Gene Information

Name : clpB (LAW_00125)
Accession : YP_007365210.1
Strain : Lawsonia intracellularis N343
Genome accession: NC_020127
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 155538 - 158171 bp
Length : 2634 bp
Strand : +
Note : -

DNA sequence :
ATGGATGTGAATAAGCTCACACAAAAGTCTCAAGAAGCATTATCAGAAGCACAAAGACTTTCTGCTCAATATGGGCATCA
GGAAGTAGATGTAGAACATTTAGCATTGGCACTTACCATACAAGAGAATGGTTTTGTTCCAAGGGTTCTTGAACAAGCAA
AAGTACATGTAAAAGTTGTGATTTCAGCATTAGAAGAAGTATTAAAAAAGCGTCCTTCTGTTCGTGGGCCTGGAAGTGAG
ATGGGGAAAATTACTATCTCTCAAAGGCTAAGTAAAGTTATTGCCAATGCTGAATTATTAGCAAAACGATTGGGTGATGA
GTATGTAAGTGTTGAGCATCTTTTTGCTGAATGTCTTAATGAGCCAGAGTCAACAGGAATGGGACAAGTTGCAAAAGAGA
TACACCTTACGTCACAAAGATTTATAGAAGTTATGTTAGCTGTGCGTGGGCCACACCGTGTTACATCTCCTACTCCAGAA
GATAGTTACGAAGCATTAAAAAAATATGGAAGAGATCTTGTAGAAGCTGCTCGAAAAGGAAAGCTTGATCCTGTAATTGG
ACGGGATGCTGAAATCCGTAGAGTTATCCGAATTCTTTCTCGTAGAACAAAAAATAATCCTGTGCTTATTGGTGAAGCTG
GAGTTGGGAAAACAGCTATAGTAGAAGGATTAGCTTTTCGTATCGTTCAAGGAGATGTTCCTGAAGGTTTAAAAGATAAA
TCTATTTTTGCTCTTGATATGGGGTCACTGATTGCTGGAGCAAAGTACAGAGGAGAATTTGAAGAACGTCTTAAGGCTGT
TTTAACAGAAGTCGAGAAGTCAGAAGGAAGAATTGTTCTTTTTATTGATGAATTACATACTATTGTTGGAGCAGGAAAAG
CTGATGGAGCTATGGATGCAGGGAACTTTTTAAAACCTATGCTTGCTCGTGGAGAGCTCCATTGTATTGGTGCTACAACA
TTGGATGAGTATAGAAAGTATATAGAAAAAGATCCTGCATTAGAGAGACGTTTTCAACCAGTGATGGTAGATGAACCTTC
TGTTCAAGACACTATATCTATTTTACGAGGATTAAAAGAACGCTTTGAAGTTCATCATGGTGTGAGGATTAGTGATTCTG
CTATAGTTGAAGCTGTAGTCCTTTCAGATAGATATATCTCAGATCGTCAACTACCAGACAAAGCAATTGATTTGATTGAT
GAAGCTGCAGCTATGATCCGTACAGAAATCGACTCTCTTCCATCTGAGCTTGATGAAGTTAATCGTAAAATTATGCAGTT
AGAAATAGAAAGAGAAGCCCTTAGAAAAGAAAGTGATTCAGCATCTCATGAAAGATTAGTACGTTTGGAAGAAGAATTAA
AAGTACTGCAATCAACACAGTCTGAATTAAAAAAGCAATGGGAAACTGAAAAAGGTTCAATTGATTCTCTTCGAAACATA
AAAGAACAAATTGAGCAGACACGACTTGCAATTGATGAGGCTACACGAAATGGTGAGCTAAGCAAGGCAGCAGAATTAAA
ATACTCAAAACTGTTTGAATTAGAAAAACAATTAGAAGAACGTGAATCAAAGGCTGATGGTCCACGTTTACTTAAAGAAG
AAGTTCGTCCAGATGATGTTGCTAATATTGTTGCTCGATGGACAGGTATACCTGTAACACGACTGTTAGAATCTGAAAAA
GAAAAATTGTTACGATTGCCAGATACATTACATGAGCGTGTAATTGGTCAAGATGAGGCTGTGAATGTCATATGTAATGC
TGTATTGCGTACACGTGCAGGACTTTCTGATCCAAAGAGACCACAAGGTTCTTTTATTTTTCTTGGACCTACAGGTGTTG
GTAAAACAGAACTTTGTAAAGCTCTTGCAGAATCTTTATTTGATACTGAAGAAAATATGGTTCGCTTTGATATGAGTGAA
TACATGGAGAAACACTCAGTAGCCAGGCTTATTGGAGCTCATCCTGGTTATGTAGGTTATGAAGAAGGTGGGCAACTTAC
CAATGCTGTAAAACGTAAACCTTATAGTGTCATATTATTTGACGAAGTAGAAAAAGCACATCCTGATGTATTTAATATTT
TTCTACAGTTACTTGATGATGGACGTTTGACGGATAATGCTGGCCGTACTATTAATTTTAGAAATACTATTATCATTATG
ACTTCAAATATAGGCGCATATAAATTACTTGAAGGTATTAGTCCTGATGGTTCTTTTCATGAAGGTGTATATGAGTCTGT
TATGGGTGATTTGAAACAACATTTTAGACCAGAATTTCTTAACCGAGTTGATGATGTTGTACTTTTTAAACCACTTCTGG
CTGATCAAATAAGTAGTATTATAGACTTACAGTTAAGGAGTTTAAAAAAACGCCTAGAGTCACAGAAAGTTACATTAGAA
TTAACACATTCAGCACATTTATATCTAGCTGAGAATGGATATGATCCTCATTATGGAGCACGTCCATTAAAAAGATACCT
TCAACGAGTAGTGGAAACACCTTTAGCAAAGATGATTATTAGTGGTAAAGTTCATGAAAATCAACAGATTGTTATAGATT
ACTCAGAAAGTGATTCTTCTTTACAATATGGTGTGAAAAGTGCATCTGAAGATATCAACTGGGTTCAAGTATAA

Protein sequence :
MDVNKLTQKSQEALSEAQRLSAQYGHQEVDVEHLALALTIQENGFVPRVLEQAKVHVKVVISALEEVLKKRPSVRGPGSE
MGKITISQRLSKVIANAELLAKRLGDEYVSVEHLFAECLNEPESTGMGQVAKEIHLTSQRFIEVMLAVRGPHRVTSPTPE
DSYEALKKYGRDLVEAARKGKLDPVIGRDAEIRRVIRILSRRTKNNPVLIGEAGVGKTAIVEGLAFRIVQGDVPEGLKDK
SIFALDMGSLIAGAKYRGEFEERLKAVLTEVEKSEGRIVLFIDELHTIVGAGKADGAMDAGNFLKPMLARGELHCIGATT
LDEYRKYIEKDPALERRFQPVMVDEPSVQDTISILRGLKERFEVHHGVRISDSAIVEAVVLSDRYISDRQLPDKAIDLID
EAAAMIRTEIDSLPSELDEVNRKIMQLEIEREALRKESDSASHERLVRLEEELKVLQSTQSELKKQWETEKGSIDSLRNI
KEQIEQTRLAIDEATRNGELSKAAELKYSKLFELEKQLEERESKADGPRLLKEEVRPDDVANIVARWTGIPVTRLLESEK
EKLLRLPDTLHERVIGQDEAVNVICNAVLRTRAGLSDPKRPQGSFIFLGPTGVGKTELCKALAESLFDTEENMVRFDMSE
YMEKHSVARLIGAHPGYVGYEEGGQLTNAVKRKPYSVILFDEVEKAHPDVFNIFLQLLDDGRLTDNAGRTINFRNTIIIM
TSNIGAYKLLEGISPDGSFHEGVYESVMGDLKQHFRPEFLNRVDDVVLFKPLLADQISSIIDLQLRSLKKRLESQKVTLE
LTHSAHLYLAENGYDPHYGARPLKRYLQRVVETPLAKMIISGKVHENQQIVIDYSESDSSLQYGVKSASEDINWVQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-99 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-95 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-95 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_007365210.1 ATP-dependent chaperone ClpB VFG2076 Protein 6e-118 42