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Name : MT7199_1876 (MT7199_1876) Accession : YP_007351613.1 Strain : Mycobacterium tuberculosis 7199-99 Genome accession: NC_020089 Putative virulence/resistance : Virulence Product : Urease alpha subunit ureC (Urea amidohydrolase) Function : - COG functional category : - COG ID : - EC number : 3.5.1.5 Position : 2101728 - 2103461 bp Length : 1734 bp Strand : + Note : - DNA sequence : ATGGCGCGACTGTCAAGGGAGCGCTACGCACAGCTGTACGGACCTACCACCGGCGACCGGATACGGCTGGCCGACACCAA CCTGCTGGTTGAGGTCACCGAAGACCGGTGTGGGGGACCGGGACTGGCCGGTGACGAGGCGGTGTTCGGCGGCGGCAAGG TGCTGCGCGAGTCCATGGGCCAGGGCCGTGCGAGCCGGGCCGACGGTGCCCCCGACACCGTGATCACCGGTGCGGTGATC ATCGACTACTGGGGAATCATCAAGGCCGACATCGGGATTCGCGATGGCCGCATCGTCGGGATCGGAAAGGCCGGCAATCC CGACATCATGACAGGTGTGCATCGGGATCTCGTCGTCGGGCCGTCCACCGAAATCATCAGCGGCAACCGTCGAATCGTCA CCGCAGGCACCGTCGACTGTCACGTGCACTTGATCTGTCCGCAGATCATCGTCGAAGCCTTGGCCGCGGGCACCACCACG ATCATCGGCGGTGGCACCGGACCCGCCGAGGGCACCAAGGCCACCACAGTCACTCCCGGCGAGTGGCACCTGGCCCGGAT GCTGGAGTCACTGGACGGTTGGCCGGTGAACTTCGCGCTGCTCGGCAAGGGAAACACCGTGAATCCCGACGCACTGTGGG AACAGTTGCGCGGTGGCGCATCGGGTTTCAAACTCCACGAAGACTGGGGATCGACCCCGGCGGCCATCGACACCTGCTTG GCGGTCGCCGACGTGGCCGGGGTGCAGGTTGCGCTGCACTCCGACACTCTCAATGAGACCGGATTCGTCGAGGACACCAT CGGCGCGATCGCCGGACGTTCGATTCACGCCTACCACACCGAGGGCGCCGGCGGCGGGCACGCACCGGACATCATTACCG TCGCGGCGCAACCGAATGTACTGCCCAGCTCGACCAATCCGACCCGCCCGCATACGGTGAACACCCTTGACGAGCATCTC GACATGCTGATGGTGTGCCACCACCTCAACCCCCGGATCCCGGAGGACCTCGCGTTTGCCGAAAGCCGGATCCGACCGTC CACCATTGCGGCAGAAGATGTGTTGCACGATATGGGGGCAATCTCGATGATTGGCAGCGATTCCCAGGCGATGGGCCGTG TCGGCGAGGTGGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAAGCCCGCCGCGGGGCACTGGAAGGTGACCCGTCT GGTAGCCAAGCCGCCGACAACAACCGGGTCCGCCGCTACATCGCCAAATACACCATCTGCCCGGCCATCGCACACGGCAT GGATCACCTGATCGGTTCGGTGGAGGTGGGAAAGTTGGCCGACCTGGTGTTGTGGGAGCCGGCGTTTTTCGGGGTTCGCC CGCACGTCGTGCTCAAAGGTGGGGCGATCGCCTGGGCAGCGATGGGCGATGCGAACGCGTCAATCCCGACCCCGCAACCG GTGCTCCCGCGACCGATGTTCGGCGCGGCCGCGGCAACCGCGGCGGCGACCTCGGTGCACTTCGTCGCGCCGCAATCCAT CGACGCGCGCCTGGCGGACCGGCTCGCGGTCAATCGGGGACTAGCGCCGGTGGCCGACGTGCGCGCAGTGGGCAAGACCG ACCTGCCGCTCAATGATGCCCTACCGAGCATCGAGGTCGATCCCGACACCTTCACCGTGCGAATCGACGGCCAGGTGTGG CAACCGCAGCCGGCCGCCGAACTACCTATGACACAACGGTATTTCCTGTTCTAA Protein sequence : MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVI IDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTT IIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCL AVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHL DMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPS GSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQP VLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVW QPQPAAELPMTQRYFLF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ureC | NP_286680.1 | urease subunit alpha | Virulence | TAI | Protein | 9e-147 | 62 |
| ureC | NP_287088.1 | urease subunit alpha | Not tested | TAI | Protein | 9e-147 | 62 |
| ureC | YP_005684266.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 6e-147 | 58 |
| ureC | YP_005682174.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 6e-147 | 58 |
| ureC | YP_003784325.1 | urease subunit alpha | Not tested | PiCp 7 | Protein | 6e-147 | 58 |
| ureC | YP_005686358.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 6e-147 | 58 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| MT7199_1876 | YP_007351613.1 | Urease alpha subunit ureC (Urea amidohydrolase) | VFG0270 | Protein | 7e-131 | 55 |
