Gene Information

Name : fliI (LAW_00883)
Accession : YP_007365962.1
Strain : Lawsonia intracellularis N343
Genome accession: NC_020127
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1062588 - 1063907 bp
Length : 1320 bp
Strand : -
Note : -

DNA sequence :
ATGGGACTTACACCAAAAGAATGCCAAAAACTGCTAAAAGAAAGCAATCCATTACGTGTTTATGGTAAAGTAAATAAAGT
AGTTGGGTTGGTTGCTGAAGGAACAGGGTTAAAGTCGCCTCTAGGTGCTGTATGTCATATGCTCTCTGGGAATGATGAAC
ATGGAGAGGCTATTGCTGCAGAAGTGGTAGGTTTCCGTGAAGGGAATCTGTTATTTATGCCTTATGGAGAAATGAGAGGT
ATCCAACCTGGAAGTCTTATTAGAAATACTAGTTTACCTCCTGTGTTCCCCGTAGGTAAAGAGATTCTTGGACATGCATT
CAATGCTTTTGGAGAACCTCTTAGTGGCGGAAATCCAATTATACCAGAAAAATTAATCCCTCTTTATTCAAATCCTCCAT
CACCACTTGAACGACCACGTATTAAAGATCCTCTTGATGTAGGGGTACGTGCTATTAACTCCATGATTACCCTTGGTAAA
GGACAACGAGTAGGTATTATGGCAGGATCTGGTGTTGGAAAGTCAACTCTTATGGGAATGATGGCTCGGTACACTTCTGC
AGATGTTAATGTAATAGGGTTGATAGGAGAACGTGGTCGAGAAGTTGTTGAGTTTATGGAAAAAGAGCTTGGTCCAGAAG
GAATGACACGATCTGTTCTTATTATAGCTACATCTGATCAATCTCCTCTTGTACGTATGCGTGCCGCTTATGCTGCAACA
GCAGTAGCAGAATATTTTCGAGATCAAGGGAAAGATGTTCTGCTTATGATGGATTCAGTAACCCGATTTGCTATGGCAGC
GCGTGAAATTGGACTTGCTGTTGGTGAACCTCCTACTACAAAAGGATATACACCCACAGTTTTTGCACAACTACCTAAAC
TTCTTGAAAGAACAGGTCGTAGTAATACTGGTACAATCACAGGAATATATACTGTTCTTGTAGATGGAGATGATTTTAAT
GAACCTATTGCTGATGCTGTTCGCTCTATACTTGATGGACATATTGTTCTTACACGTGACCTGGCAGATCAAGATCATTT
CCCAGCTATTGATGTATTACGCTCTATTAGCCGTTTACGATCTGATATTTGCACTCCAGAACAGGTTCAAGATGGGCGTA
TTGTGGGGAGATATATGGCAACATTTCGTAAAGCTGAAGATATGATTAATATTGGAGCATATATTCAAGGCTCTAATGAA
GAAATAGATAAAGCTATAACAATGCATGGTCCTATAGAATCATTTCTAAAACAAAATATTAGTGATCGTTCTACATTAGA
AGATTCCTTTCGTTTATTACATGATCTTGCTCATAGGTAG

Protein sequence :
MGLTPKECQKLLKESNPLRVYGKVNKVVGLVAEGTGLKSPLGAVCHMLSGNDEHGEAIAAEVVGFREGNLLFMPYGEMRG
IQPGSLIRNTSLPPVFPVGKEILGHAFNAFGEPLSGGNPIIPEKLIPLYSNPPSPLERPRIKDPLDVGVRAINSMITLGK
GQRVGIMAGSGVGKSTLMGMMARYTSADVNVIGLIGERGREVVEFMEKELGPEGMTRSVLIIATSDQSPLVRMRAAYAAT
AVAEYFRDQGKDVLLMMDSVTRFAMAAREIGLAVGEPPTTKGYTPTVFAQLPKLLERTGRSNTGTITGIYTVLVDGDDFN
EPIADAVRSILDGHIVLTRDLADQDHFPAIDVLRSISRLRSDICTPEQVQDGRIVGRYMATFRKAEDMINIGAYIQGSNE
EIDKAITMHGPIESFLKQNISDRSTLEDSFRLLHDLAHR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-84 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-84 48
escN AAC31513.1 L0034 Virulence LEE Protein 1e-76 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-77 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-76 48
escN AAC38383.1 EscN Virulence LEE Protein 8e-77 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-76 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-76 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-76 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-77 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-85 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-86 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-86 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-86 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-86 47
escN AAK26715.1 EscN Virulence LEE Protein 7e-77 47
escN AAL57542.1 EscN Virulence LEE Protein 7e-77 47
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-75 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-91 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-85 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-85 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-72 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-77 45
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-77 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-72 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 8e-73 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-72 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-72 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-76 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-76 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-70 44
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-74 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 8e-78 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-73 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-73 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-70 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-76 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-79 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 6e-77 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-77 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-72 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-67 41
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2144 Protein 4e-90 50
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2331 Protein 5e-90 49
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0048 Protein 6e-89 48
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0812 Protein 6e-77 48
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0730 Protein 4e-77 48
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2499 Protein 3e-91 48
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0390 Protein 1e-87 46
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1254 Protein 4e-93 46
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0515 Protein 5e-73 45
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0192 Protein 3e-88 44
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1778 Protein 2e-64 42
fliI YP_007365962.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1008 Protein 2e-61 41