Gene Information

Name : MT7199_0467 (MT7199_0467)
Accession : YP_007350205.1
Strain : Mycobacterium tuberculosis 7199-99
Genome accession: NC_020089
Putative virulence/resistance : Virulence
Product : putative ALDEHYDE DEHYDROGENASE
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 553932 - 555455 bp
Length : 1524 bp
Strand : +
Note : -

DNA sequence :
ATGACTGTCTTTTCCCGTCCCGGTTCCGCCGGGGCGCTGATGTCCTATGAATCCCGGTACCAAAACTTCATCGGGGGCCA
GTGGGTCGCGCCGGTCCATGGGCGCTACTTCGAGAACCCGACGCCGGTGACCGGCCAGCCGTTCTGCGAGGTGCCGCGCT
CCGACGCGGCCGACATCGACAAGGCGCTCGACGCCGCGCACGCGGCGGCGCCGGGGTGGGGCAAGACCGCACCGGCCGAA
CGGGCGGCGATCCTCAACATGATTGCCGACCGCATCGACAAGAACGCCGCCGCGCTGGCGGTGGCCGAGGTCTGGGACAA
CGGGAAACCGGTCCGGGAAGCGCTGGCCGCCGATATCCCGTTGGCGGTCGATCACTTCCGGTACTTCGCCGCGGCGATTC
GCGCCCAGGAGGGCGCGCTGAGCCAGATCGACGAGGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTGGGC
CAGATCATTCCGTGGAACTTCCCCATCCTGATGGCGGCCTGGAAGCTGGCGCCGGCGTTGGCGGCCGGCAACACGGCGGT
GCTCAAACCCGCCGAGCAGACACCCGCTTCGGTGCTCTACCTGATGTCGCTGATCGGTGATCTGTTGCCGCCCGGGGTGG
TCAACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGTTGGCCTCCAGCGACCGCATCGCCAAGGTCGCGTTCACC
GGGGAAACCACCACGGGGCGGCTGATCATGCAATACGCCTCGCACAACCTGATCCCGGTCACCCTGGAACTCGGCGGCAA
GAGCCCCAACATCTTCTTCGCCGACGTGCTGGCCGCCCACGACGACTTCTGCGACAAGGCGCTGGAAGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCAGTCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG
CTGGCGGCGATCCGGACCAAGGCGGTCCGGCAGGGCGACCCGCTGGACACCGAAACCATGCTGGGTTCCCAGGCCTCCAA
CGACCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGCAAGAGGGTGCGGTGATTATCGCCGGAGGCGAGCGCG
CCGAACTAGGCGGCGACCTGTCCGGCGGTTATTACATGCAGCCGACGATCTTCACCGGCACCAACAACATGCGGATTTTC
AAGGAGGAGATCTTCGGGCCGGTGGTCGCGGTGACGTCGTTCACCGATTACGACGACGCGATCGGCATCGCCAACGACAC
CCTCTACGGCTTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACACTGCCTATCGGGCCGGGCGGGACATCCAGGCCGGCC
GGGTGTGGGTCAACTGCTACCACCTCTACCCCGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAG
GGCCACCAGATGATGCTGCAGCACTACCAGCACACCAAGAACCTGCTGGTGTCCTACTCGGATAAGGCGCTGGGGTTCTT
CTGA

Protein sequence :
MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAE
RAAILNMIADRIDKNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAAAIRAQEGALSQIDEDTVAYHFHEPLGVVG
QIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT
GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE
LAAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIF
KEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGRE
GHQMMLQHYQHTKNLLVSYSDKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-128 60
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 59
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-135 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-134 59
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MT7199_0467 YP_007350205.1 putative ALDEHYDE DEHYDROGENASE VFG0082 Protein 2e-128 60