Gene Information

Name : hemC (DESAM_20261)
Accession : YP_007324658.1
Strain : Desulfovibrio hydrothermalis DSM 14728
Genome accession: NC_020055
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase (hydroxymethylbilane synthase)
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.61
Position : 573571 - 574500 bp
Length : 930 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12029044, 15802251, 2110138, 9058548; Product type e : enzyme

DNA sequence : 
ATGAGAAAAATCACTATCGCAACACGTGGCAGCAAACTTGCCCTCTGGCAGGCCAATCATATTACCGATCTTCTACGTGA
AGAATACCCCGGAATCGAAGTCCAGCTGCTCAAGATTAAAACCAAGGGCGACAAAATTCTGGATGTCCCCCTTGCAAAAG
TCGGCGGCAAAGGACTTTTCGTTAAAGAAATTGAAGAGGCCCTGCTCGACAAAAGAGCCGACCTTGCCGTGCACAGCATG
AAAGATGTTCCCACTGAACTTCCTGAGGGACTTGAAGTGGGTATCATCCCGCCCCGTGAAGCTGATACTGATACCCTTCT
TTCCGTTAAATACAACTCACTCAAAGAACTGCCAGCCGGAGCCGTAGTAGGAACCAGCAGCCTGCGCAGACAATCCCAGC
TTCTTTCGTTGCGGGACGATCTCAAAATAGAATCCCTGCGCGGCAACCTGGATACCAGAGTCCGTAAGCTCCTCGATGGA
GAATTTGATGCTATCGTCGTAGCTACAGCTGGACTCAACAGACTTAATCTTTCCGCTCCTAAAAGCGAAATACTTGCGCC
TCCCACCTTCCTTCCCGCAGTAGCGCAGGGAGCACTGGGAATCGAATACAGAATAGAAGACACTGAAATTCAGGACATCC
TTGCATTTCTACACGATGAAATCAGCGCCAGACAGGTCAAAGCCGAAAGAGGATTCCTCACCGGTCTTAACGGCGGCTGT
CAGGTTCCCATTGCAGCATGGTCCCAGCGTGAAGGTGATCAGATCAAGCTGACTGGTTTTGTTGCAGATGTTGACGGCTC
CAGCCCGATTCGTCTGGAAAAAACCGGCCCTGCAGATGATGCATGGAATCTGGGAATGAGCCTTGCTGATGATGTTCTTG
CCAAAGGCGCAAAGGAAATCCTTGACCGTGTCTACAGCACAACCAGATAA

Protein sequence : 
MRKITIATRGSKLALWQANHITDLLREEYPGIEVQLLKIKTKGDKILDVPLAKVGGKGLFVKEIEEALLDKRADLAVHSM
KDVPTELPEGLEVGIIPPREADTDTLLSVKYNSLKELPAGAVVGTSSLRRQSQLLSLRDDLKIESLRGNLDTRVRKLLDG
EFDAIVVATAGLNRLNLSAPKSEILAPPTFLPAVAQGALGIEYRIEDTEIQDILAFLHDEISARQVKAERGFLTGLNGGC
QVPIAAWSQREGDQIKLTGFVADVDGSSPIRLEKTGPADDAWNLGMSLADDVLAKGAKEILDRVYSTTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-61 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-61 52