Gene Information

Name : mbtA (MULP_03948)
Accession : YP_007370066.1
Strain : Mycobacterium liflandii 128FXT
Genome accession: NC_020133
Putative virulence/resistance : Virulence
Product : bifunctional enzyme MbtA: salicyl-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.-.-.-
Position : 4288529 - 4290181 bp
Length : 1653 bp
Strand : +
Note : -

DNA sequence : 
GTGCCTGTTACATCCGCCCAGCCGCCTCGACCGGGGCCGGTGGCCGGGTTCATTCCGTACCCACCCGAACGAGTGGCCAG
CTACCGCGCCGCCGGTTATTGGACCGGTCGCAGCATCGGCTCGCTGTTGCGGCAAGCGGCCGCACGCTGGCCTGACCGAG
TGGGTGTGGTCGACGCCGGCGCCAGCCATACGTTCTGCGAACTGGACACACTGGCCGATCGAGCCGCCGCGGGCTTCGTT
TCGCTGGGCATCGCACCGGGCGACCGGGTGCTGCTGCAGTTACCCAATTCGTGCCGGTTCGCGGTCGCCTTGTTCGGCCT
GTTGCGCGCCGGAGCCATCCCGGTGATGTGCCTGCCCGGACACCGGCTGGCAGAACTGCACCACTTCGCCGAGGTCAGCG
GTGCGGTGGGTTTGATCGTCGCGCAGCACGCCGGCGGCTTCGACTACCGGTCGATGGCCGAGCGGTTGGTCGCCGCTCAC
CCCCAGTTGCGCCACGTCATCATCGACGGCGAGTCCGGGCCCTTTCTGCCGTGGTCGTCGCTGTCCGAAGGCGCCACACC
CGACATCGATGTCGACACCACATCGCCCGCCTTGTTACTCGTCTCAGGTGGCACCACCGGCACTCCGAAACTGATCCCCC
GAACACACGACGACTACGTCTACAACGCCACCGCGAGTGCGCAGTTGTGCCGGCTGACCGCTGACGACGTGTACCTCGTG
TCGCTGCCGGCGGCGCACAACTTCCCGTTGGCATGTCCGGGCATACTCGGCTCGATGGCCGTCGGCGCCACCATCGTTTT
CAGCACCGACCCCAGCCCGGAGGCCGCCTTCACCTTGATCGAGCGCCACGGCGTCACCGTCACGGCGCTGGTACCCGCGC
TGGCCAAACTGTGGACCCAGGCCTGTGATTGGGAGCCGGTAACCCCGAAGTCTTTGCGGCTATTGCAAGTTGGTGGCTCC
AGATTGGAGCCCGAGGATGCTCGCCAGGCACGAGAGGCATTGACCCCGGGGCTGCAACAGGTCTTCGGGATGGCCGAAGG
ACTGCTGAACTTCACCCGCCTCGAAGATCCGCCGGACCTCCTCGAGCACACCCAGGGCCGGCCCCTGTGCTCCGCTGACG
AATTGCGCATTGTCGACGGCGCGGGCGCGCCGGTGGCTCCCGGCGCAGAGGGCGAGCTACTGGTGCGCGGTCCCTACACC
ATCAACGGCTACTTCTGCGCCGACCGAGACAACGAGCGCTGCTTCGATCCAGCCGGCTTCTATCGCAGCGGCGACTTGGT
CCGACTCCGCGACGACGGCTACCTGCAGGTCACCGGGCGCGTCAAAGACGTCATCTGCCGCTGCGGTGAGACCATCTCGG
CCCAGGACCTCGAAGAACAGTTGCTCAGCCACCCGGCGATCCGCTCGGCCGCGGCGGTGCCACTGCCGGACCCGGATATG
GGCGAGCTGATCTGCGCTGCAATTGTTTTCGCGGGGCCACCGCAGACGCCGCAGACCTTGTCGGGACTCAATGACTATCT
CGAGCAGCGTGGCGTGGCCGCACATATCCGCATCGATCGGCTGGTCGCGATGCCGTCGCTGCCGACCACACCGGTGGGAA
AGATCGACAAGAAGGCGATCGCGAGCCAGATCCTGACAACCACGGCGACCTGA

Protein sequence : 
MPVTSAQPPRPGPVAGFIPYPPERVASYRAAGYWTGRSIGSLLRQAAARWPDRVGVVDAGASHTFCELDTLADRAAAGFV
SLGIAPGDRVLLQLPNSCRFAVALFGLLRAGAIPVMCLPGHRLAELHHFAEVSGAVGLIVAQHAGGFDYRSMAERLVAAH
PQLRHVIIDGESGPFLPWSSLSEGATPDIDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQLCRLTADDVYLV
SLPAAHNFPLACPGILGSMAVGATIVFSTDPSPEAAFTLIERHGVTVTALVPALAKLWTQACDWEPVTPKSLRLLQVGGS
RLEPEDARQAREALTPGLQQVFGMAEGLLNFTRLEDPPDLLEHTQGRPLCSADELRIVDGAGAPVAPGAEGELLVRGPYT
INGYFCADRDNERCFDPAGFYRSGDLVRLRDDGYLQVTGRVKDVICRCGETISAQDLEEQLLSHPAIRSAAAVPLPDPDM
GELICAAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIRIDRLVAMPSLPTTPVGKIDKKAIASQILTTTAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-95 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-94 46
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-94 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-94 46
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-94 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-94 46
ybtE CAA21394.1 - Virulence HPI Protein 2e-94 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-95 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-94 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mbtA YP_007370066.1 bifunctional enzyme MbtA: salicyl-AMP ligase VFG1817 Protein 0.0 72
mbtA YP_007370066.1 bifunctional enzyme MbtA: salicyl-AMP ligase VFG0168 Protein 1e-87 43