Gene Information

Name : Glo7428_5074 (Glo7428_5074)
Accession : YP_007318044.1
Strain :
Genome accession: NC_020051
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.4
Position : 63084 - 65165 bp
Length : 2082 bp
Strand : -
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase

DNA sequence :
ATGCAGCAAGAGGACGGGCATCACAAACATCAGGATCATCCGCAACGAACAACACTTGATCGTCACGACCAACACGGGCA
CAATCAAGCCGAATCATCATCGCATAGTAAAGATAGAGCGCACAACAAGCACGCTGGACATAGCCCTGAGATGTTTAAAT
GGCGCTTTTTTATTTGCCTTTTCCTGACTTTGCCGATCCTCTACTTTTCACCTTTGTTTCAAGAATGGTTTGGCTACACT
GCCATTCAGTTTCTTGGCGTGAACTTAGTCAGTCCTATTTTGGGAACAGCGATTTATTTCTATGGAGGCTGGGTATTCCT
TCAAGGAGCCTTACGCGAATTTCAAAGCAAAATAGGGATGATGACCCTAATAGCCTTAGCAATTACAGTTGCTTATGTCT
ACAGTTTGGCAGTCTCTTTAGGGCTACGTGGAGAGCCTTTTTACTGGGAACTCGCAACCCTAGTAGATGTAATGTTGCTT
GGTCATTGGATTGAATTGGTTTCAGTGCAGGGAGCAAGCCGTGCTTTGGAACATTTAGCAGATTTAGTGCCTTCTGTTGC
ACACCGACTAGTAAATGGTCAGATTGAGGATGTATCTGTAGGTGAATTGGCACAAGGAGAGCAAATTTTGATCCGCCCTG
GGGAACAAATACCGATTGATGGTGAAGTAAAAGAAGGCGTGTCAAGTGTTAACGAAGCATTTCTCACAGGCGAATCGCGT
CCTGTTACTAAACAGGCTGGTGATGAAGTCGTAGCAGGAGCCGTAAATGGAGAAGGCGCATTGACTGTAGTAGTGACGCG
AACAGGCGAGCAAACAACACTTAGCCAGGTGATGCGTTTGGTTGAGGAGGCGCAATCTTCGCGAGGGCGGTTTCAAGCAC
TTGCAGACCAAATTGCTTACTGGTTAACCTTGATTGCAATTGCAATTGGTACCTTGACGTTAGTTATTTGGCTGATGCTA
AATCCAGATCCAACTTTTGCAATCAATCGCAGCGTAACAGTATTAGTCATCACCTGTCCTCACGCTTTGGGTCTGGCAAT
TCCTCTGGTTATGGTTAATGCAACATCAATGTCTGCTAAGAATGGTATTTTAGTACGGAATCGAGAAGCCTTCGAGCGAG
CGAGGAATATTAAAACAATTGCTTTTGATAAAACAGGCACTTTGACTGAAGGACAGTTTGGAGTACAGCGAATTTATGCT
CAAGATATCAGTGACTTAGAAGCACTTGCGATCGCCGCCGCTTTAGAATCGCTATCGGAACATCCGCTAGCACAGGCAGT
CGTGGAGGAAGCAAACAATCAGCAAGTGAAACTTCCGAAAGGAAGTGAGTTTCAATCGGTGACAGGCAAAGGAATAGAAG
GTGTTGTTAACGGTAAAAGCTATCGAGTCGGGCGTTCAGAGTGGGCAGAAGAACTGGGTTTGATGTTTCCTACTGAGTTG
CAAGCAGGATTAGAGAAAATTGAAGCGCGTGGAGAAAGCGCGATTGCACTACTAGACAATAGTCAGGTTCTTGCGATATT
TGGGCTAGCTGACAAGATCCGCGAACGCGCGCGCGAAGCTGTTCAACAGCTGCAAGTCATGGATGTTCAGGTCGTAATGA
TTACCGGAGATGCCGAAGCTGTGGCAAAAACTGTTGCAGCGGAACTGAACATCGAGCAATATTATGCGCGTGTTTTACCT
CAAGATAAAGCAGCAATCATCCAGCGGTTAAAAGCAAAAAGCCCAACGGCATTTGTTGGTGATGGAATTAATGATGCTGC
CGCTTTATTTAACGCAGATCTAGGAATTGCAATTGGTGCAGGGACAAATGTAGCAATAGAATCAGCTGACTTGGTGTTAG
TTGAAAATGACCCGCTTGATGTAACGTATACACTTCAACTTGCTAAAGCAACTTATAACAAGATGATTCAGAATTTGTTT
TGGGCTACTGGGTATAACGTAGTTGGAATTCCATTAGCGGCTGGAGTTGCTGCCCCTCTAGGTATTCTACTCTCACCGGC
ATTGGGAGCCGTGTTCATGAGCCTTTCTACTGTAATTGTGTCAATTAACGCGATGTTGTTGCGCCGAGTCCAGTTAACCT
AA

Protein sequence :
MQQEDGHHKHQDHPQRTTLDRHDQHGHNQAESSSHSKDRAHNKHAGHSPEMFKWRFFICLFLTLPILYFSPLFQEWFGYT
AIQFLGVNLVSPILGTAIYFYGGWVFLQGALREFQSKIGMMTLIALAITVAYVYSLAVSLGLRGEPFYWELATLVDVMLL
GHWIELVSVQGASRALEHLADLVPSVAHRLVNGQIEDVSVGELAQGEQILIRPGEQIPIDGEVKEGVSSVNEAFLTGESR
PVTKQAGDEVVAGAVNGEGALTVVVTRTGEQTTLSQVMRLVEEAQSSRGRFQALADQIAYWLTLIAIAIGTLTLVIWLML
NPDPTFAINRSVTVLVITCPHALGLAIPLVMVNATSMSAKNGILVRNREAFERARNIKTIAFDKTGTLTEGQFGVQRIYA
QDISDLEALAIAAALESLSEHPLAQAVVEEANNQQVKLPKGSEFQSVTGKGIEGVVNGKSYRVGRSEWAEELGLMFPTEL
QAGLEKIEARGESAIALLDNSQVLAIFGLADKIRERAREAVQQLQVMDVQVVMITGDAEAVAKTVAAELNIEQYYARVLP
QDKAAIIQRLKAKSPTAFVGDGINDAAALFNADLGIAIGAGTNVAIESADLVLVENDPLDVTYTLQLAKATYNKMIQNLF
WATGYNVVGIPLAAGVAAPLGILLSPALGAVFMSLSTVIVSINAMLLRRVQLT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 3e-89 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Glo7428_5074 YP_007318044.1 heavy metal translocating P-type ATPase BAC0629 Protein 1e-148 53
Glo7428_5074 YP_007318044.1 heavy metal translocating P-type ATPase BAC0079 Protein 2e-118 42
Glo7428_5074 YP_007318044.1 heavy metal translocating P-type ATPase BAC0183 Protein 7e-81 42