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Name : APECO78_16850 (APECO78_16850) Accession : YP_007382535.1 Strain : Escherichia coli APEC O78 Genome accession: NC_020163 Putative virulence/resistance : Unknown Product : HsdR family type I site-specific deoxyribonuclease Function : - COG functional category : - COG ID : - EC number : - Position : 3509784 - 3513023 bp Length : 3240 bp Strand : + Note : COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases DNA sequence : ATGGCAAAGATGACCGAATCCGATATTGAAGTAATGGCAATTGAGCACCTGCAAGGGCTGGGCTATGAGTATGTTTACGG CCCGGACATTGAACCCAGTGGAATCAATCCGTTACGTAGCTATCAGCAGGTTATCCTTGAAGATAAAGTGCGTACAGCAT TGCAACGAATTAACCCGCACCTTAGTGAGCAGAAGTGTGAAGAAGCTCTAAAACAGGTGATGCAGATCAGCTCACCTGAC CTAATGGCAAACAATCTAACCTTTCATCGCCTTTTGACCGAAGGAATCAATATCGAAGTCAGCAAGGATGGTAATACACA AGGAGAACTGGCCAGCCTGATCGACTTTAACGATCCCACTAATAATGCATTTCTGGTCATTAATCAGCTCACCATCAAAG AAGGCAACCATACCCGCCGACCTGATCTTATTTTATTCATCAATGGCCTGCCATTAGTCGTTATCGAACTTAAAAATGCC GCTGACGAAAATGCAACGGTAACAGGTGCCTATAATCAGATTAAAACCTATCAGAACCAAATCCCCGGTCTGTTTAACTA CAATGCTTTTAATGTGATATCTGACGGGCTGGAAGCCAAAGCGGGGACGGTTTCTGCCGATTTCAGTCGTTATATGACGT GGAAAACTGCTAACGGTAAAACGCAAGCCACCAGTACCCAACCACAGCTTGAAGTTTTATTACAGGGGTTGCTTAATCCT GTAACGCTGCTGGATATAATCCGCCACTTTATCGTGTTTGAGGCCAGCAAACATGAAGACAGCAAAGGGATTATCAGTAT CCGTACTGTTAAAAAAATGGCGGCTTATCACCAGTACTACGCGGTCAATGCAGCAGTTCTTTCCACTATTCGTGCCTCAG CGGTGAATGCGGACTCCCCCTCTGCCGAAGTGGCACTGCGCCAGCAGGGACGTAACAGTAAAGATCTTGTTAATGCGCAA AAAACCGGAGATCGCAAAGCGGGCGTAGTCTGGCATACTCAGGGTTCCGGTAAATCGCTTTCGATGGTGTTTTATACCGG GAAAATTGTGCTGGCGCTGGATAATCCGACAGTTGTTGTGATTACTGACCGTAACGACTTAGATGATCAGCTATTCGGTA CGTTCTCTTCCGCGACCCAGCTACTTCGTCAGACACCAAAACAGGCCAACAACCGGGAAGAACTCAAAGAATATTTGCGT GTCGCCTCTGGCGGTGTGGTGTTTACTACTATTCAAAAATTCCAGCCTGATGATGGCAGCAATATCTATGAGTTGTTGTC AGACAGAACCAATATTGTCGTTATCGCTGATGAAGCACACCGTTCCCAGTACGGTTTCAGCGCCAAAGAAGTTGACGTGA AAGACAGCGAAGGCAACGTAACAGGTAAACGCACCGTTTACGGCTTTGCCAAATATATGCGTGATGCCTTACCTAATGCG ACCTATCTCGGCTTTACCGGAACCCCCATAGAAAAAACGGACGTCAACACGCCTGCTGTTTTTGGTAACTATGTTGATAT CTACGATATCTCGCAGGCCGTTGAAGATGGTGCAACAGTTCGTATCTTTTATGAAAGCCGTCTTGCCAAAATTGCCATCA GTGATGAAGGTCGTCAGCTTATTGAAGACTTTGATGATGAGTTTAACGAGGACGAACTGACGCTCACGCAAAAAGAACGT TCTAAATGGGCCAGAATCGAAGGTTTGATTGGCAGTTCAAAACGTATTAAAGCGATTGCGGCGGATATGGTTCTGCACTT TGAGCAGCGCTTAAAATCCAATGCCGATCATGGTAAGGGCATGATTGTTACCATGTCCCGCCGTATTGCTGCTGAACTAT ATAAAGAAATCATAGCCTTAAAACCTGAATGGCACAGCGATGATTTAAATGACGGTATAATAAAAGTCGTCATGACCTCT TCTGCTGCTGACGGGCCAGAAATTGCCAAACACCACACCACAAAAAAAGAACGTCAGGTTCTGGCTAACCGTATGAAGGA TGACGACGACAAGCTGAAACTGGTGATAGTGCGTGATATGTGGTTAACCGGCTTCGACGCTCCCAGCATGCATACGCTGT ATATCGACAAACCAATGAAAGGCCACAACCTTATGCAGGCAATTGCCCGTGTGAACCGTGTGTATAAAGATAAGATAGGC GGTCTGGTTGTTGACTATCTGGGCATTGCCTCTGATTTAAAAGAAGCCCTCTCCTTTTACTCTGATGCAGGTGGACGTGG AGATCCTGCTGAGGTTCAGGAAGAAGCCGTAACGCTCATGCAGGAAAAGCTGGAAATCCTGGAAGGCATGATGCATGGAT ACGATTACAAAGCTTACTTTGCCGCAACTACCTCACAACGCCTGACAATTATTCTTGAATCAGAAAACCATATTTTAGGG CTGGATAACGGTAAAGGTAAAATGCGTTTCCTCGCTGCGGTTGCAGCCTTATCGCAGGCATTTGCATTGGCGACACCGCA CGATAAAGCAATGGAAGCGGCACCCGAAGTAGCATTCTTCCAGGCAGTAAAAGCCAGACTGAATAAATTTACTGAAAACT CAGACGGATCAGAAGAAGAACACAATGACAGTCTCGAAGTTCGGGTAAAACAGACTATCGATCAGGCTCTGGTTACCGAT AAAGTTGTTGATATTTTTGACGCTGCTGGGATACAAAAACCTGATATTTCCGTTCTTTCTGAAGAATTCCTTCAGGAAAT GAAGGATTACCAACACAGAAATATTGCTTTGGAAACGCTTAAAAAACTGCTTTCTGACGAGATCAAGGTTCGCTCGAATC AAAGTATCACCCAAGGCAAAAAACTGATTGATATGCTGACCTCTGCAATCAATGGCTACCAGAACAAGGTACTGACCGCA GCGGAGGTAATTGATGAGCTAATCAAGCTTGCCAAGACTATCCAGGAATCTGACAGCCTTGCCAGCCAGTTAAACCTCAG CGCTTATGAATATGCCTTCTATTCTGCTGTTGCAGATAACGACAGTGCTCGCGAGTTAATGGAAAAGGAAAAACTACGAG AACTGGCAGTCGTACTTACGGAGGCTATCCGCAACAATGTCAGTCTTGACTGGACAGTGAAAGAAGCAGCAAGAGCAAAA ATTCGCGTGGTGGTAAAACGTCTGCTCAAAAAATATGGTTATCCGCCTGATATGTCATTGCTCGCCACAGAGACTGTTTT GAAGCAGGCTGAACTTTTAGCTGGAGAATTAGGAAAATGA Protein sequence : MAKMTESDIEVMAIEHLQGLGYEYVYGPDIEPSGINPLRSYQQVILEDKVRTALQRINPHLSEQKCEEALKQVMQISSPD LMANNLTFHRLLTEGINIEVSKDGNTQGELASLIDFNDPTNNAFLVINQLTIKEGNHTRRPDLILFINGLPLVVIELKNA ADENATVTGAYNQIKTYQNQIPGLFNYNAFNVISDGLEAKAGTVSADFSRYMTWKTANGKTQATSTQPQLEVLLQGLLNP VTLLDIIRHFIVFEASKHEDSKGIISIRTVKKMAAYHQYYAVNAAVLSTIRASAVNADSPSAEVALRQQGRNSKDLVNAQ KTGDRKAGVVWHTQGSGKSLSMVFYTGKIVLALDNPTVVVITDRNDLDDQLFGTFSSATQLLRQTPKQANNREELKEYLR VASGGVVFTTIQKFQPDDGSNIYELLSDRTNIVVIADEAHRSQYGFSAKEVDVKDSEGNVTGKRTVYGFAKYMRDALPNA TYLGFTGTPIEKTDVNTPAVFGNYVDIYDISQAVEDGATVRIFYESRLAKIAISDEGRQLIEDFDDEFNEDELTLTQKER SKWARIEGLIGSSKRIKAIAADMVLHFEQRLKSNADHGKGMIVTMSRRIAAELYKEIIALKPEWHSDDLNDGIIKVVMTS SAADGPEIAKHHTTKKERQVLANRMKDDDDKLKLVIVRDMWLTGFDAPSMHTLYIDKPMKGHNLMQAIARVNRVYKDKIG GLVVDYLGIASDLKEALSFYSDAGGRGDPAEVQEEAVTLMQEKLEILEGMMHGYDYKAYFAATTSQRLTIILESENHILG LDNGKGKMRFLAAVAALSQAFALATPHDKAMEAAPEVAFFQAVKARLNKFTENSDGSEEEHNDSLEVRVKQTIDQALVTD KVVDIFDAAGIQKPDISVLSEEFLQEMKDYQHRNIALETLKKLLSDEIKVRSNQSITQGKKLIDMLTSAINGYQNKVLTA AEVIDELIKLAKTIQESDSLASQLNLSAYEYAFYSAVADNDSARELMEKEKLRELAVVLTEAIRNNVSLDWTVKEAARAK IRVVVKRLLKKYGYPPDMSLLATETVLKQAELLAGELGK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 47 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 46 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 46 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 46 |
