Gene Information

Name : D782_3243 (D782_3243)
Accession : YP_007341364.1
Strain : Enterobacteriaceae bacterium FGI 57
Genome accession: NC_020063
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3327793 - 3329403 bp
Length : 1611 bp
Strand : -
Note : PFAM: AMP-binding enzyme; Domain of unknown function (DUF4009); TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase

DNA sequence :
ATGTCTGTGGAATTTACCCGCTGGCCAGCGGACCTGGCGGCACGATACCGTGAAAAAGGCTACTGGCAGGATCTGCCGCT
GACCGATATTTTAACCCGCCACGCGAACAGTGATGCTGTAGCGGTTATTGATGGTGAACGTGAAATCAGCTATCGCCAGC
TTAACCAGGCGGTCGATAACCTGGCGTCGGCGCTTCAGTGCCAGGGGCTGAAGCAGGGCGAAACGGCGCTGGTGCAGCTT
GGCAATATTGTCGAGTTCTATATGACGCTGTTTGCGCTGCTGCGGATTGGCGTCGCGCCGGTGAATGCGCTGTTCAGCCA
TCAGCGTACTGAGCTGAATGCCTATGCCGATCAAATCGAACCGTCGCTGCTGATTGCCGATCGCACACACGCCCTGTTCG
CCGATGACAGTTTCCTGAATACCTTTATCGAAAATCATCCGTCAGTACGCGTGGTGCTGCTGCGTGGTGGCGAAGGTGAG
CACTCACTCGATGCGGCGCTGACTCAGGCGGCGGATAATTTTACCGCCACGCCAACGCCCGCTGACGAAGTGGCCTTCTT
CCAGCTTTCCGGCGGCAGCACCGGTACGCCGAAGCTGATTCCGCGTACGCATAACGATTACTACTACAGTATTCGCCGCA
GTAATGAAATTTGTCACTTCACCCCGGAAACCCGCTTCTTATGCGCGATTCCGTCGGCGCACAACTACGTGATGAGCTCG
CCGGGCGCGCTGGGCGTGTTCCTGGCCGAAGGCACCGTGGTGCTGGCCGCCGACCCGAGCGCCACGCTCTGTTTTCCGCT
GATTGAAAAACATCAGGTGAACGTGGCGGCGCTGGTGCCGCCCGCCGTCAGTCTGTGGTTACAGGCCATCGCCGAGTGGG
GAGACAATGCGTCGCTGCGTTCGCTGAAGCTGTTGCAAGTGGGCGGGGCACGGCTTTCCGCGACGCTTGCCGCACGTATT
CCGGCAGAAATTGGCTGCCAGCTTCAGCAGGTCTTCGGCATGGCGGAAGGGCTGGTGAACTACACCCGGCTGGATGATTC
CCTGGAGCGCATTATCAATACCCAGGGCCGCCCGATGTGCCCTGACGATGAAGTGTGGGTGGCCGATGAAAACGGCGAAC
CGCTGCCGCGTGGCAAAGTGGGGCGACTGATGACGCGCGGGCCGTACACCTTCCGCGGCTACTACAAAAGCCCGCAGCAC
AACGCCAGCGCCTTTGATGCCAACGGTTTCTATGGTTCCGGCGATCTCATCTCTATTGATGAAGAGGGCTACATTACCGT
CCAGGGGCGCGAGAAAGATCAGATCAACCGTGGCGGAGAGAAGATAGCCGCTGAAGAGATAGAAAACCTGCTGCTTAAGC
ATGAGTCGGTTGTCCACGCCGCGCTGGTCAGCATGGAAGACGATCTGATGGGTGAAAAAAGCTGCGCGTATCTGGTGGTG
AAAGAACCCCTGCGCGCCGTTCAGGTTCGTCGTTTCCTGCGCGAGCAGGGCGTCGCTGATTTTAAACTGCCGGATCGCGT
CGAGTGTGTGGATGAACTGCCGCTGACCCACGTCGGTAAAGTCGATAAAAAACAACTGCGTCAGTGGCTGGCTTCCCGCG
CGCTGGGCTGA

Protein sequence :
MSVEFTRWPADLAARYREKGYWQDLPLTDILTRHANSDAVAVIDGEREISYRQLNQAVDNLASALQCQGLKQGETALVQL
GNIVEFYMTLFALLRIGVAPVNALFSHQRTELNAYADQIEPSLLIADRTHALFADDSFLNTFIENHPSVRVVLLRGGEGE
HSLDAALTQAADNFTATPTPADEVAFFQLSGGSTGTPKLIPRTHNDYYYSIRRSNEICHFTPETRFLCAIPSAHNYVMSS
PGALGVFLAEGTVVLAADPSATLCFPLIEKHQVNVAALVPPAVSLWLQAIAEWGDNASLRSLKLLQVGGARLSATLAARI
PAEIGCQLQQVFGMAEGLVNYTRLDDSLERIINTQGRPMCPDDEVWVADENGEPLPRGKVGRLMTRGPYTFRGYYKSPQH
NASAFDANGFYGSGDLISIDEEGYITVQGREKDQINRGGEKIAAEEIENLLLKHESVVHAALVSMEDDLMGEKSCAYLVV
KEPLRAVQVRRFLREQGVADFKLPDRVECVDELPLTHVGKVDKKQLRQWLASRALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-90 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-90 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 42
ybtE CAA21394.1 - Virulence HPI Protein 3e-90 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 9e-90 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 4e-90 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
D782_3243 YP_007341364.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 0.0 82
D782_3243 YP_007341364.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-110 45