Gene Information

Name : pykA (MULP_03197)
Accession : YP_007369424.1
Strain : Mycobacterium liflandii 128FXT
Genome accession: NC_020133
Putative virulence/resistance : Virulence
Product : pyruvate kinase PykA
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 3473996 - 3475414 bp
Length : 1419 bp
Strand : -
Note : -

DNA sequence :
GTGACTAGACGCGGAAAGATCGTCTGCACCCTCGGGCCGGCTACGCAACAGGACGACTTGGTCAAAGAGCTGGTCGAAGC
CGGAATGGACGTCGCCCGAATGAACTTCAGCCACGGCGACTACGCGGATCACGAAGCCGCATATGAACGCGTGCGTGCTG
CCTCTGACGCCACGGGGCGTGCGGTCGGCGTGCTCGCCGATCTGCAAGGCCCGAAGATCAGGTTGGGCCGCTTCGCTGAT
GGGCCGACCTATTGGGCTGACGGGGACACGGTCCGGATCACGGTCGAGGAGTGTGAAGGGTGCCGTGACCGGGTATCCAC
CACCTACAAGAGGCTGGCCCAGGATGCGGTAGCCGGTGACCGAGTGCTCGTTGATGACGGCAAGGTCGGATTGATCGTCG
ATCACATCGACGGCAACGACGTGGTCTGCACAGTCGTAGAAGGCGGCCCGGTCAGCAACAACAAGGGAATCTCCCTGCCG
GGGATGAATGTATCTGCGCCGGCGCTATCGGAGAAGGACATCGACGACCTCACGTTCGCGCTCAACCTGGGTGTCGACAT
GGCCGCGCTGTCCTTCGTGCGGTCGCCTTCGGACGTGGAACTCGTGCATGAGGTGATGGACCGGATCGGCCGGCGAGTTC
CGGTGATCGCGAAGCTGGAAAAGCCCGAAGCGATCGACAATCTCGAAGCCATCGTGTTGGCATTCGACGCCGTCATGGTG
GCCCGCGGCGACCTGGGGGTAGAGCTGCCGCTGGAAGAGGTCCCGCTGGTACAGAAGCGGGCCATCCAGATCGCCCGGGA
GAACGCCAAACCGGTGATCGTGGCGACCCAGATGCTCGACTCGATGATCGAGAACTCGCGGCCCACCCGTGCCGAGGCCT
CTGACGTCGCCAACGCCGTGCTTGACGGCGCCGATGCCCTGATGCTGTCCGGTGAGACCTCGATGGGCAAGTACCCACTT
GCTGCGGTCCGGACGATGTCGCGCATCGTCTGCGCGGTTGAAGAGAACTCGACGGCGGCCCCGCCGTTGACCCATATGCC
GCGCACCAAGCGGGGAGTGATCTCCTATGCGGCCCGCGACATCGGTGAACGACTCGACGCCAAGGCGTTGGTCGCCTTCA
CTCAGTCCGGCGATACCGTGCGACGGCTTGCTCGGCTGCATACCCCATTGCCGCTGCTGGCCTTCACCGCTTGGCCCGAG
GTGCGCAGTCAGCTCGCGATGACCTGGGGCACCGAGGCTTTCATCGTCCCGGAGATGGACTCGACTGACGGCATGATTCG
GCAGGTCGACAAATCGCTGCTAGAACTCGGCCGCTACAAGCGTGGTGATCTGGTGGTCATCGTCGCGGGTGCACCGCCGG
GGACCGTGGGTTCGACCAATCTGATTCACGTGCACCGGATCGGTGAGGACGACGTCTAA

Protein sequence :
MTRRGKIVCTLGPATQQDDLVKELVEAGMDVARMNFSHGDYADHEAAYERVRAASDATGRAVGVLADLQGPKIRLGRFAD
GPTYWADGDTVRITVEECEGCRDRVSTTYKRLAQDAVAGDRVLVDDGKVGLIVDHIDGNDVVCTVVEGGPVSNNKGISLP
GMNVSAPALSEKDIDDLTFALNLGVDMAALSFVRSPSDVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEAIVLAFDAVMV
ARGDLGVELPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSGETSMGKYPL
AAVRTMSRIVCAVEENSTAAPPLTHMPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPE
VRSQLAMTWGTEAFIVPEMDSTDGMIRQVDKSLLELGRYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-70 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_007369424.1 pyruvate kinase PykA VFG0479 Protein 5e-71 41