Gene Information

Name : hpaE (RTCIAT899_PC03860)
Accession : YP_007337117.1
Strain :
Genome accession: NC_020062
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 826537 - 828054 bp
Length : 1518 bp
Strand : -
Note : -

DNA sequence :
ATGTCCAAACTGCAGGAAAACATCGCAAAGGCCGAAGGCTTTCTCGCCCGATTCAAGGATAACGGCGTACTGAACCACGT
CAATGGCGAGGATGTGCGTGCCGATGATGGCTCCACATTCGAGACCATATCCCCCGTTGATCTGAAGCCGCTCGCAACCG
TTGCTCACGGTAAGGCTGCCGATATCGATCGCGCCGCAAAGGCCGCAAAAGCCGCCTTTGCTGAATGGGCTGCGATGCCC
GGTGACGCGCGCAAGAAACTCCTTCACAAGATTGCCGACGCGATCGTCGCCCGCGCCGAAGAGATCGCTTTTGTCGAGTG
CATGGACACCGGACAGTCGCTGAAGTTCATGGCCAAGGCCGCCCTGCGCGGCGCGGAAAACTTCCGTTTCTTCGCCGACC
GCGCACCAGAAGCGCGTGACGGCAAGGCGATCCGCGCCGACGGCCAGGTGAACCTGACAACGCGCGTTCCGATCGGCCCG
GTCGGCATCATCACGCCCTGGAATACGCCCTTCATGCTGTCGACCTGGAAGATCGCGCCGGCGCTTGCCGCCGGTTGCAC
CATCGTCCACAAGCCGGCAGAATTCTCGCCGCTGACGGCCCGCCTGCTTGTCGAAATTGCCGAGGAAGCCGGCCTGCCGA
AGGGTGTTTGGAACCTCGTCAACGGTATGGGCGAAGATGCCGGTCGTGCGCTGACGGAACATCCCCTGATCAAGGCGATC
GGTTTTGTCGGCGAAAGCCGCACCGGCTCGATGATCATGAAGCAGGGGGCAGATACGCTGAAGCGGGTGCATTTCGAGCT
TGGCGGCAAGAACCCGGTCATCGTCTTTGCCGATGCCGATCTCGAGCGCGCCGCCGATGCCGCCGTCTTCATGATCTATT
CGCTAAACGGCGAGCGCTGCACCTCGTCCTCGCGCCTGCTGGTCGAGGAAAGCGTCTACGACAAATTCACCGCGATCGTC
GCCGAAAAGGCCAAGCGCATCAAGGTCGGCCATCCCCTCGATCCTGAAACGGTCGTCGGCCCGCTCGTCCATCCCGTGCA
TGAAAAGAAGGTGCTGGAATACATTCAGATCGGCCGTTCGGAAGGTGCCACGCTTGCCGCCGGCGGCGAGAAGGTCAACG
GCCCGGGCGGTGGCTGCTACGTCTCGCCCACACTCTTCACCGGTGCCAACAACCAGATGCGCATTGCGCAGGAAGAAATC
TTCGGTCCCGTGCTGACCGCCATTCCCTTCAAGGATGAAGCCGACGCGCTGGCACTGGCCAATGACGTGCAATACGGCCT
GACCGGCTATCTCTGGACCTCCGACGTCACTCGCGCGTTCCGTTTCACCGATCATCTCGAAGCCGGCATGATCTGGGTCA
ATTCGGAAAACGTCCGTCACCTGCCCACGCCCTTCGGCGGGGTCAAGAGCTCCGGCATCGGCCGCGACGGCGGCGACTGG
TCCTTCGATTTTTACATGGAAACCAAGAACGTCGCCTTCGCCACCAAGCCGCACGCGATCCAGAAACTCGGCGGCTGA

Protein sequence :
MSKLQENIAKAEGFLARFKDNGVLNHVNGEDVRADDGSTFETISPVDLKPLATVAHGKAADIDRAAKAAKAAFAEWAAMP
GDARKKLLHKIADAIVARAEEIAFVECMDTGQSLKFMAKAALRGAENFRFFADRAPEARDGKAIRADGQVNLTTRVPIGP
VGIITPWNTPFMLSTWKIAPALAAGCTIVHKPAEFSPLTARLLVEIAEEAGLPKGVWNLVNGMGEDAGRALTEHPLIKAI
GFVGESRTGSMIMKQGADTLKRVHFELGGKNPVIVFADADLERAADAAVFMIYSLNGERCTSSSRLLVEESVYDKFTAIV
AEKAKRIKVGHPLDPETVVGPLVHPVHEKKVLEYIQIGRSEGATLAAGGEKVNGPGGGCYVSPTLFTGANNQMRIAQEEI
FGPVLTAIPFKDEADALALANDVQYGLTGYLWTSDVTRAFRFTDHLEAGMIWVNSENVRHLPTPFGGVKSSGIGRDGGDW
SFDFYMETKNVAFATKPHAIQKLGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-82 46
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-64 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-65 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hpaE YP_007337117.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 7e-66 41