Gene Information

Name : D781_3206 (D781_3206)
Accession : YP_007345615.1
Strain : Serratia marcescens FGI94
Genome accession: NC_020064
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3371445 - 3373076 bp
Length : 1632 bp
Strand : -
Note : PFAM: AMP-binding enzyme; Domain of unknown function (DUF4009); TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGAGTATTGCATTTACCCCGTGGCCGGCCGAGTTTGCCCAGCGTTACCGCGAACGCGGCTACTGGATTGATAAACCGCT
GACCGATATTCTCGACCGCCAGGCGGACAGCGACGCGACCGCGCTGATCGATGCCGAGAATCGCCTGAGCTACCGCCAGC
TGCATCAGCAGTCGGATCGTCTGGCCGCCGCGCTGCTGCGCCGCGGCATTCAGCCGGGAGAAACCGCCCTGGTGCAGTTG
GGCAATGTGGTGGAGTTTTATGTCACCTTCTTCGCCCTGTTGAAAATTGGCGTGGCGCCGGTTAATGCGCTGTTCAGCCA
TCAGCGCAGCGAGCTGCACGCCTACGCCGAGCAAATCAAACCGGCGGTGCTGATTGCCGACGCTCAGCATGCGCTGTTCG
GCAATGACGATTTTCTGGCGACCTTCCGGGCGCAGCATCCGTCGCTGCGCGTGGTGGCGCTGCGCAGCCACGCGCAGGGC
GAGCAGTCGCTGGCGGCGATGCTGGCGGAAGAGAGCGGCGATTTCCGCGCGACGCCGTCCGCGGCCGATCGGGTGGCGTT
CTTCCAGCTGTCTGGCGGCAGCACCGGCACGCCGAAACTGATCCCGCGTACCCACAATGATTACTACTACAGCATTCGCC
GCAGCGTCGAGGTGTGCCGTTTTGACCGCGAGACGCGCTATCTGTGCGCGCTGCCGGTGGCGCACAACTACCCGATGAGC
TCGCCGGGCGTGCTGGGCGTGTTTTATGCCGCCGGTCAGGTGGTGTTTGCCGCCGATCCGGACGCCGGCCAGTGCTTCAG
ACTGATTGAACAGCATCACATCAACGTCACCGCGCTGGTGCCGCCGGCGGTCACGCTGTGGCTGCAGGCGATTGAAGAGT
GGGGCAGCAACGCGCCGCTCGCCAGCCTGCAGCTGCTGCAGGTCGGCGGCGCCAAGCTGGGTGAAAGCCTGGCGGCGCGC
ATTCCGGCGGAAATCGGCTGTCAGCTGCAGCAGGTGTTCGGCATGGCGGAAGGGTTGGTGAACTATACCCAGTTGGACGA
TGACGATCGCCATATCCTCACCACGCAGGGCTGCCCGATGTCGCCGGACGACGAAGTCTGGGTGGCCGATGACGACGGCA
ATCCGTTGCCGGCCGGCCAGGTCGGCCGTCTGATGACCCGCGGCCCGTACACCTTCCGTGGTTACTACCAGAGCCCGGCG
CACAATGCCGACGCGTTCGACGCCGACGGTTTCTACTGCTCCGGCGATCTGATCCGCATGACTGAAGACGGCTATATCTG
CGTGGAAGGGCGGCAAAAAGATCAGATCAACCGCGGCGGCGAGAAGATCGCGGCGGAAGAGATCGAAAACCTGCTGCTGC
GTCACGGCGCGGTGATTAACGCCGCGCTGGTTTCCATGCCGGATGCGCTGATGGGTGAAAAGAGCTGCGCCTATTTTATC
GCCGGCGAGACGTTAAAGCCGGTGGTGCTGCGTCGTCATCTGCGTGAGCAGGGCGTCGCCGAATTTAAATTGCCGGACCG
CTTTGTGCAGGTGGAGAGCCTGCCGCTGACGGCGGTCGGTAAAGTTGATAAGAAACTGCTGCGCCAGCGCCTGCTGGAGG
CGCAGCAAGCCACCCAGGTCCAGGGAGATTGA

Protein sequence : 
MSIAFTPWPAEFAQRYRERGYWIDKPLTDILDRQADSDATALIDAENRLSYRQLHQQSDRLAAALLRRGIQPGETALVQL
GNVVEFYVTFFALLKIGVAPVNALFSHQRSELHAYAEQIKPAVLIADAQHALFGNDDFLATFRAQHPSLRVVALRSHAQG
EQSLAAMLAEESGDFRATPSAADRVAFFQLSGGSTGTPKLIPRTHNDYYYSIRRSVEVCRFDRETRYLCALPVAHNYPMS
SPGVLGVFYAAGQVVFAADPDAGQCFRLIEQHHINVTALVPPAVTLWLQAIEEWGSNAPLASLQLLQVGGAKLGESLAAR
IPAEIGCQLQQVFGMAEGLVNYTQLDDDDRHILTTQGCPMSPDDEVWVADDDGNPLPAGQVGRLMTRGPYTFRGYYQSPA
HNADAFDADGFYCSGDLIRMTEDGYICVEGRQKDQINRGGEKIAAEEIENLLLRHGAVINAALVSMPDALMGEKSCAYFI
AGETLKPVVLRRHLREQGVAEFKLPDRFVQVESLPLTAVGKVDKKLLRQRLLEAQQATQVQGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 2e-88 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-88 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-88 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-88 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-88 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-88 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-88 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-88 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-88 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
D781_3206 YP_007345615.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 0.0 73
D781_3206 YP_007345615.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-108 46
D781_3206 YP_007345615.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-88 42