Gene Information

Name : ST548_p5818 (ST548_p5818)
Accession : YP_007388780.1
Strain : Enterobacter aerogenes EA1509E
Genome accession: NC_020181
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase [enterobactin] siderophore
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 2519053 - 2520660 bp
Length : 1608 bp
Strand : -
Note : -

DNA sequence : 
ATGATTGCATTTACCCGTTGGCCGGAAGAGTTTGCGGCCCGCTATCGTCAAAAAGGCTACTGGCAGGATCTGCCGTTAAC
CAATCTGATTACTCGTCATGCGGACAATGACGCCGTGGCGATTATCGACGGCGAGCGGCAGATTAGCTACCGCCAGTTTA
ACCAACTGGTGGATAACCTCGCGTCCTCCCTGCAGCATCAGGGACTCAAGCGCGGAGAAACCGCGCTGGTGCAGCTTGGC
AACGTCGCCGAGTTCTACATTACCTTCTTTGCGCTGCTGCGCATCGGCGTCGCACCGGTTAACGCTTTGTTTAGCCATCA
GCGCAGCGAACTCAACGCCTATGCCGCGCAGATTAAACCGGTGCTGCTGATTGCCGATCGCGAGCACGCGCTGTTTGCTG
ACGATAGTTTCCTTAATGGTTTTATCGCTGAGCATCCTTCGCTGCGCGTCGCGCTGCTGCGTAACGATGGCGGCGAGCGC
GACCTGGCAACGGAAATTAACCGCACGGCGGATAACTTTGTCGCCAATCCGACGCCGGCTGACGAAGTGGCTTTTTTCCA
GCTCTCCGGCGGCAGCACCGGGACGCCGAAGCTTATTCCGCGAACCCATAACGATTACGACTACAGTATCCGCCGCAGCA
ACGAGATCTGCGGGATTAACGCCGACACGCGCTATCTCAACGCGCTGCCGGCGGCGCACAACTATGCGATGAGCTCGCCG
GGATCGCTGGGCGTCTTTCTCGCCGGCGGCCGGGTGATCCTCGCCGCTGACCCGAGCGCCACGTTGTGTTTCCCGCTGAT
CGAAAAACATCAGATTAACGTCGCGTCGCTGGTGCCGCCGGCGGTCAGCCTGTGGCTGCAGGCTATTCATGAATGGGGCA
GCAACGCGCAACTGCAATCGCTGAAGCTGCTGCAGGTTGGCGGAGCGCGCCTGTCCGCGACGCTCGCCGCGCGTATCCCG
GCGGAAATCGGCTGCCAGCTGCAGCAGGTGTTCGGCATGGCGGAAGGGCTGGTTAACTACACCCGCCTCAACGATAGCCC
GCAGCGGATTATCAACACCCAGGGTTGCCCGATGTGTCCTGACGACGAAGTGTGGGTGGCGGATGCCGACGGTAACCCGC
TGCCGCGCGGCGAAGTGGGCCGTCTGATGACCCGCGGCCCTTATACCTTCCGCGGCTATTACAACAGCCCGCAACATAAC
GCTGAAGCCTTTGATGCCGATGGATTTTACTGCTCCGGCGATCTGATTTCGATCGATGAAGATGGCTATATCACCGTCCA
GGGCCGGGAAAAAGATCAGATCAACCGCGGTGGCGAGAAGATCGCCGCTGAAGAAATAGAAAACCTGCTGCTGCGCCATG
AGGCGGTGATCCACGCCGCGCTGGTTAGCATTGAAGACAATCTGCTGGGCGAGAAGAGCTGCGCTTATCTGGTGGTGACA
TCGCCGCTGCGCGCCGTCGCGGTGCGCCGCTTCCTGCGCGAGCAGGGCGTGGCGGAATTTAAATTGCCGGATCGCGTGGA
GTGCGTTGCCGCGCTGCCGCTGACGCCGGTGGGCAAAGTCGATAAAAAACAATTACGTCAGTGGCTGGCCGAAGGCAAGC
TGGGCTGA

Protein sequence : 
MIAFTRWPEEFAARYRQKGYWQDLPLTNLITRHADNDAVAIIDGERQISYRQFNQLVDNLASSLQHQGLKRGETALVQLG
NVAEFYITFFALLRIGVAPVNALFSHQRSELNAYAAQIKPVLLIADREHALFADDSFLNGFIAEHPSLRVALLRNDGGER
DLATEINRTADNFVANPTPADEVAFFQLSGGSTGTPKLIPRTHNDYDYSIRRSNEICGINADTRYLNALPAAHNYAMSSP
GSLGVFLAGGRVILAADPSATLCFPLIEKHQINVASLVPPAVSLWLQAIHEWGSNAQLQSLKLLQVGGARLSATLAARIP
AEIGCQLQQVFGMAEGLVNYTRLNDSPQRIINTQGCPMCPDDEVWVADADGNPLPRGEVGRLMTRGPYTFRGYYNSPQHN
AEAFDADGFYCSGDLISIDEDGYITVQGREKDQINRGGEKIAAEEIENLLLRHEAVIHAALVSIEDNLLGEKSCAYLVVT
SPLRAVAVRRFLREQGVAEFKLPDRVECVAALPLTPVGKVDKKQLRQWLAEGKLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-90 42
ybtE CAA21394.1 - Virulence HPI Protein 5e-90 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-90 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 4e-90 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 6e-90 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-90 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-90 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 5e-90 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-90 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ST548_p5818 YP_007388780.1 2,3-dihydroxybenzoate-AMP ligase [enterobactin] siderophore VFG0932 Protein 0.0 81
ST548_p5818 YP_007388780.1 2,3-dihydroxybenzoate-AMP ligase [enterobactin] siderophore VFG0168 Protein 3e-110 45