Gene Information

Name : metB (MULP_04603)
Accession : YP_007370641.1
Strain : Mycobacterium liflandii 128FXT
Genome accession: NC_020133
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase MetB
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 5013097 - 5014263 bp
Length : 1167 bp
Strand : -
Note : -

DNA sequence :
ATGAAGGACGATCACAAGGCGCAGCACCGGTTCGCCGGACTCGCAACACGAGCCATTCATTCCGGCTATCGCCCGGACCC
GGCGACCGGAGCCGTCAACGCTCCGATCTATGCCAGCAGCACCTTCGCCCAGGATGGTGTCGGCGGGCTTCGGGGCGGCT
ATGAGTATGCGCGAACCGGCAGTCCGACTCGCACCGCCTTGGAAGCCGCGCTTGCCGCGGTTGAAGACGCGGCGTTCGGG
CGTGCGTTCAGTTCCGGCATGGCCGCCGCCGACTGCGCGCTGCGGGCAATGCTGCGACCGGGTGACCATGTCGTCATCCC
CGACGACGCCTACGGCGGCACCTTCCGGTTGATTGACAAGGTCTTCACCGGGTGGAACGTCGAGTACACACCGGTAGCCC
TGGCGGATCTGGATGCGGTGCGTGCGGCGATAAGGCCAACCACCCGACTGATTTGGGTGGAAACACCGACCAATCCGCTG
CTGTCGATCGCCGACATCGCCGGCATCGCCCAGCTGGGTGCGGACAGCTCGGCGAAAGTTCTGGTGGACAACACCTTCGC
ATCTCCGGCGCTGCAGCAGCCGCTATCGCTGGGCGCCGACGTGGTGCTGCATTCCACCACCAAATACATCGGTGGTCACT
CCGATGTGGTGGGTGGCGCACTGGTGACCAATGACGAAGAGCTGGACCAGTCTTTTGCCTTCTTGCAGAACGGGGCGGGC
GCGGTGCCGGGCCCGTTCGACGTGTACCTGACCATGCGCGGCCTGAAAACCCTGGTCCTGCGCATGCAGCGGCATAGTGA
AAATGCCGCTGCCGTGGCGGAATTCCTCGCCGAACATCCCGCGATCAGCACCGTGTTGTACCCAGGGCTGCCCAGTCACC
CCGGCCATGCCGTGGCGGCGCGGCAGATGCGCGGGTTTGGCGGCATGGTTTCGGTGCGGATGCGAGCCGGCCGCACCGCC
GCCGAACAGCTGTGCGCCAAGACGAACATCTTCATCCTGGCCGAATCGCTAGGCGGTGTGGAGTCGCTGATCGAGCATCC
CAGCGCGATGACTCACGCGTCGACCGCGGGTTCGCAGCTGGAAGTGCCCGATGACCTGGTGCGGCTGTCGGTCGGTATCG
AAGACGTTGCCGATCTCCTCGACGACCTCAAACAGGCGCTGGGCTAA

Protein sequence :
MKDDHKAQHRFAGLATRAIHSGYRPDPATGAVNAPIYASSTFAQDGVGGLRGGYEYARTGSPTRTALEAALAAVEDAAFG
RAFSSGMAAADCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTGWNVEYTPVALADLDAVRAAIRPTTRLIWVETPTNPL
LSIADIAGIAQLGADSSAKVLVDNTFASPALQQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAG
AVPGPFDVYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAARQMRGFGGMVSVRMRAGRTA
AEQLCAKTNIFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDVADLLDDLKQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-70 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-71 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-50 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_007370641.1 cystathionine gamma-synthase MetB BAC0207 Protein 3e-59 42