Gene Information

Name : D782_3646 (D782_3646)
Accession : YP_007341750.1
Strain : Enterobacteriaceae bacterium FGI 57
Genome accession: NC_020063
Putative virulence/resistance : Unknown
Product : type VI secretion protein IcmF
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3787730 - 3791251 bp
Length : 3522 bp
Strand : +
Note : PFAM: Protein of unknown function (DUF1215); ImcF-related N-terminal domain; Intracellular multiplication and human macrophage-killing; TIGRFAM: type VI secretion protein IcmF

DNA sequence :
GTGTTCAGATTAACGACACCCCGTATTTTTTCCAGTCTGAGGACCATGCTCAGACCGGCGATGCCCCGGTTTAAGGTTTC
TGCCTTCTGGCTGCTGATACTGGCATGGATTTTTCTGCTGGTATGGATCTGGTGGAAAGGCCCGACCTGGACATTGTACG
GAGAGCACTGGCTCAAGCCACTGACAAACCGCTGGCTGGCGACGGCAGCGTGGGGGATTATCGCTCTGGTATGGCTTACC
GTCCGGGTGATAAAGCGTCTGCAACAGCTTGAAAAACAGCAAAAGCAACAGCGTGAGGAAGCCGTTGATCCACTCAGCGT
GGAGCTGAATGCCCAGCAGCGTTACCTTGATCGCTGGCTGCTGCGTCTGCAACACCATCTCGACAACCGCCGTTATCTGT
GGCAGCTCCCCTGGTATATGGTTATCGGTCCGGCTGGCAGCGGTAAAACGGCGCTGCTGCGCGAGGGTTTTCCGTCTGAC
ATTATTTATTCCCCTGAGGTGGTCCGTGGCGCGGAGCAGCGCCTGTATCTCATCCCGCACGTCGGGCAACAGGCGGTCAT
ATTTGATATTGATGGCACACTTTGCGAACAGCCGGATGCCGATGTACTGCACCGCCGGTTATGGGAACACGCCCTGGACT
GGCTGGCGGAGAAACGCACCCGCCAGCCACTGAACGGACTTATTCTGACACTTGATTTACCTGACCTGCTGACCACCGAC
AAACGCCGCCGCGAGCATCTGTTACAGACGCTGCGCAGCCGTTTGCAGGATATCCGCCAGCATCTTCACTGCCAGTTACC
GGTCTATGTGGTACTGACACGACTGGATCTGCTGCATGGTTTTGCCACGCTGTTTCAGTCACTGGAGAAAAAAGATCGCG
ATGCCATTCTGGGTGTCACATTTACCCGTCGCGCCCATGAAAATGAAGACTGGAGAAGTGAACTCGATACCTTCTGGCAA
ACCTGGTGCGACAGGATGAACCAGGCGCTGCCGGATCTGATGCTGGCACAGAGTCACATGCGCAGCTCCCTGTTCAGCTT
TGCCCGCCAGATGCAGGGAAGCCGGGAATACCTGATGACGCTGCTGGATGGTTTGCTTGACGGCGAAAATATGGACGTCA
TGTTGCGTGGCGTCTATCTCACCTCATCACTGCAACGTGGTCAGATGGATGATATTTTTACACAATCGGCTGCCCGGCAA
TACCGACTGGGCAACAGCCCGCTGACGGCCTGGCCGCTGGTCGATACCACGCCTTATTTCACCCGCAATTTGTTTCCCCA
GGCGTTACTGGCCGAACCGAATCTGGCCGGAGAAAGTCGTACCTGGCTGGTGAGTAGCCGTCGCCGCCTGACTGTCTTTT
CCGCAACGGGCGGCGTGGCGGCGCTGATGCTCATCACCGGCTGGCACCATTATTACAAAACTAACTATGCTTCCGGCGTC
CAGGTGCTTAAACAGGCCAAAGCGTTTATGGATATCACGCCGCCTCAGGGAATAGACGACTACGGTAACCTGCAACTGCC
GCTGCTGAACCCGGTGCGTGACGCCACTCTGGCCTACGGCGACTGGGGCGACCGCAGCCGCCTGGCGGATATGGGTCTGT
ATCAGGGGCTGCGTGTCGGGCCGTATGTGGAGCAAACCTATCTGCAACTGCTGGAGCAACGTTACCTGCCTGCCCTGTTT
AACGGGCTGGTCAAAGAGATGAACGCCGCGCCCCCGGAAAGCGAGGAAAAACTTGCTGTGCTGCGTGTGATGCGAATGCT
GGAAGATAAAAGCGGGCGGAACAATGAGGCTGTGAAGCAGTATATGGCGAAACGCTGGAGCGAACAATTCCACGGCCAGC
GCGATATCCAGGCGCAACTGATGTCCCATCTTGATTACGCCCTCGCCCATACTGACTGGCACGCAGAGCGCCAGGCTGGA
GACGGTGACGCCATCAGTCGCTGGACGCCGTATGACAAGCCCGTTGTGGCAGCACAGAAAGAACTGAGCAAGTTGCCGGT
TTACCAGCGTGTTTACCAGAGCCTGAAAACACGGGCGCTGGGTGTACTGCCCGCCGACCTCAATCTGCGCGACCAGGTGG
GACCGACCTTTGACCAGGTGTTTACGTCTGCCGATGACAGCAAACTTATCGTCCCGCAGTTTCTTACCCGCTATGGCTTA
CAGAGCTACTTTGTGAAGCAGCGCGATGAACTGGTGGAGCTGACGGCAATGGATTCCTGGGTACTGAACCTGACACAAAG
CGTGAAATACAGTGACGCTGACCGTGCAGAGATCCAGCGCCAGCTCACCGAACAGTATTTCAGTGATTATACAGCCACCT
GGCGGGCAGGAATGGATAATCTTAACGTCCGGGATTATGAGTCCATTGCACAGTTGACCGGCGCACTGGAGCAGGTTATC
AGTGGAGATCAGCCTTTGCAGCGGGCGCTGACCGCCCTGCGGGATAACACACAACCTGCGATACTATCCGACAAACTGGA
TGATAAAGCCCGAGAAGAAGCACAGGCAGAACCGGATTACCGCCTGCTGACCCGCCTCGGCCATGAGTTCGCGCCAGAAA
ACAGCACACTGGCGGTTCAGAAAGATAAAGAAAGCATGATGCAGGCAGTGTATCAGCAGTTAACAGAACTGCACCGCTAC
CTGCTGGCGATCCAGAATGCGCCTGTACCGGGAAAATCGGCGCTGAAAGCCGTCCAGTTACGCCTTGACCAGAACAGCAG
CGATCCTATCTTTGCCACCCGCCAGATGGCGAAAACCCTGCCCGCGCCACTTAACCGCTGGGTGGGAAAACTGGCCGATC
AAGCCTGGCATGTGGTGATGGTGGAAGCCGTTCACTATATGGAAGTGGACTGGCGTGACAATGTGGTGAAACCGTTCAAT
GAACAGCTTGCCGGTAACTATCCGTTTAATCCGCGTGCGACACAGGATGCCTCGCTGGATGCCTTCGAACGCTTCTTCAA
ACCAGAGGGCTTGCTGGATACTTTCTATCAGCAGAATCTGAAACTGTTTATCGAAAATGATCTGAGCCGTGATGGCGATG
ACGGGGTGATTATCCGCGAGGATATTATTCAGCAACTTGAAAACGCACAGAAAATTCGCGACATCTTCTTCAGCAAACAA
AATGGCCTGGGAACACAGTTTGCGGTGGAAACAGTCTCACTTTCCGGTAACAAACGCCGCAGCGTGCTGAACCTCGACGG
CCAGTTAGTGGACTACAGCCAGGGTCGTAATTATACCGCCCATCTGGTATGGCCGAACAATATGCGGGAAGGTAATGAAA
GCAAACTGACACTGATTGGAACCAGTGGCGGAGCACCGCGCAGCCTCAGCTTCAGCGGCCCGTGGGCGCAGTTCCGCCTG
TTCGGAGCCGGACAGCTAACCGGGGTACAGGACGGCAACTTTACCGTACGCTTTAGCGTGGACGGTGGCGCAATGGTGTA
TCGAGTACACACTGACACTGAAGACAACCCGTTCAGCGGTGGGCTGTTCAGCTTATTTAAGCTGCCAGATACATTGTACT
GA

Protein sequence :
MFRLTTPRIFSSLRTMLRPAMPRFKVSAFWLLILAWIFLLVWIWWKGPTWTLYGEHWLKPLTNRWLATAAWGIIALVWLT
VRVIKRLQQLEKQQKQQREEAVDPLSVELNAQQRYLDRWLLRLQHHLDNRRYLWQLPWYMVIGPAGSGKTALLREGFPSD
IIYSPEVVRGAEQRLYLIPHVGQQAVIFDIDGTLCEQPDADVLHRRLWEHALDWLAEKRTRQPLNGLILTLDLPDLLTTD
KRRREHLLQTLRSRLQDIRQHLHCQLPVYVVLTRLDLLHGFATLFQSLEKKDRDAILGVTFTRRAHENEDWRSELDTFWQ
TWCDRMNQALPDLMLAQSHMRSSLFSFARQMQGSREYLMTLLDGLLDGENMDVMLRGVYLTSSLQRGQMDDIFTQSAARQ
YRLGNSPLTAWPLVDTTPYFTRNLFPQALLAEPNLAGESRTWLVSSRRRLTVFSATGGVAALMLITGWHHYYKTNYASGV
QVLKQAKAFMDITPPQGIDDYGNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGLRVGPYVEQTYLQLLEQRYLPALF
NGLVKEMNAAPPESEEKLAVLRVMRMLEDKSGRNNEAVKQYMAKRWSEQFHGQRDIQAQLMSHLDYALAHTDWHAERQAG
DGDAISRWTPYDKPVVAAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDSKLIVPQFLTRYGL
QSYFVKQRDELVELTAMDSWVLNLTQSVKYSDADRAEIQRQLTEQYFSDYTATWRAGMDNLNVRDYESIAQLTGALEQVI
SGDQPLQRALTALRDNTQPAILSDKLDDKAREEAQAEPDYRLLTRLGHEFAPENSTLAVQKDKESMMQAVYQQLTELHRY
LLAIQNAPVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGKLADQAWHVVMVEAVHYMEVDWRDNVVKPFN
EQLAGNYPFNPRATQDASLDAFERFFKPEGLLDTFYQQNLKLFIENDLSRDGDDGVIIREDIIQQLENAQKIRDIFFSKQ
NGLGTQFAVETVSLSGNKRRSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGGAPRSLSFSGPWAQFRL
FGAGQLTGVQDGNFTVRFSVDGGAMVYRVHTDTEDNPFSGGLFSLFKLPDTLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec30 YP_851415.1 hypothetical protein Not tested PAI II APEC-O1 Protein 0.0 79
aec30 AAQ96724.1 Aec30 Not tested AGI-1 Protein 0.0 79
pmt1 AAN64194.1 Pmt1 Not tested macrophage toxin pathogenicity island Protein 0.0 57