGGGCGGACGGTCGACTTCCGCAACACGATCATCATCATGACATCCAACGTCGGCGCCGATGCGCTGAAACG
GAATAAGTACGTTGGCTTCAACATTCAAGACGGGAACCAGCAATACAAAGATATGAAAAGCAAAGTGATGGATGAGCTGA
AAAAAGCATTCCGTCCAGAGTTTTTAAACCGGATCGACGAAATCATCGTCTTCCATTCGCTCGAAAAAGACCATCTGAAA
CAAATCGTCCGATTGATGGCCGATACGCTCGTGAAGCGGCTGAAAGAGCAAGACATTGATCTTGAGCTGACGGAGGCCGC
CATTGAGAAAATCGCCGCCGAAGGGTTCGATCCAGAATACGGTGCCCGTCCGCTGCGCCGCGCCTTGCAAAAGCATGTTG
AAGACCGTTTGTCCGAAGAATTGTTAAAAGGCACGATCGCCAAAGGGCAAAAAGTCGTCGTGGATGTCAAAGACGGGGAG
TTTGTCGTATTGTCGAAACAGGCGGTCGTGTGA

Protein sequence :
MMFGRFTERAQKVLALAQEEAIRLGHNNIGTEHILLGLIREGEGIAAKALMALGLGPDKIQKEVESLIGRGSEVSHTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESMSGHGGGASHVST
PTLDSLARDLTAIAREGRLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKYIEKDAALERRFQPIYVDEPTVEESIQILKGLRDRYEAHHRVSISDEAIVQAVKLSDRYITDRFLPDKAIDLIDEACS
KVRLRSFTAPPKLKELEQKLEEVRKEKDAAVQSQEFEKAASLRDMEQRLREELEETKRAWKEKQGQENLEVTVEDIAAVV
SSWTGIPVSKLAETETERLLKLEEILHSRVVGQDEAVKAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
AMFGDEDALIRIDMSEYMEKHSTSRLIGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEMEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTIIIMTSNVGADALKRNKYVGFNIQDGNQQYKDMKSKVMDELKKAFRPEFLNRIDEIIVFHSLEKDHLK
QIVRLMADTLVKRLKEQDIDLELTEAAIEKIAAEGFDPEYGARPLRRALQKHVEDRLSEELLKGTIAKGQKVVVDVKDGE
FVVLSKQAVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 59
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-88 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_007400446.1 ATP-dependent Clp protease VFG0079 Protein 0.0 79
clpC YP_007400446.1 ATP-dependent Clp protease VFG0080 Protein 3e-141 53