Gene Information

Name : clpB (DESAM_21912)
Accession : YP_007326286.1
Strain : Desulfovibrio hydrothermalis DSM 14728
Genome accession: NC_020055
Putative virulence/resistance : Virulence
Product : protein disaggregation chaperone
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2311690 - 2314314 bp
Length : 2625 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14550559, 14640692; Product type f : factor

DNA sequence :
ATGGATCCGAATAAATTCACAAAAAAAACTAACGATGCAATTGCTGCGGCCCAGTCTTTAGCCGTTAAAAACGGCCAGCA
ACAAATTGAAGTGGAACACCTTCTCCTTGCCCTCGTGGAACAGGAAAACGGCATTGTTTCCAAAATTATTCAGAAAAGCG
ACATTGATCCTTCGGCATATAAATCTGCCGTACAAAAGGAAATCGGCAAGCTGCCCAGTGTCAGCGGCCCCGGCGCGCAG
CCCGGACAGGTTCTTGTTACCCAGCGTCTTAACCGTATTATTGTTGAAGCCGAAGCGGCTGCCCAGCGCATGCAGGACGA
GTTTATCAGCGTGGAGCATCTGTTCCTTGCCATCATGGATGAACACGGCTCTACTGGTGCAGGGCGCGTTAATAAGTCCT
TCAACTTGACCAAAGACAAAGTGCTGGAAGCCATGACCACAATCCGCGGCAACCAGCGGGTCACGACCGATAATCCGGAA
GCAACCTATGATGCGCTTAAAAAATACGGACGTGATCTGGTAGAGGAAGCACGCAAAGGTAAACTTGATCCGGTAATCGG
ACGTGATTCTGAAATCCGCCGCGTCATCCGCATTCTGTCCCGCAGAACCAAAAACAACCCGATCCTTATCGGCGAGGCAG
GTGTTGGTAAAACAGCCATAATTGAAGGGCTGGCCCAGCGCATTGTCAAACGTGATGTGCCCGAGGGGCTTAAAGATAAA
ACCGTATTTATGCTCGACATGGGCGCGCTCATCGCCGGCGCCAAATATCGTGGTGAATTTGAAGAACGACTCAAAGCCGT
ACTTAAAGAAGTTCAGGAATCCGATGGACAGATTATCATTTTTATTGATGAAATCCATACTATCGTAGGTGCAGGAAAAT
CCGATGGTGCAATGGATGCCGGTAACCTGCTCAAACCCATGCTGGCTCGCGGAGAGCTGCACTGCATAGGCGCGACAACA
ACTGATGAGTACCGCAAGTATATTGAAAAAGATCCGGCTCTCGAAAGAAGGTTCCAGACCATTATGGTTAAAGAACCCAC
TGCCGAAGACACAATTTCTATCCTGCGCGGACTGCGTGAAAGATTTGAAGTGCACCACGGCGTGCGAATCAGCGATGCGG
CTTTAGTTGAAGCTGCGACCCTTTCACAGCGTTACATCACTGACCGTCAGCTGCCTGATAAAGCGATTGACCTCATTGAT
GAAGCTGCGGCCATGATCAGAACCGAGATTGACTCCCAGCCTTATGAGCTGGATAAGATCAACCGTCAGATTTTGCAGAC
TGAAATTGAGCGTGAAGCACTCAGACGCGAAGAGGATCAAGCTTCGCGTGAACGACTTTCCAAACTGGAAGACTCGCTCA
CCGAGATGAAGATTAAACAGTCTGAACTTGTTGAACAATGGGAAAAAGAAAAGGCATCAATCGACACTGTCCGAAACCTC
AAAGCCCAGATAGAACAGACAAAACTTCAAATCGAAGAAGCCGAAAGAAGTCTCGATTACAACCGCGCTGCGGAACTTAA
ATATTCAACCCTGCTGGGACTCGAAAAACGACTTGAAGAAATTCAGGTCGACATTGAAGGCGGTGAAGATAAAGCCTCTT
CAAATGGAAGCCGTTTACTTAAAGAATTTGTCGGGCCTGACGACATAGCCGGAATTATTTCGCGCTGGACCGGAATTCCG
GTCACCAGACTGGTTGAAGGCGAGCGTGAAAAACTGCTCCGTTTAGAAGATATCCTGCATGGAAGGGTTATCGGACAGGA
TGAGGCTGTGCGTGCTGTATCCGAAGCAGTACTGCGCGCCCGTGCAGGCCTTAAAGATCCTTCAAGACCCATCGGTTCGT
TCATCTTCCTCGGCCCGACCGGAGTAGGTAAAACGGAACTATGCAAGGCTCTTGCAGAGGCTCTATTCGACAGCGAAGAA
AATATCGTACGTATGGATATGTCCGAATACATGGAAAAACATGCGGTAGCACGGTTGATCGGAGCGCCTCCGGGCTACAT
CGGCTACGATGAAGGCGGTCAACTGACCGAGGCCATCCGCCGCAAACCTTACTCTGTTGTGCTCTTTGATGAAATAGAAA
AAGCACACAGTGATGTCTTTAACGTGCTGCTGCAAATCCTTGATGACGGACGTATCACGGATAGTCAGGGGCGCACTATA
GATTGTAAAAATACTATCATTATCATGACCTCCAACCTCGGTTCACAACTGCTGCTGGAAGGAATTGAGCCTGATGGTGA
ATTCAAAAACGGTGTTCAGGAAAATGTAATGAACGTCCTTAGCGGACACTTCAGACCGGAATTCCTCAACCGCGTTGATG
AAACAGTGCTGTTCAAGCCGCTGCTTGAGTCTGACCTCAAATTAATTGTTGATCTCCAGCTTGAAGGACTGCGCGCACGT
CTTGGCGGACAGAAAATGTCCTTGGAAGTAACAGAGAATGCTAAAGCTTTCATAGCACATGCATCCTACGACCCAGTCTA
TGGAGCCAGACCGCTGCGCCGTTATATACAGGCGCACCTTGAAACTCCGCTCGCAAAACAGATTATCGGCGGTGACCTCA
GAGAAGATCAGACCGTGACCATTGATGTAGACGCGGACGGACTCAGCTTTAATGTTGTAAGTTAA

Protein sequence :
MDPNKFTKKTNDAIAAAQSLAVKNGQQQIEVEHLLLALVEQENGIVSKIIQKSDIDPSAYKSAVQKEIGKLPSVSGPGAQ
PGQVLVTQRLNRIIVEAEAAAQRMQDEFISVEHLFLAIMDEHGSTGAGRVNKSFNLTKDKVLEAMTTIRGNQRVTTDNPE
ATYDALKKYGRDLVEEARKGKLDPVIGRDSEIRRVIRILSRRTKNNPILIGEAGVGKTAIIEGLAQRIVKRDVPEGLKDK
TVFMLDMGALIAGAKYRGEFEERLKAVLKEVQESDGQIIIFIDEIHTIVGAGKSDGAMDAGNLLKPMLARGELHCIGATT
TDEYRKYIEKDPALERRFQTIMVKEPTAEDTISILRGLRERFEVHHGVRISDAALVEAATLSQRYITDRQLPDKAIDLID
EAAAMIRTEIDSQPYELDKINRQILQTEIEREALRREEDQASRERLSKLEDSLTEMKIKQSELVEQWEKEKASIDTVRNL
KAQIEQTKLQIEEAERSLDYNRAAELKYSTLLGLEKRLEEIQVDIEGGEDKASSNGSRLLKEFVGPDDIAGIISRWTGIP
VTRLVEGEREKLLRLEDILHGRVIGQDEAVRAVSEAVLRARAGLKDPSRPIGSFIFLGPTGVGKTELCKALAEALFDSEE
NIVRMDMSEYMEKHAVARLIGAPPGYIGYDEGGQLTEAIRRKPYSVVLFDEIEKAHSDVFNVLLQILDDGRITDSQGRTI
DCKNTIIIMTSNLGSQLLLEGIEPDGEFKNGVQENVMNVLSGHFRPEFLNRVDETVLFKPLLESDLKLIVDLQLEGLRAR
LGGQKMSLEVTENAKAFIAHASYDPVYGARPLRRYIQAHLETPLAKQIIGGDLREDQTVTIDVDADGLSFNVVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-109 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-109 42
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-104 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_007326286.1 protein disaggregation chaperone VFG2076 Protein 4e-118 42