Gene Information

Name : ST548_p7785 (ST548_p7785)
Accession : YP_007386813.1
Strain : Enterobacter aerogenes EA1509E
Genome accession: NC_020181
Putative virulence/resistance : Virulence
Product : iron aquisition yersiniabactin synthesis enzyme (Irp2)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 518254 - 524361 bp
Length : 6108 bp
Strand : -
Note : -

DNA sequence :
ATGATTTCTGGCGCACCATCTCAGGATTCGCTGTTACCGGACAACCGCCACGCGGCTGATTACCAACAATTACGCGAGCG
GCTTATACAGGAACTGAATTTAACGCCGCAGCAGTTACATGAAGAGAGCAATCTGATCCAGGCTGGCCTGGATTCAATAA
GATTGATGAGATGGTTACACTGGTTTCGTAAAAATGGCTACCGCCTTACCCTTCGCGAGCTGTATGCCGCCCCCACGCTG
GCGGCATGGAACCAGTTAATGCTCAGCCGGTCGCCGGAGAACGCGGAAGAAGAAACGCCGCCCGACGAATCATCCTGGCC
GAACATGACCGAAAGTACCCCCTTCCCATTGACGCCGGTACAGCACGCCTACCTGACGGGCCGCATGCCGGGGCAGACGC
TTGGCGGCGTGGGTTGCCACCTGTATCAGGAGTTTGAAGGCCATTGTCTGACGGCGTCGCAGCTGGAGCAGGCCATCACG
ACCTTGCTGCAACGCCACCCAATGCTGCATATCGCCTTTCGCCCCGACGGGCAGCAGGTCTGGCTACCGCAACCTTACTG
GAACGGCGTCACCGTTCATGATTTACGCCATAACGACGCTGAAAGCCGCCAGGCCTATCTGGACGCGCTACGCCAGCGCC
TGAGCCACCGTCTTTTACGCGTGGAGATCGGCGAAACGTTTGATTTTCAGCTGACGCTCTTGCCGGACAATCGCCACCGC
CTCCATGTCAATATTGACCTGCTGATTATGGATGCCTCCAGCTTTACGCTTTTCTTCGATGAGCTTAACGCCCTGCTGGC
CGGAGAATCGCTGCCGGCTATCGACACCCGCTATGATTTCCGCTCGTATTTGCTGCAACAGCAGAAGATCAATCAACCAC
TGAGAGACGACGCGCGCGCTTACTGGCTGGCGAAAGCATCGACGCTTCCCCCCGCGCCCGTCTTGCCGCTGGCCTGCGAA
CCCGCCACGCTACGTGAAGTCCGTAATACCCGACGCCGCATGATTGTCCCGGCAACACGCTGGCACGCCTTTAGCAACCG
GGCCGGCGAGTATGGCGTGACGCCGACAATGGCGCTGGCGACCTGTTTTTCTGCCGTGCTGGCTCGCTGGGGCGGCCTGA
CGCGTCTGCTGCTTAACATCACCTTATTCGACCGCCAGCCGCTGCACCCGGCGGTTGGCGCGATGCTTGCCGACTTCACC
AATATTCTTCTGCTGGATACCGCCTGCGACGGCGATACCGTCAGCAATCTGGCGCGTAAAAACCAGCTCACGTTTACGGA
GGACTGGGAGCATCGCCACTGGTCCGGCGTCGAGCTACTCCGTGAACTCAAACGCCAGCAGCGCTACCCCCACGGCGCCC
CGGTGGTATTTACCAGCAATCTGGGGCGTTCCCTCTACAGCAGCCGCGCAGAATCGCCGTTGGGCGAGCCGGAATGGGGC
ATCTCGCAAACGCCGCAGGTCTGGATAGATCATCTGGCGTTCGAGCATCACGGCGAGGTCTGGCTGCAATGGGACAGCAA
CGACGCGCTGTTCCCTCCGGCGTTAGTCGAAACATTGTTCGACGCCTACTGCCAGTTGATTAACCAACTCTGCGATGACG
AAAGCGCCTGGCAAAAGCCGTTCGCAGATATGATGCCCGCCAGCCAGCGCGCGATACGCGAACGGGTCAACGCCACCGGC
GCCCCCATTCCCGAAGGCTTGCTGCATGAAGGCATTTTCCGTATCGCTCTGCAACAGCCGCAGGCGCTGGCGGTAACGGA
CATGCGTTATCAGTGGAATTATCATGAGCTGACAGACTATGCCCGCCGTTGCGCGGGCAGGTTAATCGAGTGCGGGGTTC
AGCCCGGCGATAATGTGGCTATCACGATGTCGAAAGGCGCAGGACAACTTGTTGCGGTTCTGGCCGTCCTGCTGGCCGGG
GCGGTTTACGTTCCGGTTTCGCTGGACCAGCCTGCCGCACGGCGCGAGAAAATCTACGCTGACGCCAGCGTCCGGCTGGT
GCTCATTTGCCAGCACGACGCCAGCGCCTGGTCAGACGATATTCCCGTCCTTGCCTGGCAGCAGGCCATTGAGGCGGAGC
CGATCGTCAACCCGGTGGTACGCGCCCCCACGCAACCGGCCTACATTATCTACACCTCCGGCTCTACCGGCACGCCGAAA
GGGGTAGTCATTTCTCACCGGGGAGCGCTCAACACCTGTTGCGATATCAATACCCGCTATCAGGTTGGCCCGCATGACAG
GGTGCTGGCCCTCTCCGCCCTGCATTTTGATTTATCGGTTTACGACATTTTTGGCGTACTGCGCGCGGGCGGCGCGCTGG
TGATGGTGATGGAAAATCAACGGCGCGATCCTCACGCATGGTGTGAGCTGATCCAGCGCCATCAGGTCACGCTCTGGAAC
AGCGTCCCGGCGCTGTTCGATATGCTGCTGACCTGGTGTGAAGGCTTCGCCGACGCCACGCCGGAAAACCTGCGCGCAGT
GATGCTTTCCGGCGACTGGATCGGGCTTGACCTCCCCGCCCGTTATCGGGCCTTCCGGCCACAAGGACAATTTATCGCGA
TGGGCGGCGCCACCGAGGCGTCTATCTGGTCTAACGCCTGCGAAATTCACGACGTCCCTGCCCACTGGCGCTCCATCCCT
TACGGTTTTCCGCTAGCCAACCAACGCTACCGGGTGGTGGATGAACGGGGCCGGGACTGCCCTGACTGGGTGCCGGGCGA
ATTATGGATTGGCGGTATCGGGGTCGCGGAAGGCTATTTCAACGACCCCCTGCGCAGCGAGCAGCAATTTTTGACGCTCC
CGGACGAGCGCTGGTATCGCACCGGCGATCTCGGCTGCTACTGGCCAGACGGCACAATCGAGTTCCTCGGTCGTCGCGAC
AAGCAGGTCAAAGTCGGAGGATATCGCATCGAGCTGGGCGAAATCGAAAGCGCGCTCAGCCAGCTGGCGGGGGTGAAACA
AGCAACCGTTCTGGCGATCGGCGAAAAAGAAAAAACGCTGGCGGCATACGTTGTTCCTCAGGGCGAGGCTTTTTGCGTTA
CCGATCACCGGAACCCGGCACTGCCGCAGGCGTGGCACACGCTTGCGGGAACGTTGCCCTGTTGCTCCATCTCGCCAGAG
ATCTCCGCAGAACAGGTAGCCGATTTCCTTCAGCATCGCCTGTTAAAACTAAAGCCGGGTCACACCGCTGGCGCCGATCC
TCTCCCCCTGATGAACTCACTCGCTATCCAGCCGCGCTGGCAGGCCGTGGTGGAACGCTGGTTAGCATTTCTGGTGACGC
AACGGCGACTGAAGCCCGCTGCTGAAGGTTATCAGGTCTGCGCTGGTGAAGAACGCGAGGATGAGCACCCGCACTTCAGC
GGACATGATTTAACGTTATCGCAAATTCTTCGCGGCGCCCGTGACGAACTGTCGTTACTGAACGACGCGCAGTGGTCGCC
GGAAAGCCTGGCCTTCAACCATCCGGCCAGCGCCCCGTATATTCAGGAACTGGCGACAATTTGCCAACAGCTTGCACAGC
GCTTACAGCGCCCGGTACGCCTGCTTGAGGTGGGAACCCGCACCGGCCGCGCCGCAGAATCGCTGTTGGCACAGCTCAAC
GCCGGACAGATTGAGTATATCGGGCTTGAGCAGAGCCAGGAGATGCTGCTGAGCGCCCGGCAGAGGCTCGCCCCCTGGCC
TGGCGCTCGTCTGTCTCCCTGGAATGCAGACACGCTGGCGGCGCACGCTCACTCGGCGGACATTATCTGGCTTAATAACG
CCCTGCATCGTCTGCTGCCGGAAGATCCCGGGCTCCTTGCAACATTACAACAGCTTGCCGTTCCCGGCGCGCTGCTCTAC
GTGATGGAGTTTCGCCAGTTAACGCCGTCCGCCTTGCTCAGCACGCTTCTGTTAACCGATGGGCAGCCGGAGGCCTTGCT
GCATAACAGCGCCGACTGGGCGGCATTATTTAGCGCAGCCGCCTTCAACTGTCAGCATGGCGATGAGATCGCGGGGTTAC
AACGCTTCCTCGTACAATGCCCTGACAGGCAGATGCGCCGCGATCCCCGTCAACTTCAGGCCGCCCTCGCCGGGCGCCTG
CCGGGGTGGATGGTGCCGCAACGGATCGTCTTCCTCGACGCCTTACCGTTGACGGCTAACGGGAAGATTGACTATCAGGC
GCTGAAGCGTCGTCATACCCCTGAAGCGGAAAACCCGGCCGAAGCGGATTTACCCCAGGGCGACATTGAAAAACAGGTTG
CCGCCCTCTGGCAGCAACTCTTATCGACTGGCAATGTCACCAGAGAAACCGACTTCTTCCAGCAAGGCGGCGATAGCCTG
CTGGCGACCCGTCTGACCGGGCAACTTCATCAGGCAGGTTATGAAGCGCAATTAAGCGACCTGTTTAATCATCCCCGGCT
GGCGGATTTTGCCGCCACGCTGCGGAAAACCGACGTCCCGGTCGAACAACCATTCGTCCACTCCCCTGAATATCGCTACC
AGCCCTTTGCGCTTACCGACGTGCAGCAGGCTTACCTGGTGGGGCGTCAGCCGGGCTTTGCCCTGGGCGGCGTCGGCTCA
CATTTCTTTGTTGAATTTGAAATTGCCGATCTGGATCTCACCCGGCTGGAGACGGTCTGGAACCGATTAATCGCCCGCCA
CGATATGCTGCGCGCCATCGTGCGTGATGGACAGCAACAGGTGCTCGAACAGACGCCCCCCTGGGTGATACCCGCACACA
CCCTCCATACGCCTGAAGAGGCGTTGCGGGTACGCGAAAAACTGGCGCATCAGGTACTCAACCCCGAAGTGTGGCCGGTA
TTCGATCTCCAGGTCGGATACGTGGACGGGATGCCCGCCCGCCTGTGGCTGTGTCTGGATAACCTGTTGCTTGACGGTCT
GAGCATGCAGATCCTGCTGGCGGAGCTGGAGCACGGCTACCGCTACCCGCAACAGCTGCTTCCGCCGCTGCCCGTCACCT
TCAGGGATTATCTGCAACAACCCTCGCTACAGTCGCCCAATCCAGATTCTCTGGCATGGTGGCAGGCGCAGCTTGATGAT
ATTCCTCCGGCGCCTGCGTTGCCGTTGCGCTGCTTGCCTCAGGAGGTTGAAACACCTCGCTTCGCCCGCCTGAACGGCGC
GCTGGACAGCACGCGCTGGCATCGGCTGAAAAAACGGGCGGCTGACGCCCATCTCACCCCGTCGGCCGTGCTGTTGTCGG
TGTGGTCAACGGTTCTCTCTGCATGGAGTGCGCAGCCTGAGTTCACGCTTAACCTTACGCTTTTCGACAGGCGACCACTG
CACCCGCAAATCAACCAGATTCTGGGCGATTTCACCTCGCTGATGCTGCTGAGCTGGCATCCCGGCGAAAGCTGGCTGCA
CAGCGCACAGTCACTACAGCAGCGGCTGAGCCAGAACCTCAACCACCGCGATGTGTCAGCTATCCGCGTGATGCGTCAAC
TGGCGCAACGGCAAAACGTGCCTGCCGTTCCGATGCCCGTCGTCTTTACCAGCGCGCTGGGCTTTGAGCAGGATAACTTC
CTCGCCCGGCGTAATCTGCTCAAACCGGTCTGGGGCATCTCCCAGACGCCGCAGGTCTGGCTCGATCACCAGGTTTATGA
ATCCGAAGGCGAACTGCGCTTTAACTGGGATTTTGTCGCCGCGCTGTTTCCTGCCGGGCAGGTGGAGCGCCAGTTTGAAC
AGTATTGCGCATTGCTAAACCGAATGGCCGAGGATGAAAGCGGCTGGCAACTGCCGCTCGCCGCGCTGGTGCCTCCCGTT
AAACACGCAGGGCAATGCGCAGAGCGCTCACCGCGCGTATGCCCTGAGCACTCTCAGCCACACATTGCGGCGGACGAGAG
CACCGTCAGCCTGATTTGCGACGCCTTCCGCGAGGTGGTTGGCGAGTCTGTCACGCCCGCAGAAAACTTCTTTGAGGCGG
GCGCAACGTCGCTGAATCTGGTGCAACTGCACGTTTTGTTACAACGTCACGAATTTTCCACCCTGACGTTGCTTGACCTC
TTCACCCACCCTTCTCCTGCCGCCCTGGCCGATTATCTGGCCGGCGTCGCCACGGTGGAGAGAACAAAACGTCCTCGCCC
TGTTCGCCGTCGTCAGCGGCGGATATAG

Protein sequence :
MISGAPSQDSLLPDNRHAADYQQLRERLIQELNLTPQQLHEESNLIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTL
AAWNQLMLSRSPENAEEETPPDESSWPNMTESTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFEGHCLTASQLEQAIT
TLLQRHPMLHIAFRPDGQQVWLPQPYWNGVTVHDLRHNDAESRQAYLDALRQRLSHRLLRVEIGETFDFQLTLLPDNRHR
LHVNIDLLIMDASSFTLFFDELNALLAGESLPAIDTRYDFRSYLLQQQKINQPLRDDARAYWLAKASTLPPAPVLPLACE
PATLREVRNTRRRMIVPATRWHAFSNRAGEYGVTPTMALATCFSAVLARWGGLTRLLLNITLFDRQPLHPAVGAMLADFT
NILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQRYPHGAPVVFTSNLGRSLYSSRAESPLGEPEWG
ISQTPQVWIDHLAFEHHGEVWLQWDSNDALFPPALVETLFDAYCQLINQLCDDESAWQKPFADMMPASQRAIRERVNATG
APIPEGLLHEGIFRIALQQPQALAVTDMRYQWNYHELTDYARRCAGRLIECGVQPGDNVAITMSKGAGQLVAVLAVLLAG
AVYVPVSLDQPAARREKIYADASVRLVLICQHDASAWSDDIPVLAWQQAIEAEPIVNPVVRAPTQPAYIIYTSGSTGTPK
GVVISHRGALNTCCDINTRYQVGPHDRVLALSALHFDLSVYDIFGVLRAGGALVMVMENQRRDPHAWCELIQRHQVTLWN
SVPALFDMLLTWCEGFADATPENLRAVMLSGDWIGLDLPARYRAFRPQGQFIAMGGATEASIWSNACEIHDVPAHWRSIP
YGFPLANQRYRVVDERGRDCPDWVPGELWIGGIGVAEGYFNDPLRSEQQFLTLPDERWYRTGDLGCYWPDGTIEFLGRRD
KQVKVGGYRIELGEIESALSQLAGVKQATVLAIGEKEKTLAAYVVPQGEAFCVTDHRNPALPQAWHTLAGTLPCCSISPE
ISAEQVADFLQHRLLKLKPGHTAGADPLPLMNSLAIQPRWQAVVERWLAFLVTQRRLKPAAEGYQVCAGEEREDEHPHFS
GHDLTLSQILRGARDELSLLNDAQWSPESLAFNHPASAPYIQELATICQQLAQRLQRPVRLLEVGTRTGRAAESLLAQLN
AGQIEYIGLEQSQEMLLSARQRLAPWPGARLSPWNADTLAAHAHSADIIWLNNALHRLLPEDPGLLATLQQLAVPGALLY
VMEFRQLTPSALLSTLLLTDGQPEALLHNSADWAALFSAAAFNCQHGDEIAGLQRFLVQCPDRQMRRDPRQLQAALAGRL
PGWMVPQRIVFLDALPLTANGKIDYQALKRRHTPEAENPAEADLPQGDIEKQVAALWQQLLSTGNVTRETDFFQQGGDSL
LATRLTGQLHQAGYEAQLSDLFNHPRLADFAATLRKTDVPVEQPFVHSPEYRYQPFALTDVQQAYLVGRQPGFALGGVGS
HFFVEFEIADLDLTRLETVWNRLIARHDMLRAIVRDGQQQVLEQTPPWVIPAHTLHTPEEALRVREKLAHQVLNPEVWPV
FDLQVGYVDGMPARLWLCLDNLLLDGLSMQILLAELEHGYRYPQQLLPPLPVTFRDYLQQPSLQSPNPDSLAWWQAQLDD
IPPAPALPLRCLPQEVETPRFARLNGALDSTRWHRLKKRAADAHLTPSAVLLSVWSTVLSAWSAQPEFTLNLTLFDRRPL
HPQINQILGDFTSLMLLSWHPGESWLHSAQSLQQRLSQNLNHRDVSAIRVMRQLAQRQNVPAVPMPVVFTSALGFEQDNF
LARRNLLKPVWGISQTPQVWLDHQVYESEGELRFNWDFVAALFPAGQVERQFEQYCALLNRMAEDESGWQLPLAALVPPV
KHAGQCAERSPRVCPEHSQPHIAADESTVSLICDAFREVVGESVTPAENFFEAGATSLNLVQLHVLLQRHEFSTLTLLDL
FTHPSPAALADYLAGVATVERTKRPRPVRRRQRRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp2 YP_001006815.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 YP_002346902.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 NP_669706.1 HMWP2 nonribosomal peptide synthetase Virulence HPI Protein 0.0 99
irp2 YP_070124.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 YP_853075.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 0.0 99
irp2 NP_993007.1 yersiniabactin biosynthetic protein Virulence HPI Protein 0.0 99
irp2 CAA21390.1 - Virulence HPI Protein 0.0 99
PMI2599 YP_002152317.1 non-ribosomal peptide synthase Not tested Not named Protein 0.0 41